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Protein

Sialic acid transporter NanT

Gene

nanT

Organism
Cronobacter sakazakii (strain ATCC BAA-894) (Enterobacter sakazakii)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the proton-dependent transport of sialic acid.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processSugar transport, Transport

Enzyme and pathway databases

BioCyciCSAK290339:G1G9O-3441-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Sialic acid transporter NanTUniRule annotation
Alternative name(s):
Sialic acid permeaseUniRule annotation
Sialic acid/H(+) symporterUniRule annotation
Gene namesi
Name:nanTUniRule annotation
Ordered Locus Names:ESA_03611
OrganismiCronobacter sakazakii (strain ATCC BAA-894) (Enterobacter sakazakii)
Taxonomic identifieri290339 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeCronobacter
Proteomesi
  • UP000000260 Componenti: Chromosome

Subcellular locationi

  • Cell inner membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei22 – 42HelicalUniRule annotationAdd BLAST21
Transmembranei58 – 78HelicalUniRule annotationAdd BLAST21
Transmembranei86 – 106HelicalUniRule annotationAdd BLAST21
Transmembranei116 – 136HelicalUniRule annotationAdd BLAST21
Transmembranei148 – 168HelicalUniRule annotationAdd BLAST21
Transmembranei170 – 190HelicalUniRule annotationAdd BLAST21
Transmembranei224 – 244HelicalUniRule annotationAdd BLAST21
Transmembranei247 – 267HelicalUniRule annotationAdd BLAST21
Transmembranei278 – 298HelicalUniRule annotationAdd BLAST21
Transmembranei316 – 336HelicalUniRule annotationAdd BLAST21
Transmembranei353 – 375HelicalUniRule annotationAdd BLAST23
Transmembranei406 – 426HelicalUniRule annotationAdd BLAST21
Transmembranei431 – 451HelicalUniRule annotationAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10002140531 – 496Sialic acid transporter NanTAdd BLAST496

Interactioni

Protein-protein interaction databases

STRINGi290339.ESA_03611

Family & Domainsi

Sequence similaritiesi

Belongs to the major facilitator superfamily. Sialate:H(+) symporter (SHS) (TC 2.A.1.12) family. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105JHE Bacteria
ENOG410XSSD LUCA
HOGENOMiHOG000074791
KOiK03290
OMAiTPHGWRP

Family and domain databases

CDDicd06174 MFS, 1 hit
HAMAPiMF_01238 MFS_NanT, 1 hit
InterProiView protein in InterPro
IPR011701 MFS
IPR020846 MFS_dom
IPR036259 MFS_trans_sf
IPR004742 SA_transporter
PfamiView protein in Pfam
PF07690 MFS_1, 1 hit
SUPFAMiSSF103473 SSF103473, 2 hits
TIGRFAMsiTIGR00891 2A0112, 1 hit
PROSITEiView protein in PROSITE
PS50850 MFS, 1 hit

Sequencei

Sequence statusi: Complete.

A7MJD1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTKTTQLIPW YRHLNRAQWR AFSAAWLGYL LDGFDFVLIA LVLTEIQDEF
60 70 80 90 100
GLTTIQAASL ISAAFISRWF GGLMLGAMGD RYGRRLAMIS SIVLFSVGTL
110 120 130 140 150
ACGLAPGYTT LFIARLVIGI GMAGEYGASA TYVIESWPKA LRNKASGFLI
160 170 180 190 200
SGFSVGAVVA AFVYSLVVPV WGWRALFFIG ILPIVFALWL RKNIPEAHDW
210 220 230 240 250
EARRSEKTPV RTMVDILYRG EHRVINIVLT LLASVSLWLC FTGELNSAVI
260 270 280 290 300
VAALGLVCAA IFISFMVQSS GPRWPTGVTL MVIVLFAFLY SWPIQALLPT
310 320 330 340 350
YLKTELAYEP ATVARVLFFS GFGAAVGCCV GGFLGDWLGT RRAYVYSLLA
360 370 380 390 400
SQVLIIPVFA IGGANVWVLG LLLFFQQMLG QGISGILPKL IGGYFDTDQR
410 420 430 440 450
AAGLGFTYNV GALGGALAPV LGALIAERLH LGAALCSLSF GLTFVVVLLI
460 470 480 490
GLDMPSRVQR WLRPEALRTH DATDGKPLSG AQAVSGRKRG LVKSKS
Length:496
Mass (Da):53,695
Last modified:October 2, 2007 - v1
Checksum:i23D4778468AA4F25
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000783 Genomic DNA Translation: ABU78821.1
RefSeqiWP_012125979.1, NC_009778.1

Genome annotation databases

EnsemblBacteriaiABU78821; ABU78821; ESA_03611
KEGGiesa:ESA_03611
PATRICifig|290339.8.peg.3215

Similar proteinsi

Entry informationi

Entry nameiNANT_CROS8
AccessioniPrimary (citable) accession number: A7MJD1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: October 2, 2007
Last modified: March 28, 2018
This is version 60 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health