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Protein

UDP-glucose 6-dehydrogenase

Gene

ESA_01534

Organism
Cronobacter sakazakii (strain ATCC BAA-894) (Enterobacter sakazakii)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

UDP-glucose + 2 NAD+ + H2O = UDP-glucuronate + 2 NADH.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei30NADUniRule annotation1
Binding sitei35NADUniRule annotation1
Binding sitei86NADUniRule annotation1
Binding sitei121NAD; via amide nitrogenUniRule annotation1
Binding sitei158NADUniRule annotation1
Active sitei266NucleophileUniRule annotation1
Binding sitei269NADUniRule annotation1
Binding sitei334NADUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseUniRule annotation
LigandNADUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
UDP-glucose 6-dehydrogenaseUniRule annotation (EC:1.1.1.22UniRule annotation)
Gene namesi
Ordered Locus Names:ESA_01534Imported
OrganismiCronobacter sakazakii (strain ATCC BAA-894) (Enterobacter sakazakii)Imported
Taxonomic identifieri290339 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeCronobacter
Proteomesi
  • UP000000260 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi290339.ESA_01534

Structurei

3D structure databases

ProteinModelPortaliA7MMI6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini320 – 424UDPG_MGDP_dh_CInterPro annotationAdd BLAST105

Sequence similaritiesi

Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C6Y Bacteria
COG1004 LUCA
HOGENOMiHOG000153773
KOiK00012
OMAiLCTEWDE

Family and domain databases

InterProiView protein in InterPro
IPR008927 6-PGluconate_DH-like_C_sf
IPR036291 NAD(P)-bd_dom_sf
IPR017476 UDP-Glc/GDP-Man
IPR014027 UDP-Glc/GDP-Man_DH_C
IPR036220 UDP-Glc/GDP-Man_DH_C_sf
IPR014026 UDP-Glc/GDP-Man_DH_dimer
IPR001732 UDP-Glc/GDP-Man_DH_N
IPR028357 UDPglc_DH_bac
PfamiView protein in Pfam
PF00984 UDPG_MGDP_dh, 1 hit
PF03720 UDPG_MGDP_dh_C, 1 hit
PF03721 UDPG_MGDP_dh_N, 1 hit
PIRSFiPIRSF500134 UDPglc_DH_bac, 1 hit
PIRSF000124 UDPglc_GDPman_dh, 1 hit
SMARTiView protein in SMART
SM00984 UDPG_MGDP_dh_C, 1 hit
SUPFAMiSSF48179 SSF48179, 1 hit
SSF51735 SSF51735, 1 hit
SSF52413 SSF52413, 1 hit
TIGRFAMsiTIGR03026 NDP-sugDHase, 1 hit

Sequencei

Sequence statusi: Complete.

A7MMI6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKVTVFGIGY VGLVQAAVLA EVGHDVMCID VDANKVENLK KGVIPIYEPG
60 70 80 90 100
LTPLVKKNYE EGRLHFSTDA AEGVNHGVMQ FIAVGTPPDE DGSADLKYVT
110 120 130 140 150
AVARTIAQHM TSHKVVLDKS TVPVGTADKV RQVMSETLKA RGVDFPFDVV
160 170 180 190 200
SNPEFLKEGA AVADCMRPER IVVGTDNDDV VELLRELYEP FNRNHDRMIL
210 220 230 240 250
MDIRSAELTK YAANCMLATK ISFMNEISNL AERLGADVEK VRQGIGSDSR
260 270 280 290 300
IGYHFIYPGC GYGGSCFPKD VQALIRTAEH IGYVPRLLKA VEDVNNDQKM
310 320 330 340 350
KLPEFIRRHF GENLEGKTFA VWGLSFKPNT DDMREASSRV LMEELWKHGA
360 370 380 390 400
TVQAYDPEAM DETQRIYGHR ADLRLMGTKE AALQGADALI ICTEWQAFRA
410 420 430 440
PDFDFIKNSL KEPVIFDGRN LYDPARLSKR GFVYYAIGRG ASINIA
Length:446
Mass (Da):49,588
Last modified:October 2, 2007 - v1
Checksum:i0805643CD1722439
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000783 Genomic DNA Translation: ABU76788.1
RefSeqiWP_004384996.1, NC_009778.1

Genome annotation databases

EnsemblBacteriaiABU76788; ABU76788; ESA_01534
GeneIDi29459755
KEGGiesa:ESA_01534

Similar proteinsi

Entry informationi

Entry nameiA7MMI6_CROS8
AccessioniPrimary (citable) accession number: A7MMI6
Entry historyiIntegrated into UniProtKB/TrEMBL: October 2, 2007
Last sequence update: October 2, 2007
Last modified: March 28, 2018
This is version 61 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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