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Protein

Pyridoxal-dependent decarboxylase domain-containing protein 1

Gene

PDXDC1

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Cofactori

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDecarboxylase, Lyase
LigandPyridoxal phosphate

Names & Taxonomyi

Protein namesi
Recommended name:
Pyridoxal-dependent decarboxylase domain-containing protein 1 (EC:4.1.1.-)
Gene namesi
Name:PDXDC1
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 25

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003112151 – 787Pyridoxal-dependent decarboxylase domain-containing protein 1Add BLAST787

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei653PhosphoserineBy similarity1
Modified residuei688PhosphothreonineBy similarity1
Modified residuei692PhosphothreonineBy similarity1
Modified residuei711PhosphoserineBy similarity1
Modified residuei719PhosphoserineBy similarity1
Modified residuei723PhosphoserineBy similarity1
Modified residuei747PhosphoserineBy similarity1
Modified residuei785PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiA7MBC2.
PeptideAtlasiA7MBC2.
PRIDEiA7MBC2.

Expressioni

Gene expression databases

BgeeiENSBTAG00000004801.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000043763.

Structurei

3D structure databases

ProteinModelPortaliA7MBC2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family.Curated

Phylogenomic databases

eggNOGiKOG0630. Eukaryota.
ENOG410XYFU. LUCA.
GeneTreeiENSGT00390000009628.
HOGENOMiHOG000115485.
HOVERGENiHBG069100.
InParanoidiA7MBC2.
OMAiHLALISH.
OrthoDBiEOG091G066W.
TreeFamiTF313101.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiView protein in InterPro
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major.
PfamiView protein in Pfam
PF00282. Pyridoxal_deC. 1 hit.
SUPFAMiSSF53383. SSF53383. 2 hits.

Sequencei

Sequence statusi: Complete.

A7MBC2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDASLEKKIA DPTLAEMGKN LKEAMKMLED SQRRTEEENG KKLLSGDIPG
60 70 80 90 100
PLQGSGQDMV SILQLVQNLM HGDEDEQPQS TRIQNIGEQG HISLLGHSLG
110 120 130 140 150
AYISTLDKEK LRKLTTRILS DTTLWLCRIF RYENGCAYFH EEEREGLAKI
160 170 180 190 200
CRLAIHSRYE DFVVDGFNVL YNRKPVLYLS AAARPGLGQY LCNQLGLPFP
210 220 230 240 250
CLCRVPCNTV FGSQHQMDVA FLEKLIKDDI ERGKLPLLLV ANAGTAAVGH
260 270 280 290 300
TDKIGRLKEV CEQYGIWLHV EGVNLATLAL GYVSSSVLAA TKCDSMTLTP
310 320 330 340 350
GPWLGLPAVP AVTLYKHDDP ALTLVSGLTS NKPADKLRAL PLWLSLQYLG
360 370 380 390 400
LDGIVERIKH ACQLSQRLQE SLKKVNHIKI LVEDELSSPV VVFRFFQELP
410 420 430 440 450
GSDPGLNAIP APSAAASAVG RERHSCDALN RWLGEQLKQL VPMSGLTVMD
460 470 480 490 500
LEVEGTCVRF SPLMTAAVLG TRGEDVDQLV ACVQSKLPVL TCTLQLREEF
510 520 530 540 550
KQEVEATAGL LYVDDPNWPG IGVVRYEHAN DDKSSLKLDP EGEKIHAGLL
560 570 580 590 600
KKLNELESDL TFKMGPEYKS MKSCIYIGMA SDDIDISELV ETIAVTAREI
610 620 630 640 650
EEDSRLLENM TEVVRKGIQE AQVQLQKANE ERLLEEGVLR QIPVVGSVLN
660 670 680 690 700
WFSPVQASQK GRTFNLTAGS LESTEHTYVY KVQGSGVTPP QTPTGTRTKQ
710 720 730 740 750
RLPGQKPFKR SLRGSDAISE TSSVGHIEDL EKMEQSSGGQ EASEANSHER
760 770 780
HPEAPAPPEA EPPGALQDGA QGLQDDRPQV EEPESLR
Length:787
Mass (Da):86,615
Last modified:October 2, 2007 - v1
Checksum:i9303DF36A3167EDB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC151480 mRNA. Translation: AAI51481.1.
RefSeqiNP_001095329.1. NM_001101859.2.
UniGeneiBt.12962.

Genome annotation databases

EnsembliENSBTAT00000046463; ENSBTAP00000043763; ENSBTAG00000004801.
GeneIDi505868.
KEGGibta:505868.

Similar proteinsi

Entry informationi

Entry nameiPDXD1_BOVIN
AccessioniPrimary (citable) accession number: A7MBC2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 13, 2007
Last sequence update: October 2, 2007
Last modified: February 28, 2018
This is version 64 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome