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A7MMD8

- RNB_CROS8

UniProt

A7MMD8 - RNB_CROS8

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Protein

Exoribonuclease 2

Gene
rnb, ESA_01589
Organism
Cronobacter sakazakii (strain ATCC BAA-894) (Enterobacter sakazakii)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction By similarity.UniRule annotation

Catalytic activityi

Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates.UniRule annotation

GO - Molecular functioni

  1. exoribonuclease II activity Source: UniProtKB-HAMAP
  2. RNA binding Source: UniProtKB-KW

GO - Biological processi

  1. mRNA catabolic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Exonuclease, Hydrolase, Nuclease

Keywords - Ligandi

RNA-binding

Enzyme and pathway databases

BioCyciCSAK290339:GJ80-1584-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Exoribonuclease 2 (EC:3.1.13.1)
Alternative name(s):
Exoribonuclease II
Short name:
RNase II
Short name:
Ribonuclease II
Gene namesi
Name:rnb
Ordered Locus Names:ESA_01589
OrganismiCronobacter sakazakii (strain ATCC BAA-894) (Enterobacter sakazakii)
Taxonomic identifieri290339 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeCronobacter
ProteomesiUP000000260: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 644644Exoribonuclease 2UniRule annotationPRO_1000063889Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi290339.ESA_01589.

Structurei

3D structure databases

ProteinModelPortaliA7MMD8.
SMRiA7MMD8. Positions 5-644.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini561 – 64383S1 motifAdd
BLAST

Sequence similaritiesi

Contains 1 S1 motif domain.

Phylogenomic databases

eggNOGiCOG4776.
HOGENOMiHOG000271427.
KOiK01147.
OMAiPTAYVAE.
OrthoDBiEOG6Q5NRD.

Family and domain databases

HAMAPiMF_01036. RNase_II.
InterProiIPR011129. Cold_shock_prot.
IPR012340. NA-bd_OB-fold.
IPR003029. Rbsml_prot_S1_RNA-bd_dom.
IPR022967. RNA-binding_domain_S1.
IPR013223. RNase_B_OB_dom.
IPR011804. RNase_II.
IPR022966. RNase_II/R_CS.
IPR004476. RNase_II/RNase_R.
[Graphical view]
PfamiPF08206. OB_RNB. 1 hit.
PF00575. S1. 1 hit.
[Graphical view]
SMARTiSM00357. CSP. 1 hit.
SM00316. S1. 1 hit.
[Graphical view]
SUPFAMiSSF50249. SSF50249. 4 hits.
TIGRFAMsiTIGR00358. 3_prime_RNase. 1 hit.
TIGR02062. RNase_B. 1 hit.
PROSITEiPS01175. RIBONUCLEASE_II. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A7MMD8-1 [UniParc]FASTAAdd to Basket

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MFQDNPLLAQ LKQQLHSQTP RAEGVVKATE KGFGFLEVDA QKSYFIPPPQ    50
MKKVMHGDRV IAVIHTEKEK ESAEPEELIE PFLTRFVGRV QKKDDRLSIV 100
PDHPLLKDAI PCRAERGVSH DFQNGDWAVA EMRRHPLKGD RGFYAELTQF 150
ITFGEDHFVP WWVTLARHNL EREAPDGVAT EMLDENLTRE DLTALDFVTI 200
DSASTEDMDD ALYVEALDGD RLQLTVAIAD PTAWIAEGSK LDNIAKVRAF 250
TNYLPGFNIP MLPRELSDDL CSLREGVQRP ALVCRMIIEA DGAISDDIHF 300
FAAIIESKAK LAYDDVSDWL EEKGDWQPGS EAIAAQIRLL QQICQRRSAW 350
RTEHALVFKD RPDYRFVLGE KGEVLDIVAE PRRIANRIVE ESMIAANICA 400
ARVLRDKLGF GVYNVHAGFD PASTEQLATL LQSHGMHVDA NDVLTLPGFC 450
KLRRELDAQP SGFLDSRIRR FQSFAEISTE PGPHFGLGLE AYATWTSPIR 500
KYGDMVNHRL LKAIIKGESA TRPQDEATVQ MAERRRLNRM AERDVGDWLY 550
ARFLKDKAGT DSRFAAEIID VSRGGMRVRL VDNGAVAFIP APFLHAVRDE 600
LVCSQENGTV QIKGETVYKV TDVIDVTIAE VRMETRSVIA RPVA 644
Length:644
Mass (Da):72,443
Last modified:October 2, 2007 - v1
Checksum:i925299EE474D4CCB
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000783 Genomic DNA. Translation: ABU76843.1.
RefSeqiWP_012124582.1. NC_009778.1.
YP_001437679.1. NC_009778.1.

Genome annotation databases

EnsemblBacteriaiABU76843; ABU76843; ESA_01589.
GeneIDi5549705.
KEGGiesa:ESA_01589.
PATRICi20395255. VBICroSak107175_1417.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000783 Genomic DNA. Translation: ABU76843.1 .
RefSeqi WP_012124582.1. NC_009778.1.
YP_001437679.1. NC_009778.1.

3D structure databases

ProteinModelPortali A7MMD8.
SMRi A7MMD8. Positions 5-644.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 290339.ESA_01589.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABU76843 ; ABU76843 ; ESA_01589 .
GeneIDi 5549705.
KEGGi esa:ESA_01589.
PATRICi 20395255. VBICroSak107175_1417.

Phylogenomic databases

eggNOGi COG4776.
HOGENOMi HOG000271427.
KOi K01147.
OMAi PTAYVAE.
OrthoDBi EOG6Q5NRD.

Enzyme and pathway databases

BioCyci CSAK290339:GJ80-1584-MONOMER.

Family and domain databases

HAMAPi MF_01036. RNase_II.
InterProi IPR011129. Cold_shock_prot.
IPR012340. NA-bd_OB-fold.
IPR003029. Rbsml_prot_S1_RNA-bd_dom.
IPR022967. RNA-binding_domain_S1.
IPR013223. RNase_B_OB_dom.
IPR011804. RNase_II.
IPR022966. RNase_II/R_CS.
IPR004476. RNase_II/RNase_R.
[Graphical view ]
Pfami PF08206. OB_RNB. 1 hit.
PF00575. S1. 1 hit.
[Graphical view ]
SMARTi SM00357. CSP. 1 hit.
SM00316. S1. 1 hit.
[Graphical view ]
SUPFAMi SSF50249. SSF50249. 4 hits.
TIGRFAMsi TIGR00358. 3_prime_RNase. 1 hit.
TIGR02062. RNase_B. 1 hit.
PROSITEi PS01175. RIBONUCLEASE_II. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome sequence of Cronobacter sakazakii BAA-894 and comparative genomic hybridization analysis with other Cronobacter species."
    Kucerova E., Clifton S.W., Xia X.Q., Long F., Porwollik S., Fulton L., Fronick C., Minx P., Kyung K., Warren W., Fulton R., Feng D., Wollam A., Shah N., Bhonagiri V., Nash W.E., Hallsworth-Pepin K., Wilson R.K., McClelland M., Forsythe S.J.
    PLoS ONE 5:E9556-E9556(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-894.

Entry informationi

Entry nameiRNB_CROS8
AccessioniPrimary (citable) accession number: A7MMD8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: October 2, 2007
Last modified: September 3, 2014
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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