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Protein
Submitted name:

C-X-C motif chemokine receptor 6

Gene

Cxcr6

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionG-protein coupled receptorUniRule annotationSAAS annotation, Receptor, Transducer

Enzyme and pathway databases

ReactomeiR-RNO-380108 Chemokine receptors bind chemokines
R-RNO-418594 G alpha (i) signalling events

Names & Taxonomyi

Protein namesi
Submitted name:
C-X-C motif chemokine receptor 6Imported
Submitted name:
Chemokine receptor CXCR6Imported
Gene namesi
Name:Cxcr6Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 8

Organism-specific databases

RGDi1642118 Cxcr6

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei41 – 66HelicalSequence analysisAdd BLAST26
Transmembranei78 – 98HelicalSequence analysisAdd BLAST21
Transmembranei118 – 143HelicalSequence analysisAdd BLAST26
Transmembranei155 – 178HelicalSequence analysisAdd BLAST24
Transmembranei198 – 220HelicalSequence analysisAdd BLAST23
Transmembranei241 – 265HelicalSequence analysisAdd BLAST25
Transmembranei277 – 302HelicalSequence analysisAdd BLAST26

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSRNOG00000006319

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000008294

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini57 – 297G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST241

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG3656 Eukaryota
ENOG410XRW9 LUCA
GeneTreeiENSGT00760000118785
HOGENOMiHOG000234122
HOVERGENiHBG106917
KOiK04191
OMAiTPFNLVK
OrthoDBiEOG091G0D3V
TreeFamiTF330966

Family and domain databases

InterProiView protein in InterPro
IPR002235 Chemokine_CXCR6
IPR000355 Chemokine_rcpt
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM
PANTHERiPTHR10489:SF705 PTHR10489:SF705, 1 hit
PfamiView protein in Pfam
PF00001 7tm_1, 1 hit
PRINTSiPR00657 CCCHEMOKINER
PR01105 CXCCHMKINER6
PR00237 GPCRRHODOPSN
PROSITEiView protein in PROSITE
PS00237 G_PROTEIN_RECEP_F1_1, 1 hit
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit

Sequencei

Sequence statusi: Complete.

A7ISD5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDDGHQEKDL DDDVYGGDPW LFNNSSGNSQ EHKRFLKFKE VFLPCMYLVV
60 70 80 90 100
FVLGLLGNSL VLIIYIFYQR LRSLTDVFLL NLPLADLVFV CTLPFWAYAG
110 120 130 140 150
TYEWVFGTAM CKTLRSMYAM NFYVSMLTLT CITVDRFVVV VQATKAFNRQ
160 170 180 190 200
AKWKIWGQVT CLLIWVVSLL VSLPQIIYSR VGHIDRLICQ FHNEAISTVV
210 220 230 240 250
LVLQMTLGFF LPLLTMILCY SGIIKTLLHA RNFQKHKSLK IIFLVVATFL
260 270 280 290 300
LTQTPFNIAM LIQWISWEYS TITSFQYVVL VTEAIAYLRA CLNPVLYAFV
310 320 330 340 350
GLKFRKNLWK LMKDISCLSR LGVSSQWKSS EDNSKTCSAS HNAETTSMFQ

L
Length:351
Mass (Da):40,368
Last modified:September 11, 2007 - v1
Checksum:i03585D6CE933E7F7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07071820 Genomic DNA No translation available.
DQ132631 mRNA Translation: AAZ66333.1
RefSeqiNP_001096057.1, NM_001102587.1
UniGeneiRn.217921

Genome annotation databases

EnsembliENSRNOT00000008294; ENSRNOP00000008294; ENSRNOG00000006319
GeneIDi100124593
KEGGirno:100124593
UCSCiRGD:1642118 rat

Similar proteinsi

Entry informationi

Entry nameiA7ISD5_RAT
AccessioniPrimary (citable) accession number: A7ISD5
Entry historyiIntegrated into UniProtKB/TrEMBL: September 11, 2007
Last sequence update: September 11, 2007
Last modified: May 23, 2018
This is version 92 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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