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A7IGL7 (F16A1_XANP2) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 33. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Fructose-1,6-bisphosphatase class 1 1
Short name=FBPase class 1 1
EC=3.1.3.11
Alternative name(s):
D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 1
Gene names
Name:fbp1
Ordered Locus Names:Xaut_1915
OrganismXanthobacter autotrophicus (strain ATCC BAA-1158 / Py2) [Complete proteome] [HAMAP]
Taxonomic identifier78245 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Xanthobacteraceae › Xanthobacter

Protein attributes

Sequence length371 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate. HAMAP MF_01855

Cofactor

Binds 2 magnesium ions per subunit By similarity. HAMAP MF_01855

Pathway

Carbohydrate biosynthesis; gluconeogenesis. HAMAP MF_01855

Subunit structure

Homotetramer By similarity. HAMAP MF_01855

Subcellular location

Cytoplasm Potential HAMAP MF_01855.

Sequence similarities

Belongs to the FBPase class 1 family.

Ontologies

Keywords
   Biological processCarbohydrate metabolism
   Cellular componentCytoplasm
   LigandMagnesium
Metal-binding
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processcarbohydrate metabolic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionfructose 1,6-bisphosphate 1-phosphatase activity

Inferred from electronic annotation. Source: EC

metal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 371371Fructose-1,6-bisphosphatase class 1 1 HAMAP MF_01855
PRO_0000364748

Regions

Region137 – 1404Substrate binding By similarity
Region280 – 2823Substrate binding By similarity

Sites

Metal binding1151Magnesium 1 By similarity
Metal binding1341Magnesium 1 By similarity
Metal binding1341Magnesium 2 By similarity
Metal binding1361Magnesium 1; via carbonyl oxygen By similarity
Metal binding1371Magnesium 2 By similarity
Metal binding3001Magnesium 2 By similarity
Binding site2281Substrate By similarity

Sequences

Sequence LengthMass (Da)Tools
A7IGL7 [UniParc].

Last modified September 11, 2007. Version 1.
Checksum: 95EC62EAEB0044FD

FASTA37140,094
        10         20         30         40         50         60 
MTTRRTGRAE KTLRETTAMP TADHRAAPGI TLACALEEWA GEDARRRDVA ATLNALAAGT 

        70         80         90        100        110        120 
IQIARAIAEG PLAGDLARTL SSGEAGEGQK ALDIISNDMV IDALRKAPVA AVASEENDAP 

       130        140        150        160        170        180 
VLLDPEAPLL VAIDPLDGSS NIDTDISVGT IFAVFPHQDG TDAASVTAFL QNGRDMLAGG 

       190        200        210        220        230        240 
YVIYGPHTAL MLTVGAGTWH FALDRDGSFR LVNAAVRVKE DAAEFAINMS NYHHWDDPIR 

       250        260        270        280        290        300 
AYVDDCLAGR KGPREREFNM RWVASMVADA HRIFQRGGIY LYPGDGRKGY THGRLRLLYE 

       310        320        330        340        350        360 
AFPVAFLMEQ AQGSAIDGRS SILDLSATGV HQRVPFIFGS RDEVARAARY HLEPSGHGER 

       370 
SPLFARRGLF I

« Hide

References

[1]"Complete sequence of chromosome of Xanthobacter autotrophicus Py2."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Sims D., Brettin T., Bruce D., Detter J.C., Han C., Tapia R., Brainard J., Schmutz J. expand/collapse author list , Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Ensigns S.A., Richardson P.
Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-1158 / Py2.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000781 Genomic DNA. Translation: ABS67160.1.
RefSeqYP_001416817.1. NC_009720.1.

3D structure databases

ProteinModelPortalA7IGL7.
ModBaseSearch...

Protein-protein interaction databases

STRINGA7IGL7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5424513.
GenomeReviewsGene locus Xaut_1915 in contig CP000781_GR.
KEGGxau:Xaut_1915.
PATRIC24045901. VBIXanAut29526_2240.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0158.
HOGENOMHBG731261.
OMASEENDAP.

Enzyme and pathway databases

BioCycXAUT78245:XAUT_1915-MONOMER.

Family and domain databases

HAMAPMF_01855. FBPase_class1.
[Tree]
InterProIPR000146. FBPase_class-1/SBPase.
IPR020548. Fructose_bisphosphatase_AS.
[Graphical view]
KOK03841.
PANTHERPTHR11556. In_FB_phphtase. 1 hit.
PfamPF00316. FBPase. 1 hit.
[Graphical view]
PIRSFPIRSF000904. FBPtase_SBPase. 1 hit.
PRINTSPR00115. F16BPHPHTASE.
PROSITEPS00124. FBPASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameF16A1_XANP2
AccessionPrimary (citable) accession number: A7IGL7
Entry history
Integrated into UniProtKB/Swiss-Prot: March 3, 2009
Last sequence update: September 11, 2007
Last modified: January 25, 2012
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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