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A7JQU5

- A7JQU5_PASHA

UniProt

A7JQU5 - A7JQU5_PASHA

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Protein
Submitted name:

Glutathione transferase

Gene

MHA_0454

Organism
Mannheimia haemolytica PHL213
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei10 – 101GlutathioneImported
Binding sitei36 – 361GlutathioneImported
Binding sitei40 – 401GlutathioneImported
Binding sitei53 – 531Glutathione; via amide nitrogen and carbonyl oxygenImported

GO - Molecular functioni

  1. glutathione transferase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

TransferaseImported

Names & Taxonomyi

Protein namesi
Submitted name:
Glutathione transferaseImported (EC:2.5.1.18Imported)
Gene namesi
ORF Names:MHA_0454Imported
OrganismiMannheimia haemolytica PHL213Imported
Taxonomic identifieri272629 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeMannheimia

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4IQ1X-ray1.85A/B/C1-209[»]
4IW9X-ray1.76A/B/C1-209[»]
ProteinModelPortaliA7JQU5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni65 – 662Glutathione bindingImported
Regioni102 – 1043Glutathione bindingImported

Sequence similaritiesi

Belongs to the GST superfamily.UniRule annotation

Family and domain databases

Gene3Di1.20.1050.10. 1 hit.
3.40.30.10. 1 hit.
InterProiIPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR004046. GST_C.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamiPF00043. GST_C. 1 hit.
PF13417. GST_N_3. 1 hit.
[Graphical view]
SUPFAMiSSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
PROSITEiPS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A7JQU5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKLYGLTGAC SFVPHVALEW VKLRANQDYA FQAVSREFIK SAEYLALNPR
60 70 80 90 100
GNVPLLVDGD LALTQNQAIV HYLDELYPEA KLFGSKTARD KAKAARWLAF
110 120 130 140 150
FNSDVHKSFV PLFRLPSYAE GNETLTKTIR QQSAEQILEQ LAFANAHLEN
160 170 180 190 200
HIFFGEEISV ADAYLYIMLN WCRLLGLDFS HLSQLSAFMQ RVEADQGVDN

VREQEGLKG
Length:209
Mass (Da):23,645
Last modified:September 11, 2007 - v1
Checksum:iA5FC09FBA2115ACA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS264611 Genomic DNA. Translation: EDN73431.1.

Genome annotation databases

EnsemblBacteriaiEDN73431; EDN73431; MHA_0454.
PATRICi28796897. VBIManHae426_0408.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS264611 Genomic DNA. Translation: EDN73431.1 .

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
4IQ1 X-ray 1.85 A/B/C 1-209 [» ]
4IW9 X-ray 1.76 A/B/C 1-209 [» ]
ProteinModelPortali A7JQU5.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai EDN73431 ; EDN73431 ; MHA_0454 .
PATRICi 28796897. VBIManHae426_0408.

Family and domain databases

Gene3Di 1.20.1050.10. 1 hit.
3.40.30.10. 1 hit.
InterProi IPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR004046. GST_C.
IPR012336. Thioredoxin-like_fold.
[Graphical view ]
Pfami PF00043. GST_C. 1 hit.
PF13417. GST_N_3. 1 hit.
[Graphical view ]
SUPFAMi SSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
PROSITEi PS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The genome sequence of Mannheimia haemolytica A1: insights into virulence, natural competence, and Pasteurellaceae phylogeny."
    Gioia J., Qin X., Jiang H., Clinkenbeard K., Lo R., Liu Y., Fox G.E., Yerrapragada S., McLeod M.P., McNeill T.Z., Hemphill L., Sodergren E., Wang Q., Muzny D.M., Homsi F.J., Weinstock G.M., Highlander S.K.
    J. Bacteriol. 188:7257-7266(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: PHL213Imported.
  2. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: PHL213Imported.
  3. "Crystal structure of probable glutathione s-transferase MHA_0454 (TARGET EFI-507015) FROM Mannheimia haemolytica, Substrate-free."
    Enzyme Function Initiative (EFI)
    Patskovsky Y., Toro R., Bhosle R., Hillerich B., Seidel R.D., Washington E., Scott Glenn A., Chowdhury S., Evans B., Hammonds J., Zencheck W.D., Imker H.J., AL Obaidi N.F., Stead M., Love J., Gerlt J.A., Armstrong R.N., Almo S.C.
    Submitted (JAN-2013) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (1.85 ANGSTROMS).
  4. "Crystal Structure of Probable Glutathione S-Transferase Mha_0454 (Target Efi-507015) from Mannheimia Haemolytica."
    Enzyme Function Initiative (EFI)
    Patskovsky Y., Toro R., Bhosle R., Hillerich B., Seidel R.D., Washington E., Scott Glenn A., Chowdhury S., Evans B., Hammonds J., Zencheck W.D., Imker H.J., Al Obaidi N., Stead M., Love J., Gerlt J.A., Armstrong R.N., Almo S.C.
    Submitted (JAN-2013) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (1.76 ANGSTROMS) IN COMPLEX WITH GLUTATHIONE.

Entry informationi

Entry nameiA7JQU5_PASHA
AccessioniPrimary (citable) accession number: A7JQU5
Entry historyi
Integrated into UniProtKB/TrEMBL: September 11, 2007
Last sequence update: September 11, 2007
Last modified: November 26, 2014
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureImported

External Data

Dasty 3