Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

A7MMD8

- RNB_CROS8

UniProt

A7MMD8 - RNB_CROS8

Protein

Exoribonuclease 2

Gene

rnb

Organism
Cronobacter sakazakii (strain ATCC BAA-894) (Enterobacter sakazakii)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 44 (01 Oct 2014)
      Sequence version 1 (02 Oct 2007)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction.UniRule annotation

    Catalytic activityi

    Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates.UniRule annotation

    GO - Molecular functioni

    1. exoribonuclease II activity Source: UniProtKB-HAMAP
    2. RNA binding Source: UniProtKB-KW

    GO - Biological processi

    1. mRNA catabolic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Exonuclease, Hydrolase, Nuclease

    Keywords - Ligandi

    RNA-binding

    Enzyme and pathway databases

    BioCyciCSAK290339:GJ80-1584-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Exoribonuclease 2UniRule annotation (EC:3.1.13.1UniRule annotation)
    Alternative name(s):
    Exoribonuclease IIUniRule annotation
    Short name:
    RNase IIUniRule annotation
    Short name:
    Ribonuclease IIUniRule annotation
    Gene namesi
    Name:rnbUniRule annotation
    Ordered Locus Names:ESA_01589
    OrganismiCronobacter sakazakii (strain ATCC BAA-894) (Enterobacter sakazakii)
    Taxonomic identifieri290339 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeCronobacter
    ProteomesiUP000000260: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 644644Exoribonuclease 2PRO_1000063889Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi290339.ESA_01589.

    Structurei

    3D structure databases

    ProteinModelPortaliA7MMD8.
    SMRiA7MMD8. Positions 5-644.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini561 – 64383S1 motifUniRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the RNR ribonuclease family. RNase II subfamily.UniRule annotation
    Contains 1 S1 motif domain.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG4776.
    HOGENOMiHOG000271427.
    KOiK01147.
    OMAiPTAYVAE.
    OrthoDBiEOG6Q5NRD.

    Family and domain databases

    HAMAPiMF_01036. RNase_II.
    InterProiIPR011129. Cold_shock_prot.
    IPR012340. NA-bd_OB-fold.
    IPR003029. Rbsml_prot_S1_RNA-bd_dom.
    IPR022967. RNA-binding_domain_S1.
    IPR013223. RNase_B_OB_dom.
    IPR011804. RNase_II.
    IPR022966. RNase_II/R_CS.
    IPR004476. RNase_II/RNase_R.
    [Graphical view]
    PfamiPF08206. OB_RNB. 1 hit.
    PF00575. S1. 1 hit.
    [Graphical view]
    SMARTiSM00357. CSP. 1 hit.
    SM00316. S1. 1 hit.
    [Graphical view]
    SUPFAMiSSF50249. SSF50249. 4 hits.
    TIGRFAMsiTIGR00358. 3_prime_RNase. 1 hit.
    TIGR02062. RNase_B. 1 hit.
    PROSITEiPS01175. RIBONUCLEASE_II. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A7MMD8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MFQDNPLLAQ LKQQLHSQTP RAEGVVKATE KGFGFLEVDA QKSYFIPPPQ    50
    MKKVMHGDRV IAVIHTEKEK ESAEPEELIE PFLTRFVGRV QKKDDRLSIV 100
    PDHPLLKDAI PCRAERGVSH DFQNGDWAVA EMRRHPLKGD RGFYAELTQF 150
    ITFGEDHFVP WWVTLARHNL EREAPDGVAT EMLDENLTRE DLTALDFVTI 200
    DSASTEDMDD ALYVEALDGD RLQLTVAIAD PTAWIAEGSK LDNIAKVRAF 250
    TNYLPGFNIP MLPRELSDDL CSLREGVQRP ALVCRMIIEA DGAISDDIHF 300
    FAAIIESKAK LAYDDVSDWL EEKGDWQPGS EAIAAQIRLL QQICQRRSAW 350
    RTEHALVFKD RPDYRFVLGE KGEVLDIVAE PRRIANRIVE ESMIAANICA 400
    ARVLRDKLGF GVYNVHAGFD PASTEQLATL LQSHGMHVDA NDVLTLPGFC 450
    KLRRELDAQP SGFLDSRIRR FQSFAEISTE PGPHFGLGLE AYATWTSPIR 500
    KYGDMVNHRL LKAIIKGESA TRPQDEATVQ MAERRRLNRM AERDVGDWLY 550
    ARFLKDKAGT DSRFAAEIID VSRGGMRVRL VDNGAVAFIP APFLHAVRDE 600
    LVCSQENGTV QIKGETVYKV TDVIDVTIAE VRMETRSVIA RPVA 644
    Length:644
    Mass (Da):72,443
    Last modified:October 2, 2007 - v1
    Checksum:i925299EE474D4CCB
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000783 Genomic DNA. Translation: ABU76843.1.
    RefSeqiWP_012124582.1. NC_009778.1.
    YP_001437679.1. NC_009778.1.

    Genome annotation databases

    EnsemblBacteriaiABU76843; ABU76843; ESA_01589.
    GeneIDi5549705.
    KEGGiesa:ESA_01589.
    PATRICi20395255. VBICroSak107175_1417.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000783 Genomic DNA. Translation: ABU76843.1 .
    RefSeqi WP_012124582.1. NC_009778.1.
    YP_001437679.1. NC_009778.1.

    3D structure databases

    ProteinModelPortali A7MMD8.
    SMRi A7MMD8. Positions 5-644.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 290339.ESA_01589.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABU76843 ; ABU76843 ; ESA_01589 .
    GeneIDi 5549705.
    KEGGi esa:ESA_01589.
    PATRICi 20395255. VBICroSak107175_1417.

    Phylogenomic databases

    eggNOGi COG4776.
    HOGENOMi HOG000271427.
    KOi K01147.
    OMAi PTAYVAE.
    OrthoDBi EOG6Q5NRD.

    Enzyme and pathway databases

    BioCyci CSAK290339:GJ80-1584-MONOMER.

    Family and domain databases

    HAMAPi MF_01036. RNase_II.
    InterProi IPR011129. Cold_shock_prot.
    IPR012340. NA-bd_OB-fold.
    IPR003029. Rbsml_prot_S1_RNA-bd_dom.
    IPR022967. RNA-binding_domain_S1.
    IPR013223. RNase_B_OB_dom.
    IPR011804. RNase_II.
    IPR022966. RNase_II/R_CS.
    IPR004476. RNase_II/RNase_R.
    [Graphical view ]
    Pfami PF08206. OB_RNB. 1 hit.
    PF00575. S1. 1 hit.
    [Graphical view ]
    SMARTi SM00357. CSP. 1 hit.
    SM00316. S1. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50249. SSF50249. 4 hits.
    TIGRFAMsi TIGR00358. 3_prime_RNase. 1 hit.
    TIGR02062. RNase_B. 1 hit.
    PROSITEi PS01175. RIBONUCLEASE_II. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of Cronobacter sakazakii BAA-894 and comparative genomic hybridization analysis with other Cronobacter species."
      Kucerova E., Clifton S.W., Xia X.Q., Long F., Porwollik S., Fulton L., Fronick C., Minx P., Kyung K., Warren W., Fulton R., Feng D., Wollam A., Shah N., Bhonagiri V., Nash W.E., Hallsworth-Pepin K., Wilson R.K., McClelland M., Forsythe S.J.
      PLoS ONE 5:E9556-E9556(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC BAA-894.

    Entry informationi

    Entry nameiRNB_CROS8
    AccessioniPrimary (citable) accession number: A7MMD8
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 5, 2008
    Last sequence update: October 2, 2007
    Last modified: October 1, 2014
    This is version 44 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3