A7IDG6 (A7IDG6_XANP2) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Error-prone DNA polymerase 1 HAMAP MF_01902
EC=2.7.7.7 HAMAP MF_01902

Gene names

Name:	dnaE2-1 HAMAP MF_01902
Ordered Locus Names:	Xaut_0808

Organism

Xanthobacter autotrophicus (strain ATCC BAA-1158 / Py2) [Complete proteome] [HAMAP]

Taxonomic identifier

78245 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Xanthobacteraceae › Xanthobacter

Protein attributes

Sequence length	1059 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase By similarity. HAMAP MF_01902
Catalytic activity	Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). HAMAP MF_01902 SAAS SAAS004013
Subcellular location	Cytoplasm By similarity HAMAP MF_01902 SAAS SAAS004013.
Sequence similarities	Belongs to the DNA polymerase type-C family. DnaE2 subfamily. HAMAP MF_01902

Ontologies

Keywords
Biological process	DNA damage DNA repair HAMAP MF_01902 SAAS SAAS004013 DNA replication HAMAP MF_01902 SAAS SAAS004013
Cellular component	Cytoplasm HAMAP MF_01902 SAAS SAAS004013
Molecular function	DNA-directed DNA polymerase HAMAP MF_01902 SAAS SAAS004013 Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA repair Inferred from electronic annotation. Source: HAMAP DNA replication Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	3'-5' exonuclease activity Inferred from electronic annotation. Source: InterPro DNA binding Inferred from electronic annotation. Source: InterPro DNA-directed DNA polymerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A7IDG6 [UniParc]. Last modified September 11, 2007. Version 1. Checksum: 7DEF15039EB27020	FASTA	1,059	118,224
	10 20 30 40 50 60 MSAPAYAELQ VTSHFSFLRG ASSAEELFAT AAAMGIGALA VTDRNTLAGI VRAHEAAKEA 70 80 90 100 110 120 GVRLIIGCRL DLVCGMSVLV YPTDWAAYSR LCRLLSLGKG RAGKARCHLE WDDLVAYGEG 130 140 150 160 170 180 LIVVLAPDLA DETCGLRLRR LRDAFGDRAY LGLTLRRRPN DQMRLWELST LAAGLGVPTV 190 200 210 220 230 240 VTNDVLFHEP GRRILQDVVT AIRHNVTVDA LGIRRERHAD RYLKAPGEMH RLFARWPEAL 250 260 270 280 290 300 ARTREIADRC RFSLDELRYQ YPEERDDPAL SPQETLERLT WEGAASRYPE GVPEEVTAAL 310 320 330 340 350 360 KHELALIGKL DYAPYFLTVN SIVRFARSRG ILRQGRGSAA NSAVCYVLGI TAIDPGRNDL 370 380 390 400 410 420 LFERFVSEER REPPDIDVDF EHERREEVIQ WVYEHYGRER AALTATVIRY RSKGALRDVG 430 440 450 460 470 480 KAMGLPEDLI QTLSGQLWGW SEAGVTEQQL RDLNLNPEDR RLRLTLELAA QLRGAPRHLS 490 500 510 520 530 540 QHPGGFVLTH DRLDDLVPIE PAAMEGRQII EWDKDDIDAL RFMKVDVLAL GMLSCMRRGL 550 560 570 580 590 600 DLLAEHKDIR LDLASIPAED PRTYAMIRKA DTLGTFQIES RAQMSMLPRL KPRTYYDLVV 610 620 630 640 650 660 QVAIVRPGPI QGDMVHPYLR RREGLEEVDY PRPELEKVLG KTLGVPLFQE QAMRVAIECA 670 680 690 700 710 720 GFTAGEADLL RKSMATFKHT GGVSKFRDRL ISGMIARGYE EEFAARTFQQ LEGFGSYGFP 730 740 750 760 770 780 ESHAASFALI AYASAWLKCW HPDVFCAALL NAQPMGFYAP AQIVRDAREH GVEVRPVCIN 790 800 810 820 830 840 ASRWDCTLEP TGDESRFAVR LGLRMVKGLA NAHAAAVVAA RGDETFTSVD DLWRRAGVPV 850 860 870 880 890 900 AALDQIAAAD GFRPAFGLAR REAQWAIKGL RDEELPLFAA ASEREGQTVP ELDEPAIALR 910 920 930 940 950 960 AMPAGREVVE DYGHIGLSLR RHPVSFLRED LARRRIVSCA EAMAAPDQRW LEAAGIVLVR 970 980 990 1000 1010 1020 QRPGSANGVM FITLEDETGI ANLVVWQKVF ERYRRVILSS SMIAVRGRVQ REGEVVHLVA 1030 1040 1050 HRIVDLSRDL ASVGQREMAT AEQQGPEAGG VRVKARDFR

References

[1]

"Complete sequence of chromosome of Xanthobacter autotrophicus Py2." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Sims D., Brettin T., Bruce D., Detter J.C., Han C., Tapia R., Brainard J., Schmutz J. , Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Ensigns S.A., Richardson P. Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-1158 / Py2.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000781 Genomic DNA. Translation: ABS66059.1.
RefSeq	YP_001415716.1. NC_009720.1.
3D structure databases
ProteinModelPortal	A7IDG6.
ModBase	Search...
Protein-protein interaction databases
STRING	A7IDG6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5420956.
GenomeReviews	Gene locus Xaut_0808 in contig CP000781_GR.
KEGG	xau:Xaut_0808.
PATRIC	24043559. VBIXanAut29526_1085.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0587.
HOGENOM	HBG734490.
OMA	ADYCANG.
ProtClustDB	CLSK881842.
Enzyme and pathway databases
BioCyc	XAUT78245:XAUT_0808-MONOMER.
Family and domain databases
HAMAP	MF_01902. DNApol_error_prone. [Tree]
InterPro	IPR011708. DNA_pol3_alpha. IPR023073. DNA_pol_error_prone. IPR004365. NA-bd_OB_tRNA-helicase. IPR004013. PHP_C. IPR003141. Pol/His_phosphatase_N. IPR016195. Pol/histidinol_Pase-like. IPR004805. PolC_alpha. [Graphical view]
KO	K14162.
Pfam	PF07733. DNA_pol3_alpha. 1 hit. PF02811. PHP. 1 hit. PF01336. tRNA_anti. 1 hit. [Graphical view]
SMART	SM00481. POLIIIAc. 1 hit. [Graphical view]
SUPFAM	SSF89550. PHP-like. 1 hit.
TIGRFAMs	TIGR00594. Polc. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A7IDG6_XANP2

Accession

Primary (citable) accession number: A7IDG6

Entry history

Integrated into UniProtKB/TrEMBL:	September 11, 2007
Last sequence update:	September 11, 2007
Last modified:	December 14, 2011
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)