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A7I9J3

- RNP4_METB6

UniProt

A7I9J3 - RNP4_METB6

Protein

Ribonuclease P protein component 4

Gene

rnp4

Organism
Methanoregula boonei (strain 6A8)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
  1. Functioni

    Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.UniRule annotation

    Catalytic activityi

    Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.UniRule annotation

    Cofactori

    Binds 1 zinc ion per subunit.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi63 – 631ZincUniRule annotation
    Metal bindingi66 – 661ZincUniRule annotation
    Metal bindingi89 – 891ZincUniRule annotation
    Metal bindingi92 – 921ZincUniRule annotation

    GO - Molecular functioni

    1. ribonuclease P activity Source: UniProtKB-HAMAP
    2. zinc ion binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. tRNA 5'-leader removal Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Endonuclease, Hydrolase, Nuclease

    Keywords - Biological processi

    tRNA processing

    Keywords - Ligandi

    Metal-binding, Zinc

    Enzyme and pathway databases

    BioCyciMBOO456442:GH2T-1925-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Ribonuclease P protein component 4UniRule annotation (EC:3.1.26.5UniRule annotation)
    Short name:
    RNase P component 4UniRule annotation
    Alternative name(s):
    Rpp21UniRule annotation
    Gene namesi
    Name:rnp4UniRule annotation
    Ordered Locus Names:Mboo_1889
    OrganismiMethanoregula boonei (strain 6A8)
    Taxonomic identifieri456442 [NCBI]
    Taxonomic lineageiArchaeaEuryarchaeotaMethanomicrobiaMethanomicrobialesMethanoregulaceaeMethanoregula
    ProteomesiUP000002408: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell
    2. ribonuclease P complex Source: UniProtKB-HAMAP

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 104104Ribonuclease P protein component 4PRO_1000194597Add
    BLAST

    Interactioni

    Subunit structurei

    Consists of a catalytic RNA component and at least 4-5 protein subunits.UniRule annotation

    Protein-protein interaction databases

    STRINGi456442.Mboo_1889.

    Structurei

    3D structure databases

    ProteinModelPortaliA7I9J3.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the eukaryotic/archaeal RNase P protein component 4 family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG2023.
    HOGENOMiHOG000230709.
    KOiK03540.
    OMAiGECGHVM.

    Family and domain databases

    HAMAPiMF_00757. RNase_P_4.
    InterProiIPR016432. RNase_P_comp-4.
    IPR007175. Rpr2.
    [Graphical view]
    PANTHERiPTHR14742. PTHR14742. 1 hit.
    PfamiPF04032. Rpr2. 1 hit.
    [Graphical view]
    PIRSFiPIRSF004878. RNase_P_4. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    A7I9J3-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKDKKRPPSV KPLARERIAV LFSEAEKIFH ENPGYSDRYV ALARKISMKE    50
    RVRIDHEYRR RFCHHCSRYL VPGANMRVRV HHGWVAVTCL GCKKTTRYRV 100
    ERTP 104
    Length:104
    Mass (Da):12,378
    Last modified:September 11, 2007 - v1
    Checksum:iA8C72912B9B80CED
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000780 Genomic DNA. Translation: ABS56404.1.
    RefSeqiWP_012107457.1. NC_009712.1.
    YP_001405047.1. NC_009712.1.

    Genome annotation databases

    EnsemblBacteriaiABS56404; ABS56404; Mboo_1889.
    GeneIDi5410731.
    KEGGimbn:Mboo_1889.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000780 Genomic DNA. Translation: ABS56404.1 .
    RefSeqi WP_012107457.1. NC_009712.1.
    YP_001405047.1. NC_009712.1.

    3D structure databases

    ProteinModelPortali A7I9J3.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 456442.Mboo_1889.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABS56404 ; ABS56404 ; Mboo_1889 .
    GeneIDi 5410731.
    KEGGi mbn:Mboo_1889.

    Phylogenomic databases

    eggNOGi COG2023.
    HOGENOMi HOG000230709.
    KOi K03540.
    OMAi GECGHVM.

    Enzyme and pathway databases

    BioCyci MBOO456442:GH2T-1925-MONOMER.

    Family and domain databases

    HAMAPi MF_00757. RNase_P_4.
    InterProi IPR016432. RNase_P_comp-4.
    IPR007175. Rpr2.
    [Graphical view ]
    PANTHERi PTHR14742. PTHR14742. 1 hit.
    Pfami PF04032. Rpr2. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF004878. RNase_P_4. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 6A8.

    Entry informationi

    Entry nameiRNP4_METB6
    AccessioniPrimary (citable) accession number: A7I9J3
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 14, 2009
    Last sequence update: September 11, 2007
    Last modified: October 1, 2014
    This is version 41 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3