ID   A7I8V8_METB6            Unreviewed;       687 AA.
AC   A7I8V8;
DT   11-SEP-2007, integrated into UniProtKB/TrEMBL.
DT   11-SEP-2007, sequence version 1.
DT   27-MAR-2024, entry version 82.
DE   SubName: Full=Stage II sporulation E family protein {ECO:0000313|EMBL:ABS56169.1};
GN   OrderedLocusNames=Mboo_1652 {ECO:0000313|EMBL:ABS56169.1};
OS   Methanoregula boonei (strain DSM 21154 / JCM 14090 / 6A8).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanomicrobiales; Methanoregulaceae; Methanoregula.
OX   NCBI_TaxID=456442 {ECO:0000313|EMBL:ABS56169.1, ECO:0000313|Proteomes:UP000002408};
RN   [1] {ECO:0000313|Proteomes:UP000002408}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 21154 / JCM 14090 / 6A8
RC   {ECO:0000313|Proteomes:UP000002408};
RX   PubMed=25998264; DOI=10.1099/mic.0.000117;
RA   Braeuer S., Cadillo-Quiroz H., Kyrpides N., Woyke T., Goodwin L.,
RA   Detter C., Podell S., Yavitt J.B., Zinder S.H.;
RT   "Genome of Methanoregula boonei 6A8 reveals adaptations to oligotrophic
RT   peatland environments.";
RL   Microbiology 161:1572-1581(2015).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; CP000780; ABS56169.1; -; Genomic_DNA.
DR   AlphaFoldDB; A7I8V8; -.
DR   STRING; 456442.Mboo_1652; -.
DR   KEGG; mbn:Mboo_1652; -.
DR   eggNOG; arCOG02362; Archaea.
DR   eggNOG; arCOG06893; Archaea.
DR   HOGENOM; CLU_020306_1_0_2; -.
DR   Proteomes; UP000002408; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   CDD; cd06225; HAMP; 1.
DR   CDD; cd12912; PDC2_MCP_like; 1.
DR   Gene3D; 6.10.340.10; -; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 2.
DR   Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR   InterPro; IPR033479; dCache_1.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR036457; PPM-type-like_dom_sf.
DR   InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR   PANTHER; PTHR43156; STAGE II SPORULATION PROTEIN E-RELATED; 1.
DR   Pfam; PF02743; dCache_1; 1.
DR   Pfam; PF00672; HAMP; 1.
DR   Pfam; PF07228; SpoIIE; 1.
DR   SMART; SM00304; HAMP; 1.
DR   SMART; SM00331; PP2C_SIG; 1.
DR   SUPFAM; SSF158472; HAMP domain-like; 1.
DR   SUPFAM; SSF81606; PP2C-like; 1.
DR   PROSITE; PS50885; HAMP; 1.
DR   PROSITE; PS51746; PPM_2; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002408};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT   DOMAIN          383..435
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          471..686
FT                   /note="PPM-type phosphatase"
FT                   /evidence="ECO:0000259|PROSITE:PS51746"
SQ   SEQUENCE   687 AA;  73509 MW;  7FD65E9C0C62FD6E CRC64;
     MALALTGYFA FFAITRVGSY AQGSSEALGM GMADQSSAAL LSLGEEYLQR ITADQANVTD
     TLFADTDTDT EMEILAAQTA ELKRNSPVKA ITPTYLATQP PSDPMAGAVL VFAQNATVTP
     ESQEARTLAG LADSLKGVYD SDEDMASVYI GTASGMMLYY PGQGNFPKDY DPRTRQWFTD
     AEASPEIVWS DAPYVDAGGN GLVMTSSEDI TGPAYGNWVI GSDVKTDTIN EDFIGKTLGG
     NGYAVLINQE GTIISQPGLS AGNQTWNKPF TQKNVLSGSA PDLRAVVTNM TAGKTGIGTV
     NFSGTETYVA YAPVRSMNWS LAVSIPVSQI TEPVQEFTGK IEDATRDTGT QITAQTDWLK
     EVFAILFVVI LLVVLLVSIE LSRVITRPVE QLKEGAAAIG EGDLAFRVNI QSGDEFEDLA
     RSFNVMAGAL QENIENLRRT TAEKERYAKE LEIARSIQTS FLPEKMPDIP GYDISAVMIP
     AMEVGGDFYD IIPAADGKWA FVIADVSGKG VSAALFMAMS RTLLRAGLEN ASDLSCAIGT
     ANQVISRNAP SCMFVTVFTA LLDLPARTFT CINAGHNPPL LVRGKSGETV FFHEGGVALG
     VQPEIKSVQE CVQLQSGDLV ILYTDGVTEA FDAAYTPFGE DRLVEIAKEC SNLPADRVRE
     GIIAGIRAFT GPVPQSDDIT LVVIRVL
//