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Protein
Submitted name:

SKP2 protein

Gene

SKP2

Organism
Bos taurus (Bovine)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Enzyme and pathway databases

ReactomeiR-BTA-174178 APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
R-BTA-187577 SCF(Skp2)-mediated degradation of p27/p21
R-BTA-5689880 Ub-specific processing proteases
R-BTA-69231 Cyclin D associated events in G1
R-BTA-8939902 Regulation of RUNX2 expression and activity
R-BTA-8951664 Neddylation
R-BTA-983168 Antigen processing: Ubiquitination & Proteasome degradation

Names & Taxonomyi

Protein namesi
Submitted name:
SKP2 proteinImported
Gene namesi
Name:SKP2Imported
OrganismiBos taurus (Bovine)Imported
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome 20

Expressioni

Gene expression databases

BgeeiENSBTAG00000013562

Interactioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000018036

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini94 – 140F-boxInterPro annotationAdd BLAST47

Phylogenomic databases

eggNOGiKOG2120 Eukaryota
ENOG410Z2W2 LUCA
GeneTreeiENSGT00390000007918
HOGENOMiHOG000247037
HOVERGENiHBG047488
KOiK03875
OMAiEIWGIRC
OrthoDBiEOG091G0EYN
TreeFamiTF352582

Family and domain databases

Gene3Di3.80.10.10, 1 hit
InterProiView protein in InterPro
IPR036047 F-box-like_dom_sf
IPR001810 F-box_dom
IPR006553 Leu-rich_rpt_Cys-con_subtyp
IPR032675 LRR_dom_sf
PfamiView protein in Pfam
PF12937 F-box-like, 1 hit
SMARTiView protein in SMART
SM00256 FBOX, 1 hit
SM00367 LRR_CC, 4 hits
SUPFAMiSSF81383 SSF81383, 1 hit
PROSITEiView protein in PROSITE
PS50181 FBOX, 1 hit

Sequencei

Sequence statusi: Complete.

A7MB09-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHRKHLQEIP DQSSNVTTSF TWGWDSSKTS ELLSGMGVSA LEKEEVDSEN
60 70 80 90 100
IPQELLSNLG HPQSPPRKRL KSKGNDKDFV IVRRPKLNRE NFPGVSWDSL
110 120 130 140 150
PDELLLGIFS CLCLPELLKV SSVCKRWYHL AFDESLWQTV DLAGRNLYPD
160 170 180 190 200
VVGRLLSRGV VAFRCPRSFM DQPLVEHFSP FRLQHLDLSN SVIDASTLHG
210 220 230 240 250
LLSHCSKLQN LSLEGLRLSD PVVDNLAQNT NLLRLNLSGC SGFSESALKT
260 270 280 290 300
LLSSCSRLDE LNLSWCYDFT EKHVQMAVAH VSKTITQLNL SGYRKNLQRS
310 320 330 340 350
DVSTLVGRCP NLVHLDLSDS VMLKNDCFPE FYQLNYLQHL SLSRCYDIIP
360 370 380 390 400
ETLLELGEIP TLKTLQVFGI VPDGTLQLLK EALPHLQINC SHFTTIARPT
410 420
IGNKKNQEIW GIKCRLSLEK PSCL
Length:424
Mass (Da):47,820
Last modified:October 2, 2007 - v1
Checksum:i593779A41CAD7FF0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DAAA02050644 Genomic DNA No translation available.
BC151275 mRNA Translation: AAI51276.1
RefSeqiNP_001095522.1, NM_001102052.1
UniGeneiBt.24638

Genome annotation databases

EnsembliENSBTAT00000018036; ENSBTAP00000018036; ENSBTAG00000013562
GeneIDi519018
KEGGibta:519018

Similar proteinsi

Entry informationi

Entry nameiA7MB09_BOVIN
AccessioniPrimary (citable) accession number: A7MB09
Entry historyiIntegrated into UniProtKB/TrEMBL: October 2, 2007
Last sequence update: October 2, 2007
Last modified: March 28, 2018
This is version 84 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health