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A7MH18 (A7MH18_CROS8) Unreviewed, UniProtKB/TrEMBL

Last modified May 29, 2013. Version 40. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein names
Gene names
Ordered Locus Names:ESA_00680 EMBL ABU75959.1
OrganismCronobacter sakazakii (strain ATCC BAA-894) (Enterobacter sakazakii) [Complete proteome] [HAMAP] EMBL ABU75959.1
Taxonomic identifier290339 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeCronobacter

Protein attributes

Sequence length253 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine By similarity. RuleBase RU003780

Catalytic activity

Hydrolyzes single-stranded DNA or mismatched double-stranded DNA and polynucleotides, releasing free uracil. RuleBase RU003780 SAAS SAAS002043

Sequence similarities

Belongs to the uracil-DNA glycosylase family. RuleBase RU003780

Ontologies

Keywords
   Biological processDNA damage
DNA repair RuleBase RU003780 SAAS SAAS002043
   Molecular functionGlycosidase RuleBase RU003780 SAAS SAAS002043
Hydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processbase-excision repair

Inferred from electronic annotation. Source: InterPro

   Molecular_functionuracil DNA N-glycosylase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
A7MH18 [UniParc].

Last modified October 2, 2007. Version 1.
Checksum: DCBBB1FD5635B81F

FASTA25328,223
        10         20         30         40         50         60 
MDVPVLFFGN KALSLGNRKS QESEMTDKLT WHDVLADEKE KPYFKKILTT VAAEREAGVT 

        70         80         90        100        110        120 
IYPPQKEVFN AFRFTELGDV KVVILGQDPY HGPGQAHGLA FSVRPGVAPP PSLVNMYKEL 

       130        140        150        160        170        180 
EQSVPGFTRP SHGYLESWAR QGVMLLNTVL TVQAGKAHSH ANLGWETFTD KVISLINEHR 

       190        200        210        220        230        240 
EGVVFLLWGS HAQKKGAIID RNRHHVLQAP HPSPLSAHRG FFGCGHFVKT NQYLESRGEA 

       250 
PIDWMPVLPE NAQ 

« Hide

References

[1]"Genome sequence of Cronobacter sakazakii BAA-894 and comparative genomic hybridization analysis with other Cronobacter species."
Kucerova E., Clifton S.W., Xia X.Q., Long F., Porwollik S., Fulton L., Fronick C., Minx P., Kyung K., Warren W., Fulton R., Feng D., Wollam A., Shah N., Bhonagiri V., Nash W.E., Hallsworth-Pepin K., Wilson R.K., McClelland M., Forsythe S.J.
PLoS ONE 5:E9556-E9556(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-894 EMBL ABU75959.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000783 Genomic DNA. Translation: ABU75959.1.
RefSeqYP_001436795.1. NC_009778.1.

3D structure databases

ProteinModelPortalA7MH18.
SMRA7MH18. Positions 25-253.
ModBaseSearch...

Protein-protein interaction databases

STRING290339.ESA_00680.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABU75959; ABU75959; ESA_00680.
GeneID5551260.
KEGGesa:ESA_00680.
PATRIC20393583. VBICroSak107175_0599.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0692.
HOGENOMHOG000229528.
KOK03648.
OMAAGKEIYP.
ProtClustDBPRK05254.

Enzyme and pathway databases

BioCycCSAK290339:GJ80-674-MONOMER.

Family and domain databases

Gene3D3.40.470.10. 1 hit.
HAMAPMF_00148. UDG.
InterProIPR018085. Ura-DNA_Glyclase_AS.
IPR002043. Ura_DNA_glycsylse.
IPR005122. Uracil-DNA_glycosylase-like.
[Graphical view]
PANTHERPTHR11264. PTHR11264. 1 hit.
PfamPF03167. UDG. 1 hit.
[Graphical view]
SMARTSM00986. UDG. 1 hit.
[Graphical view]
SUPFAMSSF52141. UDNA_glycsylseSF. 1 hit.
TIGRFAMsTIGR00628. ung. 1 hit.
PROSITEPS00130. U_DNA_GLYCOSYLASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA7MH18_CROS8
AccessionPrimary (citable) accession number: A7MH18
Entry history
Integrated into UniProtKB/TrEMBL: October 2, 2007
Last sequence update: October 2, 2007
Last modified: May 29, 2013
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)