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Protein

Cell division protein FtsZ

Gene

ftsZ

Organism
Xanthobacter autotrophicus (strain ATCC BAA-1158 / Py2)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei142GTPUniRule annotation1
Binding sitei146GTPUniRule annotation1
Binding sitei190GTPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi24 – 28GTPUniRule annotation5
Nucleotide bindingi111 – 113GTPUniRule annotation3

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processCell cycle, Cell division, SeptationUniRule annotation
LigandGTP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cell division protein FtsZUniRule annotation
Gene namesi
Name:ftsZUniRule annotation
Ordered Locus Names:Xaut_0328Imported
OrganismiXanthobacter autotrophicus (strain ATCC BAA-1158 / Py2)Imported
Taxonomic identifieri78245 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesXanthobacteraceaeXanthobacter
Proteomesi
  • UP000002417 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi78245.Xaut_0328.

Structurei

3D structure databases

ProteinModelPortaliA7IC43.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini16 – 208TubulinInterPro annotationAdd BLAST193
Domaini210 – 328Tubulin_CInterPro annotationAdd BLAST119

Sequence similaritiesi

Belongs to the FtsZ family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CDK. Bacteria.
COG0206. LUCA.
HOGENOMiHOG000049094.
KOiK03531.
OMAiRAVMREM.
OrthoDBiPOG091H02KK.

Family and domain databases

CDDicd02201. FtsZ_type1. 1 hit.
Gene3Di3.30.1330.20. 1 hit.
3.40.50.1440. 1 hit.
HAMAPiMF_00909. FtsZ. 1 hit.
InterProiView protein in InterPro
IPR000158. Cell_div_FtsZ.
IPR017844. Cell_div_FtsZ_C.
IPR020805. Cell_div_FtsZ_CS.
IPR024757. FtsZ_C.
IPR008280. Tub_FtsZ_C.
IPR018316. Tubulin/FtsZ_2-layer-sand-dom.
IPR003008. Tubulin_FtsZ_GTPase.
PfamiView protein in Pfam
PF12327. FtsZ_C. 1 hit.
PF00091. Tubulin. 1 hit.
PRINTSiPR00423. CELLDVISFTSZ.
SMARTiView protein in SMART
SM00864. Tubulin. 1 hit.
SM00865. Tubulin_C. 1 hit.
SUPFAMiSSF52490. SSF52490. 1 hit.
SSF55307. SSF55307. 1 hit.
TIGRFAMsiTIGR00065. ftsZ. 1 hit.
TIGR03483. FtsZ_alphas_C. 1 hit.
PROSITEiView protein in PROSITE
PS01134. FTSZ_1. 1 hit.
PS01135. FTSZ_2. 1 hit.

Sequencei

Sequence statusi: Complete.

A7IC43-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTINLQMPDI RELRPRITVF GVGGAGGNAV NNMITAGLHG VEFVVANTDA
60 70 80 90 100
QALSLTKAER VVQMGVAVTE GLGAGSQPEV GRAAAEEVID EIRDHLSGSH
110 120 130 140 150
MVFITAGMGG GTGTGAAPVV ARAARELGIL TVGVVTKPFH FEGARRMRVA
160 170 180 190 200
EHGISELQKS VDTLIVIPNQ NLFRVANEKT TFADAFAMAD QVLYSGVACI
210 220 230 240 250
TDLMVKEGLI NLDFADVRAV MRDMGKAMMG TGEASGDKRA IQAAEAAIAN
260 270 280 290 300
PLLDETSMRG AGGLLISITG GKDMTLFEVD EAATRIREEV DPDANIILGA
310 320 330 340 350
TFDEVLDGII RVSVVATGID PAVIPDQVSP GAERFPDLAG RKISNAGRAA
360 370 380 390 400
VEATREAQIR TAVASISAED LIGMEDAQAQ AAQAHAAYAP QSFAPAAPAP
410 420 430 440 450
QQAVAIDDVT IRAAAPKPSY FAEPEPAAPP APMVEDEFAP YIPPQGQRPR
460 470 480 490 500
SQRMPRVDEL PLPGQNQIRA QRGEPPVEQP QPDKKRMTLL QRLAHVGRRE
510 520 530 540 550
EEPEPQRRDQ PSMRAPERRP VEPRQEARPE PRQETRDVRP TLPGRAGEPP
560 570 580 590
VSEFAKRPPA RPAAEVPSRP GPHHEDDQLE IPAFLRRQAN
Length:590
Mass (Da):63,117
Last modified:September 11, 2007 - v1
Checksum:iE93F1496FA9F0291
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000781 Genomic DNA. Translation: ABS65586.1.
RefSeqiWP_011995986.1. NC_009720.1.

Genome annotation databases

EnsemblBacteriaiABS65586; ABS65586; Xaut_0328.
KEGGixau:Xaut_0328.

Similar proteinsi

Entry informationi

Entry nameiA7IC43_XANP2
AccessioniPrimary (citable) accession number: A7IC43
Entry historyiIntegrated into UniProtKB/TrEMBL: September 11, 2007
Last sequence update: September 11, 2007
Last modified: September 27, 2017
This is version 75 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported