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Protein

Phosphate acetyltransferase

Gene

H058_08060

Organism
Vibrio antiquarius (strain Ex25)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Involved in acetate metabolism.UniRule annotation

Catalytic activityi

Acetyl-CoA + phosphate = CoA + acetyl phosphate.UniRule annotation

Pathwayi: acetyl-CoA biosynthesis

This protein is involved in step 2 of the subpathway that synthesizes acetyl-CoA from acetate.UniRule annotation
Proteins known to be involved in the 2 steps of the subpathway in this organism are:
  1. Acetate kinase (ackA), Acetate kinase (ackA), Acetate kinase (ackA)
  2. Phosphate acetyltransferase (H058_08060)
This subpathway is part of the pathway acetyl-CoA biosynthesis, which is itself part of Metabolic intermediate biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes acetyl-CoA from acetate, the pathway acetyl-CoA biosynthesis and in Metabolic intermediate biosynthesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAcyltransferaseUniRule annotationSAAS annotationImported, Transferase

Enzyme and pathway databases

BioCyciVSP150340:GJJG-1460-MONOMER.
UniPathwayiUPA00340; UER00459.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphate acetyltransferaseUniRule annotation (EC:2.3.1.8UniRule annotation)
Alternative name(s):
PhosphotransacetylaseUniRule annotation
Gene namesi
ORF Names:H058_08060Imported, VEx25_B0012Imported
OrganismiVibrio antiquarius (strain Ex25)Imported
Taxonomic identifieri150340 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio
Proteomesi
  • UP000184767 Componenti: Unassembled WGS sequence

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini233 – 344DRTGGInterPro annotationAdd BLAST112
Domaini391 – 706PTA_PTBInterPro annotationAdd BLAST316

Domaini

The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.UniRule annotation

Sequence similaritiesi

In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.UniRule annotation
In the N-terminal section; belongs to the CobB/CobQ family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000053797.
OMAiVTPLMFE.

Family and domain databases

Gene3Di3.40.1390.20. 1 hit.
InterProiView protein in InterPro
IPR010766. DRTGG.
IPR016475. P-Actrans_bac.
IPR027417. P-loop_NTPase.
IPR004614. P_AcTrfase.
IPR002505. PTA_PTB.
IPR028979. Ser_kin/Pase_Hpr-like_N_sf.
PfamiView protein in Pfam
PF07085. DRTGG. 1 hit.
PF01515. PTA_PTB. 1 hit.
PIRSFiPIRSF006107. PhpActrans_proteobac. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
SSF75138. SSF75138. 1 hit.
TIGRFAMsiTIGR00651. pta. 1 hit.

Sequencei

Sequence statusi: Complete.

A7K4K1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSRTIMLIPT SAGVGLTSVS MGVLRAMERK GVKVSFYKPI CQPRSGGDQP
60 70 80 90 100
DLTSTIVGHN SDMKIGEPMA MSVAESLIGN DNMDELLETV VERYNQINKD
110 120 130 140 150
ADVTLIEGLV PTRKHPFANQ VNAEIAATLG AEIVLVATPG TDNPAQLKER
160 170 180 190 200
IEVACSNFGG TKNKNISGVI INKLNAPVDE AGRTRPDLSE IFDDADSAKQ
210 220 230 240 250
NELKVMEIFN TSPIRVLGCV PWSIDLIATR AIDMAKHLKA DIINEGDINT
260 270 280 290 300
RRIKSITFCA RSLPNMIEHF KPGSLLVTSA DRPDVIVAAS LAAMNGVDIG
310 320 330 340 350
AVLLTGGYDI PREIEGLCKP AFDTGLPIFK AQGNTWQTSL NLQSFSIEVP
360 370 380 390 400
ADDKERIEFI NEHVAGHIDG NWIESMTEGT QKSRRLSPPA FRYQLTELAR
410 420 430 440 450
KAGKRIVLPE GDEPRTVKAA AICAERGIAD CVLLGNPDEI RRVAAQQGVE
460 470 480 490 500
LGTGVTIIDA DAVRENYVAR LVELRGAKGM TEVVAREKLQ DSVFLGTMML
510 520 530 540 550
ENDEVDGLVS GAVHTTANTI VPPFQIIKTA PNASIVSSVF FMLLPDQVLV
560 570 580 590 600
YGDCAINPDP TAEQLAEIAI QSADSAAAFG IDPRVAMISY STGESGKGAD
610 620 630 640 650
VDKVREATRI AKEKRPDLVI DGPLQYDAAI MENVAASKAP NSPVAGKATV
660 670 680 690 700
FVFPDLNTGN TTYKAVQRSA DLVSIGPMLQ GMRKPVNDLS RGALVDDIVY
710
TIALTAIQAD QEAK
Length:714
Mass (Da):76,698
Last modified:September 11, 2007 - v1
Checksum:i0922E8741F6E9EF0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS267835 Genomic DNA. Translation: EDN56472.1.
AOJB01000043 Genomic DNA. Translation: OKQ14214.1.
RefSeqiWP_005396636.1. NZ_DS267835.1.

Genome annotation databases

EnsemblBacteriaiACY51129; ACY51129; VEA_002967.
EDN56472; EDN56472; VEx25_B0012.

Similar proteinsi

Entry informationi

Entry nameiA7K4K1_VIBAE
AccessioniPrimary (citable) accession number: A7K4K1
Entry historyiIntegrated into UniProtKB/TrEMBL: September 11, 2007
Last sequence update: September 11, 2007
Last modified: November 22, 2017
This is version 67 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported