Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

HTH-type transcriptional activator RhaR

Gene

rhaR

Organism
Cronobacter sakazakii (strain ATCC BAA-894) (Enterobacter sakazakii)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Activates expression of the rhaSR operon in response to L-rhamnose.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi195 – 214H-T-H motifUniRule annotationAdd BLAST20
DNA bindingi244 – 267H-T-H motifUniRule annotationAdd BLAST24

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Activator

Keywords - Biological processi

Rhamnose metabolism, Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
HTH-type transcriptional activator RhaRUniRule annotation
Alternative name(s):
L-rhamnose operon transcriptional activator RhaRUniRule annotation
Gene namesi
Name:rhaRUniRule annotation
Ordered Locus Names:ESA_03845
OrganismiCronobacter sakazakii (strain ATCC BAA-894) (Enterobacter sakazakii)
Taxonomic identifieri290339 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeCronobacter
Proteomesi
  • UP000000260 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003168941 – 283HTH-type transcriptional activator RhaRAdd BLAST283

Proteomic databases

PRIDEiA7ML57.

Interactioni

Subunit structurei

Binds DNA as a dimer.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sitei246Interaction with sigma-70UniRule annotation1

Protein-protein interaction databases

STRINGi290339.ESA_03845.

Structurei

3D structure databases

ProteinModelPortaliA7ML57.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains 2 HTH araC/xylS-type DNA-binding domains.UniRule annotation

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiENOG4108BRW. Bacteria.
ENOG410XYX0. LUCA.
HOGENOMiHOG000290513.
KOiK02854.
OMAiDWAAHIP.

Family and domain databases

Gene3Di1.10.10.60. 2 hits.
2.60.120.280. 1 hit.
HAMAPiMF_01533. HTH_type_RhaR. 1 hit.
InterProiIPR003313. AraC-bd.
IPR009057. Homeodomain-like.
IPR018060. HTH_AraC.
IPR018062. HTH_AraC-typ_CS.
IPR023699. Tscrpt_act_RhaR.
IPR020449. Tscrpt_reg_HTH_AraC-type.
[Graphical view]
PfamiPF02311. AraC_binding. 1 hit.
PF12833. HTH_18. 1 hit.
[Graphical view]
PRINTSiPR00032. HTHARAC.
SMARTiSM00342. HTH_ARAC. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
SSF51215. SSF51215. 1 hit.
PROSITEiPS00041. HTH_ARAC_FAMILY_1. 1 hit.
PS01124. HTH_ARAC_FAMILY_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A7ML57-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASQLVLRKA DFFATPTQPV VVADRYPQNV FAEHTHEFCE LVLVWRGNGL
60 70 80 90 100
HVLNDRPYRI TCGDLFYIRA EDRHSYQSVN DLVLHNIIYC PERLQLNVNW
110 120 130 140 150
RDLLENPRGV NGDPRWRLSS QGMVQARQVI DQLEHESPKQ DALSHCLAES
160 170 180 190 200
LFLQLAITLR RHRYQPSGGT GPGEGETLDL LMAALGNSLD VPFDLQHFCS
210 220 230 240 250
HYQIAERPLR QLFRQQTGMT ISQYLRQLRI CQAQYLLRHS SLLISEIAAR
260 270 280
CGFEDSNYFS VVFTRETGVT PRVWRQQWGA LAG
Length:283
Mass (Da):32,577
Last modified:October 2, 2007 - v1
Checksum:i44CD346A53D9E7C3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000783 Genomic DNA. Translation: ABU79031.1.
RefSeqiWP_012126093.1. NC_009778.1.

Genome annotation databases

EnsemblBacteriaiABU79031; ABU79031; ESA_03845.
GeneIDi5548602.
KEGGiesa:ESA_03845.
PATRICi20399367. VBICroSak107175_3417.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000783 Genomic DNA. Translation: ABU79031.1.
RefSeqiWP_012126093.1. NC_009778.1.

3D structure databases

ProteinModelPortaliA7ML57.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi290339.ESA_03845.

Proteomic databases

PRIDEiA7ML57.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABU79031; ABU79031; ESA_03845.
GeneIDi5548602.
KEGGiesa:ESA_03845.
PATRICi20399367. VBICroSak107175_3417.

Phylogenomic databases

eggNOGiENOG4108BRW. Bacteria.
ENOG410XYX0. LUCA.
HOGENOMiHOG000290513.
KOiK02854.
OMAiDWAAHIP.

Family and domain databases

Gene3Di1.10.10.60. 2 hits.
2.60.120.280. 1 hit.
HAMAPiMF_01533. HTH_type_RhaR. 1 hit.
InterProiIPR003313. AraC-bd.
IPR009057. Homeodomain-like.
IPR018060. HTH_AraC.
IPR018062. HTH_AraC-typ_CS.
IPR023699. Tscrpt_act_RhaR.
IPR020449. Tscrpt_reg_HTH_AraC-type.
[Graphical view]
PfamiPF02311. AraC_binding. 1 hit.
PF12833. HTH_18. 1 hit.
[Graphical view]
PRINTSiPR00032. HTHARAC.
SMARTiSM00342. HTH_ARAC. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
SSF51215. SSF51215. 1 hit.
PROSITEiPS00041. HTH_ARAC_FAMILY_1. 1 hit.
PS01124. HTH_ARAC_FAMILY_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRHAR_CROS8
AccessioniPrimary (citable) accession number: A7ML57
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: October 2, 2007
Last modified: November 2, 2016
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.