A7I9J3 (RNP4_METB6) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribonuclease P protein component 4
Short name=RNase P component 4
EC=3.1.26.5

Gene names

Name:	rnp4
Ordered Locus Names:	Mboo_1889

Organism

Methanoregula boonei (strain 6A8) [Complete proteome] [HAMAP]

Taxonomic identifier

456442 [NCBI]

Taxonomic lineage

cellular organisms › Archaea › Euryarchaeota › Methanomicrobia › Methanomicrobiales › Methanoregulaceae › Methanoregula › Methanoregula boonei

Protein attributes

Sequence length	104 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends By similarity. HAMAP-Rule MF_00757
Catalytic activity	Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor. HAMAP-Rule MF_00757
Subunit structure	Consists of a catalytic RNA component and at least 4 protein subunits Potential.
Sequence similarities	Belongs to the eukaryotic/archaeal RNase P protein component 4 family.

Ontologies

Keywords
Biological process	tRNA processing
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	tRNA 5'-leader removal Inferred from electronic annotation. Source: HAMAP
Molecular_function	ribonuclease P activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 104	104	Ribonuclease P protein component 4 HAMAP-Rule MF_00757		PRO_1000194597

Sequences

	Sequence		Length	Mass (Da)
	A7I9J3 [UniParc]. Last modified September 11, 2007. Version 1. Checksum: A8C72912B9B80CED	FASTA	104	12,378
	10 20 30 40 50 60 MKDKKRPPSV KPLARERIAV LFSEAEKIFH ENPGYSDRYV ALARKISMKE RVRIDHEYRR 70 80 90 100 RFCHHCSRYL VPGANMRVRV HHGWVAVTCL GCKKTTRYRV ERTP

References

[1]

"Complete sequence of Candidatus Methanoregula boonei 6A8." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Meincke L., Brettin T., Bruce D., Detter J.C., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M. , Hauser L., Kyrpides N., Kim E., Zinder S., Richardson P. Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 6A8.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000780 Genomic DNA. Translation: ABS56404.1.
RefSeq	YP_001405047.1. NC_009712.1.
3D structure databases
ProteinModelPortal	A7I9J3.
ModBase	Search...
Protein-protein interaction databases
STRING	456442.Mboo_1889.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABS56404; ABS56404; Mboo_1889.
GeneID	5410731.
KEGG	mbn:Mboo_1889.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2023.
HOGENOM	HOG000230709.
KO	K03540.
OMA	RVIITCL.
ProtClustDB	CLSK965465.
Enzyme and pathway databases
BioCyc	MBOO456442:GH2T-1942-MONOMER.
Family and domain databases
HAMAP	MF_00757. RNase_P_4.
InterPro	IPR016432. RNase_P_comp-4. IPR007175. Rpr2. [Graphical view]
Pfam	PF04032. Rpr2. 1 hit. [Graphical view]
PIRSF	PIRSF004878. RNase_P_4. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RNP4_METB6

Accession

Primary (citable) accession number: A7I9J3

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	September 11, 2007
Last modified:	May 1, 2013
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program