Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Histone deacetylase

Gene

hda-6

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

Hydrolysis of an N6-acetyl-lysine residue of a histone to yield a deacetylated histone.SAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChromatin regulatorSAAS annotation, HydrolaseSAAS annotation
Biological processTranscription, Transcription regulationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Histone deacetylaseSAAS annotation (EC:3.5.1.98SAAS annotation)
Gene namesi
Name:hda-6Imported
ORF Names:CELE_F41H10.6Imported, F41H10.6Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome IV

Organism-specific databases

WormBaseiF41H10.6c; CE41132; WBGene00018319; hda-6.

Subcellular locationi

  • Nucleus SAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

NucleusSAAS annotation

PTM / Processingi

Proteomic databases

PaxDbiA7LPD8.
PeptideAtlasiA7LPD8.

Expressioni

Gene expression databases

BgeeiWBGene00018319.
ExpressionAtlasiA7LPD8. baseline.

Structurei

3D structure databases

ProteinModelPortaliA7LPD8.
SMRiA7LPD8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini875 – 936UBP-typeInterPro annotationAdd BLAST62

Phylogenomic databases

eggNOGiKOG1343. Eukaryota.
COG0123. LUCA.
GeneTreeiENSGT00530000062809.
HOGENOMiHOG000004769.
OMAiQPHGFCI.
OrthoDBiEOG091G0210.
PhylomeDBiA7LPD8.

Family and domain databases

Gene3Di3.30.40.10. 1 hit.
3.40.800.20. 2 hits.
InterProiView protein in InterPro
IPR000286. His_deacetylse.
IPR023801. His_deacetylse_dom.
IPR013083. Znf_RING/FYVE/PHD.
IPR001607. Znf_UBP.
PANTHERiPTHR10625. PTHR10625. 1 hit.
PfamiView protein in Pfam
PF00850. Hist_deacetyl. 2 hits.
PF02148. zf-UBP. 1 hit.
PRINTSiPR01270. HDASUPER.
SMARTiView protein in SMART
SM00290. ZnF_UBP. 1 hit.
PROSITEiView protein in PROSITE
PS50271. ZF_UBP. 1 hit.

Sequencei

Sequence statusi: Complete.

A7LPD8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLFEDRQKNR STGPTLIGFN QTQNEHENTV CPTHPESSDR ILKIKEALTK
60 70 80 90 100
TKILEKCTVL TNFLEIDDAD LEVTHDKSMV KDLMESEKKT QEDINSQCEK
110 120 130 140 150
YDSVFMTEFQ NSMKVAKDGV ACVRDLTNRI MANEASNGFA VVRPPGHHAD
160 170 180 190 200
SVSPCGFCLF NNVAQAAEEA FFSGAERILI VDLDVHHGHG TQRIFYDDKR
210 220 230 240 250
VLYFSIHRHE HGLFWPHLPE SDFDHIGSGK GLGYNANLAL NETGCTDSDY
260 270 280 290 300
LSIIFHVLLP LATQFDPHFV IISAGFDALL GDPLGGMCLT PDGYSHILYH
310 320 330 340 350
LKSLAQGRML VVLEGGYNHQ ISAVAVQRCV RVLLGYAPFS IELNEAPKES
360 370 380 390 400
TVDSCVSLVS VLRHHWNCFD YFPSRTSLRL AQWPIVNTKV IYNYDPTTRR
410 420 430 440 450
ADTGEIIQDE LASTEFTASD VIPTENMETL IYFNEGDDAH FDLEEDNHPE
460 470 480 490 500
KPARTRRILK TLRESGVLEK CVDRNCERIA TNEEIRLVHT KKMLEHLRTT
510 520 530 540 550
ETMKDEELME EAEKEFNSIY LTRDTLKVAR KAVGAVLQSV DEIFEKDAGQ
560 570 580 590 600
RNALVIVRPP GHHASASKSS GFCIFNNVAV AAKYAQRRHK AKRVLILDWD
610 620 630 640 650
VHHGNGTQEI FYEDSNVMYM SIHRHDKGNF YPIGEPKDYS DVGEGAGEGM
660 670 680 690 700
SVNVPFSGVQ MGDNEYQMAF QRVIMPIAYQ FNPDLVLISA GFDAAVDDPL
710 720 730 740 750
GEYKVTPETF ALMTYQLSSL AGGRIITVLE GGYNLTSISN SAQAVCEVLQ
760 770 780 790 800
NRSMLRRLRE EKEQFATKPQ KIESSCIKTI REVCAVQQKY WSILKGFQVT
810 820 830 840 850
PSNYGLDIDD EAYDDDSIDM ADQSSSSGSS SSSTRPSHNL EIMDSGPAHA
860 870 880 890 900
VVPLATCPHL KEVKPLPPAK INARTACSEC QIGAEVWTCL TCYKYNCGRF
910 920 930 940 950
VNEHAMMHHL SSSHPMALSM ADLSVWCYPC DSYVHNPALI GAKSAAHESK

FGETMPS
Length:957
Mass (Da):107,024
Last modified:September 11, 2007 - v1
Checksum:iC2D025AFB4920FD2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284604 Genomic DNA. Translation: CCD71106.1.
RefSeqiNP_001122780.1. NM_001129308.2.
UniGeneiCel.12964.

Genome annotation databases

EnsemblMetazoaiF41H10.6c; F41H10.6c; WBGene00018319.
GeneIDi177316.
UCSCiF41H10.6c. c. elegans.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiA7LPD8_CAEEL
AccessioniPrimary (citable) accession number: A7LPD8
Entry historyiIntegrated into UniProtKB/TrEMBL: September 11, 2007
Last sequence update: September 11, 2007
Last modified: July 5, 2017
This is version 81 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported