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Protein
Submitted name:

Cadherin FAT1 isoform +12

Gene

Fat1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

  1. actin filament organization Source: MGI
  2. establishment or maintenance of cell polarity Source: MGI
  3. single organismal cell-cell adhesion Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Cadherin FAT1 isoform +12Imported
Gene namesi
Name:Fat1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:109168. Fat1.

Subcellular locationi

GO - Cellular componenti

  1. cell-cell junction Source: MGI
  2. cell junction Source: MGI
  3. extracellular vesicular exosome Source: MGI
  4. filopodium Source: MGI
  5. focal adhesion Source: MGI
  6. lamellipodium Source: MGI
  7. nucleus Source: MGI
  8. perinuclear region of cytoplasm Source: MGI
  9. plasma membrane Source: MGI
Complete GO annotation...

PTM / Processingi

Proteomic databases

PaxDbiA7ISQ0.

Expressioni

Gene expression databases

ExpressionAtlasiA7ISQ0. baseline and differential.
GenevestigatoriA7ISQ0.

Family & Domainsi

Phylogenomic databases

eggNOGiNOG12793.
HOGENOMiHOG000046499.

Sequencei

Sequence statusi: Fragment.

A7ISQ0-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
SWDFDYDAKV VDLDPCLSKK PLEEKPSQPY SARESLSEVQ SLSSFQSESC
60 70 80
DDNESLAAPD LSKPRGYHWD TSDWMPSVPL PD
Length:82
Mass (Da):9,252
Last modified:September 11, 2007 - v1
Checksum:iDB61351E52A38899
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei82 – 821Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ320124 mRNA. Translation: ABC59054.1.
UniGeneiMm.27365.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ320124 mRNA. Translation: ABC59054.1.
UniGeneiMm.27365.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PaxDbiA7ISQ0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

MGIiMGI:109168. Fat1.

Phylogenomic databases

eggNOGiNOG12793.
HOGENOMiHOG000046499.

Miscellaneous databases

NextBioi35545066.
SOURCEiSearch...

Gene expression databases

ExpressionAtlasiA7ISQ0. baseline and differential.
GenevestigatoriA7ISQ0.

Family and domain databases

ProtoNetiSearch...

Publicationsi

  1. "Differentially spliced isoforms of FAT1 are asymmetrically distributed within migrating cells."
    Braun G.S., Kretzler M., Heider T., Floege J., Holzman L.B., Kriz W., Moeller M.J.
    J. Biol. Chem. 282:22823-22833(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6Imported.

Entry informationi

Entry nameiA7ISQ0_MOUSE
AccessioniPrimary (citable) accession number: A7ISQ0
Entry historyi
Integrated into UniProtKB/TrEMBL: September 11, 2007
Last sequence update: September 11, 2007
Last modified: February 4, 2015
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.