Reviewed, UniProtKB/Swiss-Prot A7MGS0 (GLND_ENTS8)

Names and origin

Protein names

Recommended name:
    [Protein-PII] uridylyltransferase
      Short name=PII uridylyl-transferase
    EC=2.7.7.59
Alternative name(s):
    Uridylyl-removing enzyme
    UTase

Gene names

Name:	glnD
Ordered Locus Names:	ESA_03176

Organism

Enterobacter sakazakii (strain ATCC BAA-894) [Complete proteome] [HAMAP]

Taxonomic identifier

290339 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Cronobacter

Protein attributes

Sequence length	892 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Modifies, by uridylylation or deuridylylation the PII (glnB) regulatory protein By similarity.
Catalytic activity	UTP + [protein-PII] = diphosphate + uridylyl-[protein-PII]. HAMAP MF_00277
Sequence similarities	Belongs to the glnD family.

Ontologies

Keywords
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	nitrogen compound metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	[protein-PII] uridylyltransferase activity Inferred from electronic annotation. Source: HAMAP amino acid binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 892	892	[Protein-PII] uridylyltransferase HAMAP MF_00277		PRO_1000022342

Sequences

	Sequence		Length	Mass (Da)
	A7MGS0-1 [UniParc]. Last modified October 2, 2007. Version 1. Checksum: 99E2B1D75E7F6B4E	FASTA	892	103,003
	10 20 30 40 50 60 MMSNTLPEQS VNTTLAPLPG QPDYPATWPA DALNCAQIKQ HLDAFQQWLG AAFDDGYTAE 70 80 90 100 110 120 QLIEARTEFI DQLLQRLWIA AGFGDTPDTA LVAVGGYGRG ELHPLSDIDL LILSRKRLSE 130 140 150 160 170 180 AQAQKVGELL TLLWDVKLEV GHSVRTLEEC LLEGLSDLTV ATNLIESRLL IGDVALFLEL 190 200 210 220 230 240 QKHIFSDGFW PSEKFFAAKV EEQNERHQRY HGTSYNLEPD IKSSPGGLRD IHTLQWVARR 250 260 270 280 290 300 HFGATSLREM VGFGFLTEAE RNELDECQHL LWRIRFALHL ELNRYDNRLL FDRQLSVAQR 310 320 330 340 350 360 LRYEGEGNEP VEHMMKDFYR VTRRVGELNQ MLLQLFDEAI LALTTDEKPR VLDDDFQLRG 370 380 390 400 410 420 TLIDLRDETL FIREPQAILR MFYMMVRNRD ITGIYSTTLR HLRHARRHLK QPLCYIPEAR 430 440 450 460 470 480 SLFLAMLRHP GAVSRGLLPM HRHSVLWAYM PQWSHIVGQM QFDLFHAYTV DEHTIRVLLK 490 500 510 520 530 540 LESFAKEETR AKHPLCVDLW PRLSHPELIL IAALFHDIAK GRGGDHSVLG AQDILKFAEL 550 560 570 580 590 600 HGLNSRETQL VAWLVRHHLL MSVTAQRRDI QDPEVIKQFA EEVQTENRLR FLVCLTVADI 610 620 630 640 650 660 CATNETLWNS WKQSLLRELY FATEKQLRRG MQSTPDMRER VRHHQLQALA LLRMENIDEE 670 680 690 700 710 720 ALHHIWGRCR ANYFVRHSPN QLAWHARHLL RHDLSKPLIL LSPQATRGGT EIFIWSPDRP 730 740 750 760 770 780 YLFAAVCAEL DRRNLSVHDA QIFTTRDDMA MDTFIVLEPD GSPLSPDRHE AIRHGLEQAI 790 800 810 820 830 840 TQRTWQPPQP RRQPAKLRHF TVETEVNFLP THTDRKSFLE LIALDQPGLL ARVGQVFADL 850 860 870 880 890 GISLHGARIS TIGERVEDLF IIATADRRGL NNLLQQEVRQ RLTEDLNPND KV

References

[1]	McClelland M., Sanderson E.K., Porwollik S., Spieth J., Clifton W.S., Fulton B., Wollam A., Shah N., Pepin K., Bhonagiri V., Nash W., Johnson M., Thiruvilangam P., Wilson R. Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000783 Genomic DNA. Translation: ABU78398.1.
RefSeq	YP_001439234.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A7MGS0.
Genome annotation databases
GeneID	5549477.
GenomeReviews	Gene locus ESA_03176 in contig CP000783_GR.
KEGG	esa:ESA_03176.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	MQHDLFH.
Family and domain databases
HAMAP	MF_00277. [Tree]
InterPro	IPR002912. ACT_bd. IPR010043. GlnD_Uridyltrans. IPR003607. Met-dep_phosphohydro_HD. IPR006674. Met-dep_phosphohydro_HD_sub. IPR002934. Nucleotidyltransferase. IPR013546. PII_UdlTrfase/GS_AdlTrfase. [Graphical view]
PANTHER	PTHR13734:SF1. GlnD_Uridyltrans. 1 hit.
Pfam	PF01842. ACT. 2 hits. PF08335. GlnD_UR_UTase. 1 hit. PF01966. HD. 1 hit. PF01909. NTP_transf_2. 1 hit. [Graphical view]
PIRSF	PIRSF006288. PII_uridyltransf. 1 hit.
SMART	SM00471. HDc. 1 hit. [Graphical view]
TIGRFAMs	TIGR01693. UTase_glnD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GLND_ENTS8

Accession

Primary (citable) accession number: A7MGS0

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	October 2, 2007
Last modified:	November 3, 2009
This is version 14 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)