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A7IFV1 (A7IFV1_XANP2) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 33. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
GTP cyclohydrolase 1 HAMAP MF_00223
EC=3.5.4.16 HAMAP MF_00223
Alternative name(s):
GTP cyclohydrolase I HAMAP MF_00223
Gene names
Name:folE HAMAP MF_00223
Ordered Locus Names:Xaut_1649
OrganismXanthobacter autotrophicus (strain ATCC BAA-1158 / Py2) [Complete proteome] [HAMAP]
Taxonomic identifier78245 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Xanthobacteraceae › Xanthobacter

Protein attributes

Sequence length242 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

GTP + H2O = formate + 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)-dihydropteridine triphosphate. HAMAP MF_00223 SAAS SAAS001474

Pathway

Cofactor biosynthesis; 7,8-dihydroneopterin triphosphate biosynthesis; 7,8-dihydroneopterin triphosphate from GTP: step 1/1. HAMAP MF_00223 SAAS SAAS001474

Subunit structure

Homopolymer By similarity. HAMAP MF_00223

Sequence similarities

Belongs to the GTP cyclohydrolase I family. HAMAP MF_00223

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding1311Zinc By similarity HAMAP MF_00223
Metal binding1341Zinc By similarity HAMAP MF_00223
Metal binding2021Zinc By similarity HAMAP MF_00223

Sequences

Sequence LengthMass (Da)Tools
A7IFV1 [UniParc].

Last modified September 11, 2007. Version 1.
Checksum: B0E9AC8DAE666173

FASTA24226,935
        10         20         30         40         50         60 
MDAVVKLFKA QAENEERERK LKAEAKAASK AAARPDGAPP APKIHPPLPD GTPRPSRQEA 

        70         80         90        100        110        120 
EAAVRTLLAY IGEDPAREGL LDTPKRVVKA YDELFSGYGE DSEELLERTF GEIGTFDDFV 

       130        140        150        160        170        180 
LVRDIPFHSH CEHHMVPFVG KAHIAYFPVE RVVGLSKIAR VVDIFARRLQ TQEHLTSQIT 

       190        200        210        220        230        240 
TTLDEGLRPR GVAVMIEAEH MCMSMRGITK QGVSTLTTQF TGVFRDDPAE QVRFITLVRS 


KS

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References

[1]"Complete sequence of chromosome of Xanthobacter autotrophicus Py2."
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Sims D., Brettin T., Bruce D., Detter J.C., Han C., Tapia R., Brainard J., Schmutz J. expand/collapse author list , Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Ensigns S.A., Richardson P.
Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-1158 / Py2.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000781 Genomic DNA. Translation: ABS66894.1.
RefSeqYP_001416551.1. NC_009720.1.

3D structure databases

ProteinModelPortalA7IFV1.
ModBaseSearch...

Protein-protein interaction databases

STRINGA7IFV1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5423008.
GenomeReviewsGene locus Xaut_1649 in contig CP000781_GR.
KEGGxau:Xaut_1649.
PATRIC24045329. VBIXanAut29526_1960.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0302.
HOGENOMHBG370191.
OMACEAKHLC.
ProtClustDBPRK09347.

Enzyme and pathway databases

BioCycXAUT78245:XAUT_1649-MONOMER.

Family and domain databases

HAMAPMF_00223. FolE.
[Tree]
InterProIPR001474. GTP_CycHdrlase_I.
IPR020602. GTP_CycHdrlase_I/CN_OxRdtase.
IPR018234. GTP_CycHdrlase_I_CS.
[Graphical view]
KOK01495.
PANTHERPTHR11109. GTP_cyclohydro_I. 1 hit.
PfamPF01227. GTP_cyclohydroI. 1 hit.
[Graphical view]
TIGRFAMsTIGR00063. FolE. 1 hit.
PROSITEPS00859. GTP_CYCLOHYDROL_1_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA7IFV1_XANP2
AccessionPrimary (citable) accession number: A7IFV1
Entry history
Integrated into UniProtKB/TrEMBL: September 11, 2007
Last sequence update: September 11, 2007
Last modified: December 14, 2011
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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