Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

A7MH18

- A7MH18_CROS8

UniProt

A7MH18 - A7MH18_CROS8

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Uracil-DNA glycosylase

Gene

ung

Organism
Cronobacter sakazakii (strain ATCC BAA-894) (Enterobacter sakazakii)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.UniRule annotation

Catalytic activityi

Hydrolyzes single-stranded DNA or mismatched double-stranded DNA and polynucleotides, releasing free uracil.UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei88 – 881Proton acceptorUniRule annotation

GO - Molecular functioni

  1. uracil DNA N-glycosylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. base-excision repair Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

GlycosidaseUniRule annotation, Hydrolase

Keywords - Biological processi

DNA damage, DNA repairUniRule annotation

Enzyme and pathway databases

BioCyciCSAK290339:GJ80-674-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uracil-DNA glycosylaseUniRule annotation (EC:3.2.2.27UniRule annotation)
Short name:
UDGUniRule annotation
Gene namesi
Name:ungUniRule annotation
Ordered Locus Names:ESA_00680Imported
OrganismiCronobacter sakazakii (strain ATCC BAA-894) (Enterobacter sakazakii)Imported
Taxonomic identifieri290339 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeCronobacter
ProteomesiUP000000260: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi290339.ESA_00680.

Structurei

3D structure databases

ProteinModelPortaliA7MH18.
SMRiA7MH18. Positions 25-253.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the uracil-DNA glycosylase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0692.
HOGENOMiHOG000229528.
KOiK03648.
OMAiWARQGVM.
OrthoDBiEOG6MSS63.

Family and domain databases

Gene3Di3.40.470.10. 1 hit.
HAMAPiMF_00148. UDG.
InterProiIPR018085. Ura-DNA_Glyclase_AS.
IPR002043. Ura_DNA_glycsylse.
IPR005122. Uracil-DNA_glycosylase-like.
[Graphical view]
PANTHERiPTHR11264. PTHR11264. 1 hit.
PfamiPF03167. UDG. 1 hit.
[Graphical view]
SMARTiSM00986. UDG. 1 hit.
[Graphical view]
SUPFAMiSSF52141. SSF52141. 1 hit.
TIGRFAMsiTIGR00628. ung. 1 hit.
PROSITEiPS00130. U_DNA_GLYCOSYLASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A7MH18-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MDVPVLFFGN KALSLGNRKS QESEMTDKLT WHDVLADEKE KPYFKKILTT
60 70 80 90 100
VAAEREAGVT IYPPQKEVFN AFRFTELGDV KVVILGQDPY HGPGQAHGLA
110 120 130 140 150
FSVRPGVAPP PSLVNMYKEL EQSVPGFTRP SHGYLESWAR QGVMLLNTVL
160 170 180 190 200
TVQAGKAHSH ANLGWETFTD KVISLINEHR EGVVFLLWGS HAQKKGAIID
210 220 230 240 250
RNRHHVLQAP HPSPLSAHRG FFGCGHFVKT NQYLESRGEA PIDWMPVLPE

NAQ
Length:253
Mass (Da):28,223
Last modified:October 2, 2007 - v1
Checksum:iDCBBB1FD5635B81F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000783 Genomic DNA. Translation: ABU75959.1.
RefSeqiYP_001436795.1. NC_009778.1.

Genome annotation databases

EnsemblBacteriaiABU75959; ABU75959; ESA_00680.
GeneIDi5551260.
KEGGiesa:ESA_00680.
PATRICi20393583. VBICroSak107175_0599.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000783 Genomic DNA. Translation: ABU75959.1 .
RefSeqi YP_001436795.1. NC_009778.1.

3D structure databases

ProteinModelPortali A7MH18.
SMRi A7MH18. Positions 25-253.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 290339.ESA_00680.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABU75959 ; ABU75959 ; ESA_00680 .
GeneIDi 5551260.
KEGGi esa:ESA_00680.
PATRICi 20393583. VBICroSak107175_0599.

Phylogenomic databases

eggNOGi COG0692.
HOGENOMi HOG000229528.
KOi K03648.
OMAi WARQGVM.
OrthoDBi EOG6MSS63.

Enzyme and pathway databases

BioCyci CSAK290339:GJ80-674-MONOMER.

Family and domain databases

Gene3Di 3.40.470.10. 1 hit.
HAMAPi MF_00148. UDG.
InterProi IPR018085. Ura-DNA_Glyclase_AS.
IPR002043. Ura_DNA_glycsylse.
IPR005122. Uracil-DNA_glycosylase-like.
[Graphical view ]
PANTHERi PTHR11264. PTHR11264. 1 hit.
Pfami PF03167. UDG. 1 hit.
[Graphical view ]
SMARTi SM00986. UDG. 1 hit.
[Graphical view ]
SUPFAMi SSF52141. SSF52141. 1 hit.
TIGRFAMsi TIGR00628. ung. 1 hit.
PROSITEi PS00130. U_DNA_GLYCOSYLASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome sequence of Cronobacter sakazakii BAA-894 and comparative genomic hybridization analysis with other Cronobacter species."
    Kucerova E., Clifton S.W., Xia X.Q., Long F., Porwollik S., Fulton L., Fronick C., Minx P., Kyung K., Warren W., Fulton R., Feng D., Wollam A., Shah N., Bhonagiri V., Nash W.E., Hallsworth-Pepin K., Wilson R.K., McClelland M., Forsythe S.J.
    PLoS ONE 5:E9556-E9556(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-894Imported.

Entry informationi

Entry nameiA7MH18_CROS8
AccessioniPrimary (citable) accession number: A7MH18
Entry historyi
Integrated into UniProtKB/TrEMBL: October 2, 2007
Last sequence update: October 2, 2007
Last modified: October 29, 2014
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3