Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

ABC transporter C family MRP4

Gene

MRP4

Organism
Zea mays (Maize)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at transcript leveli

Functioni

ABC transporter that may affect phytic acid transport and compartmentalization. May function directly or indirectly in removing phytic acid from the cytosol or in vesicle trafficking. Required for phytic acid accumulation in developing seeds. Phytic acid is the primary storage form of phosphorus in cereal grains and other plant seeds.1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi664 – 671ATPPROSITE-ProRule annotation8
Nucleotide bindingi1301 – 1308ATPPROSITE-ProRule annotation8

GO - Molecular functioni

GO - Biological processi

  • transmembrane transport Source: UniProtKB

Keywordsi

Molecular functionHydrolase
Biological processTransport
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
ABC transporter C family MRP4Curated (EC:3.6.3.-Curated)
Alternative name(s):
Multidrug resistance-associated protein 4Curated
Short name:
ZmMRP41 Publication
Protein LOW PHYTIC ACID 11 Publication
Gene namesi
Name:MRP41 Publication
Synonyms:LPA11 Publication
OrganismiZea mays (Maize)
Taxonomic identifieri4577 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaePACMAD cladePanicoideaeAndropogonodaeAndropogoneaeTripsacinaeZea
Proteomesi
  • UP000007305 Componenti: Unplaced

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei12 – 32Helical; Name=1Sequence analysisAdd BLAST21
Transmembranei55 – 75Helical; Name=2Sequence analysisAdd BLAST21
Transmembranei78 – 98Helical; Name=3Sequence analysisAdd BLAST21
Transmembranei109 – 129Helical; Name=4Sequence analysisAdd BLAST21
Transmembranei138 – 158Helical; Name=5Sequence analysisAdd BLAST21
Transmembranei177 – 197Helical; Name=6Sequence analysisAdd BLAST21
Transmembranei319 – 339Helical; Name=7Sequence analysisAdd BLAST21
Transmembranei342 – 362Helical; Name=8Sequence analysisAdd BLAST21
Transmembranei373 – 393Helical; Name=9Sequence analysisAdd BLAST21
Transmembranei427 – 447Helical; Name=10Sequence analysisAdd BLAST21
Transmembranei453 – 473Helical; Name=11Sequence analysisAdd BLAST21
Transmembranei540 – 560Helical; Name=12Sequence analysisAdd BLAST21
Transmembranei945 – 965Helical; Name=13Sequence analysisAdd BLAST21
Transmembranei985 – 1005Helical; Name=14Sequence analysisAdd BLAST21
Transmembranei1060 – 1082Helical; Name=15Sequence analysisAdd BLAST23
Transmembranei1086 – 1108Helical; Name=16Sequence analysisAdd BLAST23
Transmembranei1154 – 1174Helical; Name=17Sequence analysisAdd BLAST21
Transmembranei1179 – 1199Helical; Name=18Sequence analysisAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Disruption phenotypei

Strong reduction in seed phytic acid, and strong increase of inorganic phosphate and myo-inositol levels in seeds.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004318851 – 1510ABC transporter C family MRP4Add BLAST1510

Proteomic databases

PaxDbiA7KVC2.

Expressioni

Tissue specificityi

Expressed in roots, leaves, stalks, tassels, silks, developing seeds and developing embryos.1 Publication

Interactioni

Protein-protein interaction databases

STRINGi4577.GRMZM5G820122_P01.

Structurei

3D structure databases

ProteinModelPortaliA7KVC2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini320 – 595ABC transmembrane type-1 1PROSITE-ProRule annotationAdd BLAST276
Domaini629 – 852ABC transporter 1PROSITE-ProRule annotationAdd BLAST224
Domaini950 – 1220ABC transmembrane type-1 2PROSITE-ProRule annotationAdd BLAST271
Domaini1267 – 1501ABC transporter 2PROSITE-ProRule annotationAdd BLAST235

Sequence similaritiesi

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0054. Eukaryota.
COG1132. LUCA.

Family and domain databases

InterProiView protein in InterPro
IPR003593. AAA+_ATPase.
IPR011527. ABC1_TM_dom.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR027417. P-loop_NTPase.
PfamiView protein in Pfam
PF00664. ABC_membrane. 2 hits.
PF00005. ABC_tran. 2 hits.
SMARTiView protein in SMART
SM00382. AAA. 2 hits.
SUPFAMiSSF52540. SSF52540. 2 hits.
SSF90123. SSF90123. 2 hits.
PROSITEiView protein in PROSITE
PS50929. ABC_TM1F. 2 hits.
PS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 2 hits.

Sequencei

Sequence statusi: Complete.

A7KVC2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPPSFPSLPL PEAVAATAHA ALLALAALLL LLRAARALAS RCASCLKAPR
60 70 80 90 100
RRGGPAVVVG DGAGGALAAA TAGAWHRAVL ASCAYALLSQ VAVLSYEVAV
110 120 130 140 150
AGSRVSARAL LLPAVQAVSW AALLALALQA RAVGWARFPA LVRLWWVVSF
160 170 180 190 200
ALCVVIAYDD SRRLIGQGAR AVDYAHMVAN FASVPALGFL CLVGVMGSTG
210 220 230 240 250
LELEFTEDGN GLHEPLLLGR QRREAEEELG CLRVTPYADA GILSLATLSW
260 270 280 290 300
LSPLLSVGAQ RPLELADIPL LAHKDRAKSC YKAMSAHYER QRLEYPGREP
310 320 330 340 350
SLTWAILKSF WREAAVNGTF AAVNTIVSYV GPYLISYFVD YLSGNIAFPH
360 370 380 390 400
EGYILASIFF VAKLLETLTA RQWYLGVDIM GIHVKSGLTA MVYRKGLRLS
410 420 430 440 450
NASRQSHTSG EIVNYMAVDV QRVGDYAWYF HDIWMLPLQI ILALAILYKN
460 470 480 490 500
VGIAMVSTLV ATVLSIAASV PVAKLQEHYQ DKLMASKDER MRKTSECLKN
510 520 530 540 550
MRILKLQAWE DRYRLQLEEM RNVECRWLRW ALYSQAAVTF VFWSSPIFVA
560 570 580 590 600
VITFGTCILL GGQLTAGGVL SALATFRILQ EPLRNFPDLI SMMAQTRVSL
610 620 630 640 650
DRLSHFLQQE ELPDDATINV PQSSTDKAVD IKDGAFSWNP YTLTPTLSDI
660 670 680 690 700
HLSVVRGMRV AVCGVIGSGK SSLLSSILGE IPKLCGHVRI SGTAAYVPQT
710 720 730 740 750
AWIQSGNIEE NILFGSQMDR QRYKRVIAAC CLKKDLELLQ YGDQTVIGDR
760 770 780 790 800
GINLSGGQKQ RVQLARALYQ DADIYLLDDP FSAVDAHTGS ELFKEYILTA
810 820 830 840 850
LATKTVIYVT HQVEFLPAAD LILVLKDGHI TQAGKYDDLL QAGTDFNALV
860 870 880 890 900
SAHKEAIETM DIFEDSDSDT VSSIPNKRLT PSISNIDNLK NKMCENGQPS
910 920 930 940 950
NTRGIKEKKK KEERKKKRTV QEEERERGKV SSKVYLSYMG EAYKGTLIPL
960 970 980 990 1000
IILAQTMFQV LQIASNWWMA WANPQTEGDA PKTDSVVLLV VYMSLAFGSS
1010 1020 1030 1040 1050
LFVFMRSLLV ATFGLAAAQK LFIKMLRCVF RAPMSFFDTT PSGRILNRVS
1060 1070 1080 1090 1100
VDQSVVDLDI AFRLGGFAST TIQLLGIVAV MSKVTWQVLI LIVPMAVACM
1110 1120 1130 1140 1150
WMQRYYIASS RELTRILSVQ KSPVIHLFSE SIAGAATIRG FGQEKRFMKR
1160 1170 1180 1190 1200
NLYLLDCFAR PLFSSLAAIE WLCLRMELLS TFVFAFCMAI LVSFPPGTIE
1210 1220 1230 1240 1250
PSMAGLAVTY GLNLNARMSR WILSFCKLEN RIISVERIYQ YCRLPSEAPL
1260 1270 1280 1290 1300
IIENCRPPSS WPQNGNIELI DLKVRYKDDL PLVLHGVSCM FPGGKKIGIV
1310 1320 1330 1340 1350
GRTGSGKSTL IQALFRLIEP TGGKIIIDNI DISAIGLHDL RSRLSIIPQD
1360 1370 1380 1390 1400
PTLFEGTIRM NLDPLEECTD QEIWEALEKC QLGEVIRSKE EKLDSPVLEN
1410 1420 1430 1440 1450
GDNWSVGQRQ LIALGRALLK QAKILVLDEA TASVDTATDN LIQKIIRSEF
1460 1470 1480 1490 1500
KDCTVCTIAH RIPTVIDSDL VLVLSDGKIA EFDTPQRLLE DKSSMFIQLV
1510
SEYSTRSSCI
Length:1,510
Mass (Da):166,790
Last modified:September 11, 2007 - v1
Checksum:i1CDA695DE219CA53
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EF586878 mRNA. Translation: ABS81429.1.
RefSeqiNP_001106060.1. NM_001112590.1.
UniGeneiZm.21953.

Genome annotation databases

GeneIDi100125659.
KEGGizma:100125659.

Similar proteinsi

Entry informationi

Entry nameiAB4C_MAIZE
AccessioniPrimary (citable) accession number: A7KVC2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 4, 2015
Last sequence update: September 11, 2007
Last modified: April 12, 2017
This is version 61 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families