A7MH19 (GRCA_CROS8) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Autonomous glycyl radical cofactor

Gene names

Name:	grcA
Ordered Locus Names:	ESA_00681

Organism

Cronobacter sakazakii (strain ATCC BAA-894) (Enterobacter sakazakii) [Complete proteome] [HAMAP]

Taxonomic identifier

290339 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Cronobacter › Cronobacter sakazakii

Protein attributes

Sequence length	127 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Acts as a radical domain for damaged PFL and possibly other radical proteins By similarity. HAMAP-Rule MF_00806
Sequence similarities	Contains 1 glycine radical domain.

Ontologies

Keywords
PTM	Organic radical
Technical term	Complete proteome
Gene Ontology (GO)
Molecular_function	catalytic activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 127	127	Autonomous glycyl radical cofactor HAMAP-Rule MF_00806		PRO_1000083722
Regions
	Domain	5 – 127	123	Glycine radical
Amino acid modifications
	Modified residue	102	1	Glycine radical By similarity

Sequences

	Sequence		Length	Mass (Da)
	A7MH19 [UniParc]. Last modified October 2, 2007. Version 1. Checksum: 4FA5A17B4FBA9C9A	FASTA	127	14,433
	10 20 30 40 50 60 MITGIQITKA ANDSLLNSFW LLDNEKGEAR CVCAKAGFNE DDIVPVSQLG QFEYREIPME 70 80 90 100 110 120 IKPEVRVEGG QHLNVNVLRR ETLEDAVKHP EKYPQLTIRV SGYAVRFNSL TPEQQRDVIA RTFTESL

References

[1]

"Genome sequence of Cronobacter sakazakii BAA-894 and comparative genomic hybridization analysis with other Cronobacter species." Kucerova E., Clifton S.W., Xia X.Q., Long F., Porwollik S., Fulton L., Fronick C., Minx P., Kyung K., Warren W., Fulton R., Feng D., Wollam A., Shah N., Bhonagiri V., Nash W.E., Hallsworth-Pepin K., Wilson R.K., McClelland M., Forsythe S.J. PLoS ONE 5:E9556-E9556(2010) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-894.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000783 Genomic DNA. Translation: ABU75960.1.
RefSeq	YP_001436796.1. NC_009778.1.
3D structure databases
ProteinModelPortal	A7MH19.
SMR	A7MH19. Positions 64-127.
ModBase	Search...
Protein-protein interaction databases
STRING	290339.ESA_00681.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABU75960; ABU75960; ESA_00681.
GeneID	5549233.
KEGG	esa:ESA_00681.
PATRIC	20393585. VBICroSak107175_0600.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG3445.
HOGENOM	HOG000281256.
KO	K06866.
OMA	QARCVCA.
ProtClustDB	PRK11127.
Enzyme and pathway databases
BioCyc	CSAK290339:GJ80-675-MONOMER.
Family and domain databases
HAMAP	MF_00806. GrcA.
InterPro	IPR019777. Form_AcTrfase_GR_CS. IPR001150. Gly_radical. IPR011140. Glycyl_radical_cofactor_YfiD. [Graphical view]
Pfam	PF01228. Gly_radical. 1 hit. [Graphical view]
PIRSF	PIRSF000378. Gly_radicl_yfiD. 1 hit.
PROSITE	PS00850. GLY_RADICAL_1. 1 hit. PS51149. GLY_RADICAL_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GRCA_CROS8

Accession

Primary (citable) accession number: A7MH19

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 20, 2008
Last sequence update:	October 2, 2007
Last modified:	May 1, 2013
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program