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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Cronobacter sakazakii (strain ATCC BAA-894) (Enterobacter sakazakii)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotationSAAS annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei125UniRule annotation1
Active sitei533UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyaseUniRule annotationSAAS annotation
Biological processCarbon dioxide fixationUniRule annotationSAAS annotation
LigandMagnesiumUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:ESA_03811Imported
OrganismiCronobacter sakazakii (strain ATCC BAA-894) (Enterobacter sakazakii)Imported
Taxonomic identifieri290339 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeCronobacter
Proteomesi
  • UP000000260 Componenti: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi290339.ESA_03811.

Structurei

3D structure databases

ProteinModelPortaliA7ML86.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105CCA. Bacteria.
COG2352. LUCA.
HOGENOMiHOG000238648.
KOiK01595.
OMAiPWVFGWT.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1. 1 hit.
InterProiView protein in InterPro
IPR021135. PEP_COase.
IPR022805. PEP_COase_bac/pln-type.
IPR018129. PEP_COase_Lys_AS.
IPR033129. PEPCASE_His_AS.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
PfamiView protein in Pfam
PF00311. PEPcase. 1 hit.
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiView protein in PROSITE
PS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.

Sequencei

Sequence statusi: Complete.

A7ML86-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLGKLLGDTI KDALGENILD RVETIRKLSK SSRAGNEADR QALLTTLQNL
60 70 80 90 100
SNDELLPVAR AFSQFLNLAN TAEQYHSISP KGEAASNPEI IARTLRKLKD
110 120 130 140 150
QPDINETAIR QAVESLSLEL VLTAHPTEIT RRTLIHKMVE VNNCLKQLDH
160 170 180 190 200
KDIADYERNQ IMRRLRQLIA QSWHTDEIRK NRPSPVDEAK WGFAVVENSL
210 220 230 240 250
WEGVPNYLRE LNEQLEAHLD YKLPVDFVPV RFTSWMGGDR DGNPNVTADI
260 270 280 290 300
TRHVLLLSRW KATDLFLKDI QVLISELSMV ECSDALREYV GTEGAQEPYR
310 320 330 340 350
YLLKGLRAQL LATQAWLEAR LKGQKLPKPQ GLLTQNEQLW EPLYACYESL
360 370 380 390 400
VACGLGIIAN GELLDTLRRV KAFGVPLVRI DIRQESTRHT EALGELTRYL
410 420 430 440 450
GIGDYESWSE ADKQAFLIRE LNSKRPLLPR QWEPSDNTRE VLETCKVIAE
460 470 480 490 500
APKGSIAAYV ISMAKTPSDV LAVHLLLKEA GIGFALPVAP LFETLDDLNN
510 520 530 540 550
ANDVMTQLLN IDWYRGFIQG KQMVMIGYSD SAKDAGVMAA SWAQYQAQDA
560 570 580 590 600
LIKTCEKAGI ALTLFHGRGG SIGRGGAPAH AALLSQPPGS LKGGLRVTEQ
610 620 630 640 650
GEMIRFKYGL PEVTISSLSL YTSAILEANL LPPPEPKAAW RHIMDELSDI
660 670 680 690 700
SCTMYRGYVR ENNDFVPYFR SATPEQELGK LPLGSRPAKR RPTGGVESLR
710 720 730 740 750
AIPWIFAWTQ NRLMLPAWLG AGAALQKVVE DGKQDELETM CRDWPFFSTR
760 770 780 790 800
LGMLEMVFAK ADLWLAEYYD QRLVKKELWP LGRELRQLLE ADIKVVLDIA
810 820 830 840 850
NDSHLMADLP WIAESIQLRN IYTDPLNVLQ AELLHRSRLA EEEGKPADPC
860 870
VEQALMVTIA GVAAGMRNTG
Length:870
Mass (Da):97,523
Last modified:October 2, 2007 - v1
Checksum:i7B6E636BEADF7C15
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000783 Genomic DNA. Translation: ABU78997.1.

Genome annotation databases

EnsemblBacteriaiABU78997; ABU78997; ESA_03811.
KEGGiesa:ESA_03811.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiA7ML86_CROS8
AccessioniPrimary (citable) accession number: A7ML86
Entry historyiIntegrated into UniProtKB/TrEMBL: October 2, 2007
Last sequence update: October 2, 2007
Last modified: June 7, 2017
This is version 77 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported