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A7IJ61 (A7IJ61_XANP2) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 32. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ferrochelatase HAMAP MF_00323 RuleBase RU000607
EC=4.99.1.1 HAMAP MF_00323 RuleBase RU000607
Alternative name(s):
Heme synthase HAMAP MF_00323
Protoheme ferro-lyase HAMAP MF_00323
Gene names
Name:hemH HAMAP MF_00323
Ordered Locus Names:Xaut_2814
OrganismXanthobacter autotrophicus (strain ATCC BAA-1158 / Py2) [Complete proteome] [HAMAP]
Taxonomic identifier78245 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Xanthobacteraceae › Xanthobacter

Protein attributes

Sequence length353 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the ferrous insertion into protoporphyrin IX By similarity. HAMAP MF_00323 RuleBase RU000607 SAAS SAAS001015

Catalytic activity

Protoheme + 2 H+ = protoporphyrin + Fe2+. HAMAP MF_00323 RuleBase RU000607 SAAS SAAS001015

Pathway

Porphyrin metabolism; protoheme biosynthesis; protoheme from protoporphyrin-IX: step 1/1. HAMAP MF_00323 RuleBase RU000607 SAAS SAAS001015

Subcellular location

Cytoplasm By similarity HAMAP MF_00323.

Sequence similarities

Belongs to the ferrochelatase family. HAMAP MF_00323 RuleBase RU004185

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding2221Iron By similarity HAMAP MF_00323
Metal binding3031Iron By similarity HAMAP MF_00323

Sequences

Sequence LengthMass (Da)Tools
A7IJ61 [UniParc].

Last modified September 11, 2007. Version 1.
Checksum: EF0C1123DDCE397F

FASTA35339,598
        10         20         30         40         50         60 
MTANVPAFSP DTTHLPPDHP KVAFGRIGVL IVNLGTPEAT DYWSMRAYLK EFLSDPRVIE 

        70         80         90        100        110        120 
VNRAVWWFVL NAIILTKRPG PKGRDYASIW NKERNEGPLK TITRDQAEQL AAQLSGLDSR 

       130        140        150        160        170        180 
IVVDFAMRYG KPPIAERLAA LQAQGCERIL LVPLYPQYSA ATSATVCDKA FDALKAMRWQ 

       190        200        210        220        230        240 
PTLRVAPPWH DDPVYIDALA TSLERHLAAL DFEPEVILAS FHGVPKSYLL KGDPYHCQCA 

       250        260        270        280        290        300 
KTARLLRARL DLDDKRFRLT FQSRFGRDEW LRPYTDATVK ALAESGVKRL AVVNPGFVAD 

       310        320        330        340        350 
CLETLEEIGV ENREIFEHHG GEKFAAIPCL NANAEGMRVL AHVVERELKG WVG

« Hide

References

[1]"Complete sequence of chromosome of Xanthobacter autotrophicus Py2."
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Sims D., Brettin T., Bruce D., Detter J.C., Han C., Tapia R., Brainard J., Schmutz J. expand/collapse author list , Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Ensigns S.A., Richardson P.
Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-1158 / Py2.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000781 Genomic DNA. Translation: ABS68054.1.
RefSeqYP_001417711.1. NC_009720.1.

3D structure databases

ProteinModelPortalA7IJ61.
ModBaseSearch...

Protein-protein interaction databases

STRINGA7IJ61.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5425160.
GenomeReviewsGene locus Xaut_2814 in contig CP000781_GR.
KEGGxau:Xaut_2814.
PATRIC24047723. VBIXanAut29526_3147.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0276.
HOGENOMHBG697135.
OMATIEEIGM.
ProtClustDBCLSK2459219.

Enzyme and pathway databases

BioCycXAUT78245:XAUT_2814-MONOMER.

Family and domain databases

HAMAPMF_00323. Ferrochelatase.
[Tree]
InterProIPR001015. Ferrochelatase.
IPR019772. Ferrochelatase_AS.
[Graphical view]
KOK01772.
PANTHERPTHR11108. Ferrochelatase. 1 hit.
PfamPF00762. Ferrochelatase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00109. HemH. 1 hit.
PROSITEPS00534. FERROCHELATASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA7IJ61_XANP2
AccessionPrimary (citable) accession number: A7IJ61
Entry history
Integrated into UniProtKB/TrEMBL: September 11, 2007
Last sequence update: September 11, 2007
Last modified: December 14, 2011
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info