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A7IAR4 (TF2B_METB6) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 49. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Transcription initiation factor IIB

Short name=TFIIB
Gene names
Name:tfb
Ordered Locus Names:Mboo_2311
OrganismMethanoregula boonei (strain 6A8) [Complete proteome] [HAMAP]
Taxonomic identifier456442 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaMethanomicrobiaMethanomicrobialesMethanoregulaceaeMethanoregula

Protein attributes

Sequence length334 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB) By similarity. HAMAP-Rule MF_00383

Cofactor

Binds 1 zinc ion per subunit By similarity. HAMAP-Rule MF_00383

Sequence similarities

Belongs to the TFIIB family.

Contains 1 TFIIB-type zinc finger.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 334334Transcription initiation factor IIB HAMAP-Rule MF_00383
PRO_1000080107

Regions

Repeat151 – 234841 HAMAP-Rule MF_00383
Repeat245 – 326822 HAMAP-Rule MF_00383
Zinc finger34 – 6532TFIIB-type HAMAP-Rule MF_00383

Sites

Metal binding381Zinc By similarity
Metal binding411Zinc By similarity
Metal binding571Zinc By similarity
Metal binding601Zinc By similarity

Sequences

Sequence LengthMass (Da)Tools
A7IAR4 [UniParc].

Last modified September 11, 2007. Version 1.
Checksum: A6C45EFF371AF499

FASTA33437,847
        10         20         30         40         50         60 
MQEVEKLKLL QSEREALKSR IKVKEQEKKA ENHTETVCPE CGGRQLVHDY ERAELVCQSC 

        70         80         90        100        110        120 
GLVIDDDFID RGPEWRAFDH DQRMKRSRVG APMTFTIHDK GLSTMIDWRN RDSYGRAISS 

       130        140        150        160        170        180 
KNRAQLYRLR KWQRRIRVSN ATERNLAFAL SELDRMASAL GLPRNVRETA AVVYRDAVDK 

       190        200        210        220        230        240 
NLIRGRSIEG VAAAALYAAC RQCSVPRTLD EIAEVSRVSR KEIGRTYRFI SRELGLKLLP 

       250        260        270        280        290        300 
TSPIDYVPRF CSGLTLKGEV QSRAVEILRQ AGERELTSGR GPTGVAAAAI YISSILGGER 

       310        320        330 
RTQREVAEVA GVTEVTIRNR YKELAEKLDI EIIL 

« Hide

References

[1]"Complete sequence of Candidatus Methanoregula boonei 6A8."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Meincke L., Brettin T., Bruce D., Detter J.C., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Kyrpides N., Kim E., Zinder S., Richardson P.
Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 6A8.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000780 Genomic DNA. Translation: ABS56825.1.
RefSeqYP_001405468.1. NC_009712.1.

3D structure databases

ProteinModelPortalA7IAR4.
SMRA7IAR4. Positions 138-332.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING456442.Mboo_2311.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABS56825; ABS56825; Mboo_2311.
GeneID5409810.
KEGGmbn:Mboo_2311.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1405.
HOGENOMHOG000108633.
KOK03124.
OMAWRAFDHD.

Enzyme and pathway databases

BioCycMBOO456442:GH2T-2365-MONOMER.

Family and domain databases

Gene3D1.10.472.10. 2 hits.
HAMAPMF_00383. TF2B_arch.
InterProIPR013763. Cyclin-like.
IPR000812. TFIIB.
IPR023484. TFIIB_arc.
IPR023486. TFIIB_CS.
IPR013150. TFIIB_cyclin.
IPR013137. Znf_TFIIB.
[Graphical view]
PANTHERPTHR11618. PTHR11618. 1 hit.
PfamPF08271. TF_Zn_Ribbon. 1 hit.
PF00382. TFIIB. 2 hits.
[Graphical view]
PRINTSPR00685. TIFACTORIIB.
SMARTSM00385. CYCLIN. 2 hits.
[Graphical view]
SUPFAMSSF47954. SSF47954. 2 hits.
PROSITEPS00782. TFIIB. 2 hits.
PS51134. ZF_TFIIB. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameTF2B_METB6
AccessionPrimary (citable) accession number: A7IAR4
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: September 11, 2007
Last modified: May 14, 2014
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families