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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Cronobacter sakazakii (strain ATCC BAA-894) (Enterobacter sakazakii)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:ESA_01360
OrganismiCronobacter sakazakii (strain ATCC BAA-894) (Enterobacter sakazakii)
Taxonomic identifieri290339 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeCronobacter
Proteomesi
  • UP000000260 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000180261 – 577Arginine--tRNA ligaseAdd BLAST577

Proteomic databases

PRIDEiA7MEC0

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi290339.ESA_01360

Structurei

3D structure databases

ProteinModelPortaliA7MEC0
SMRiA7MEC0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi123 – 133"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C75 Bacteria
COG0018 LUCA
HOGENOMiHOG000247212
KOiK01887
OMAiNKPLHLG

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.70, 1 hit
3.40.50.620, 1 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

A7MEC0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNIQALLSEK VSQALIAAGA PADCEPQVRQ SAKAQFGDYQ ANGVMAIAKK
60 70 80 90 100
LGMPPRQFAE QALAHLDLTG IAAKTEIAGP GFINIFLDPA FLAKNIEAAV
110 120 130 140 150
ASDRAGVEKV SAPQTIVVDY SAPNVAKEMH VGHVRSTIIG DASVRTLEFL
160 170 180 190 200
GHKVIRANHV GDWGTQFGML IAYLEKQQQE NAGEMALSDL EGFYREAKKH
210 220 230 240 250
YDEDEAFAER ARSYVVKLQG GDEYCREMWR KLVDITMTQN QITYQRLNVT
260 270 280 290 300
LTRDDVMGES LYNPMLPGIV ADLKAKGLAV ESEGATVVFL DEFKNKEGEP
310 320 330 340 350
MGVIIQKKDG GYLYTTTDIA CAKYRYETLH ADRVLYYIDS RQHQHLMQAW
360 370 380 390 400
TIVRKAGYVP ESVPLEHHMF GMMLGKDGKP FKTRAGGTIK LSELLDEALD
410 420 430 440 450
RARRLVAGKN PDMPADELEK LANAVGIGAV KYADLSKSRT TDYIFDWDNM
460 470 480 490 500
LAFEGNTAPY MQYAYTRVLS VFRKAGVKES ELTAPVVIQD DREAQLAARL
510 520 530 540 550
LQFEETLGVV ARDGTPHVMC AYLYDLAGLF SGFYEHCPIL TAETDALRQS
560 570
RLKLALLTAK TLKLGLDTLG IETVERM
Length:577
Mass (Da):63,926
Last modified:October 2, 2007 - v1
Checksum:i33EA0CB3C397DE56
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000783 Genomic DNA Translation: ABU76620.1
RefSeqiWP_004387403.1, NC_009778.1

Genome annotation databases

EnsemblBacteriaiABU76620; ABU76620; ESA_01360
GeneIDi29459474
KEGGiesa:ESA_01360

Similar proteinsi

Entry informationi

Entry nameiSYR_CROS8
AccessioniPrimary (citable) accession number: A7MEC0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: October 2, 2007
Last modified: June 20, 2018
This is version 62 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

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