Reviewed, UniProtKB/Swiss-Prot A7IGL7 (F16A1_XANP2)

Names and origin

Protein names

Recommended name:
    Fructose-1,6-bisphosphatase class 1 1
      Short name=FBPase class 1 1
    EC=3.1.3.11
Alternative name(s):
    D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 1

Gene names

Name:	fbp1
Ordered Locus Names:	Xaut_1915

Organism

Xanthobacter autotrophicus (strain ATCC BAA-1158 / Py2) [Complete proteome] [HAMAP]

Taxonomic identifier

78245 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Xanthobacteraceae › Xanthobacter

Protein attributes

Sequence length	371 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate. HAMAP MF_01855
Cofactor	Binds 2 magnesium ions per subunit By similarity.
Pathway	Carbohydrate biosynthesis; gluconeogenesis. HAMAP MF_01855
Subunit structure	Homotetramer By similarity.
Subcellular location	Cytoplasm Potential.
Sequence similarities	Belongs to the FBPase class 1 family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism
Cellular component	Cytoplasm
Ligand	Magnesium Metal-binding
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	fructose 1,6-bisphosphate 1-phosphatase activity Inferred from electronic annotation. Source: HAMAP magnesium ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 371	371	Fructose-1,6-bisphosphatase class 1 1 HAMAP MF_01855		PRO_0000364748
Regions
	Region	137 – 140	4	Substrate binding By similarity
	Region	280 – 282	3	Substrate binding By similarity
Sites
	Metal binding	115	1	Magnesium 1 By similarity
	Metal binding	134	1	Magnesium 1 By similarity
	Metal binding	134	1	Magnesium 2 By similarity
	Metal binding	136	1	Magnesium 1; via carbonyl oxygen By similarity
	Metal binding	137	1	Magnesium 2 By similarity
	Metal binding	300	1	Magnesium 2 By similarity
	Binding site	228	1	Substrate By similarity

Sequences

	Sequence		Length	Mass (Da)
	A7IGL7-1 [UniParc]. Last modified September 11, 2007. Version 1. Checksum: 95EC62EAEB0044FD	FASTA	371	40,094
	10 20 30 40 50 60 MTTRRTGRAE KTLRETTAMP TADHRAAPGI TLACALEEWA GEDARRRDVA ATLNALAAGT 70 80 90 100 110 120 IQIARAIAEG PLAGDLARTL SSGEAGEGQK ALDIISNDMV IDALRKAPVA AVASEENDAP 130 140 150 160 170 180 VLLDPEAPLL VAIDPLDGSS NIDTDISVGT IFAVFPHQDG TDAASVTAFL QNGRDMLAGG 190 200 210 220 230 240 YVIYGPHTAL MLTVGAGTWH FALDRDGSFR LVNAAVRVKE DAAEFAINMS NYHHWDDPIR 250 260 270 280 290 300 AYVDDCLAGR KGPREREFNM RWVASMVADA HRIFQRGGIY LYPGDGRKGY THGRLRLLYE 310 320 330 340 350 360 AFPVAFLMEQ AQGSAIDGRS SILDLSATGV HQRVPFIFGS RDEVARAARY HLEPSGHGER 370 SPLFARRGLF I

References

[1]

"Complete sequence of chromosome of Xanthobacter autotrophicus Py2." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Sims D., Brettin T., Bruce D., Detter J.C., Han C., Tapia R., Brainard J., Schmutz J. , Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Ensigns S.A., Richardson P. Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000781 Genomic DNA. Translation: ABS67160.1.
RefSeq	YP_001416817.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A7IGL7.
Genome annotation databases
GeneID	5424513.
GenomeReviews	Gene locus Xaut_1915 in contig CP000781_GR.
KEGG	xau:Xaut_1915.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	SEENDAP.
Family and domain databases
HAMAP	MF_01855. [Tree]
InterPro	IPR000146. Fructose_bisphosphatase. IPR020548. Fructose_bisphosphatase_AS. [Graphical view]
PANTHER	PTHR11556. In_FB_phphtase. 1 hit.
Pfam	PF00316. FBPase. 1 hit. [Graphical view]
PRINTS	PR00115. F16BPHPHTASE.
ProDom	PD001491. In_FB_phphtase. 1 hit. [Graphical view] [Entries sharing at least one domain]
PROSITE	PS00124. FBPASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

F16A1_XANP2

Accession

Primary (citable) accession number: A7IGL7

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 3, 2009
Last sequence update:	September 11, 2007
Last modified:	November 3, 2009
This is version 17 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)