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Protein

Adenine deaminase

Gene

ade

Organism
Methanoregula boonei (strain DSM 21154 / JCM 14090 / 6A8)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

Adenine + H2O = hypoxanthine + NH3.UniRule annotation

Cofactori

Mn2+UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase
LigandManganese

Enzyme and pathway databases

BioCyciMBOO456442:G1G9N-1680-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Adenine deaminaseUniRule annotation (EC:3.5.4.2UniRule annotation)
Short name:
AdenaseUniRule annotation
Short name:
Adenine aminaseUniRule annotation
Gene namesi
Name:adeUniRule annotation
Ordered Locus Names:Mboo_1575
OrganismiMethanoregula boonei (strain DSM 21154 / JCM 14090 / 6A8)
Taxonomic identifieri456442 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanomicrobiaMethanomicrobialesMethanoregulaceaeMethanoregula
Proteomesi
  • UP000002408 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003185501 – 558Adenine deaminaseAdd BLAST558

Interactioni

Protein-protein interaction databases

STRINGi456442.Mboo_1575

Structurei

3D structure databases

ProteinModelPortaliA7I8N1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG00693 Archaea
COG1001 LUCA
HOGENOMiHOG000276949
KOiK01486
OMAiHEIANVM
OrthoDBiPOG093Z030C

Family and domain databases

CDDicd01295 AdeC, 1 hit
Gene3Di2.30.40.10, 2 hits
HAMAPiMF_01518 Adenine_deamin, 1 hit
InterProiView protein in InterPro
IPR006679 Adenine_deam
IPR026912 Adenine_deam_C
IPR006680 Amidohydro-rel
IPR011059 Metal-dep_hydrolase_composite
IPR032466 Metal_Hydrolase
PfamiView protein in Pfam
PF13382 Adenine_deam_C, 1 hit
PF01979 Amidohydro_1, 2 hits
SUPFAMiSSF51338 SSF51338, 2 hits
SSF51556 SSF51556, 1 hit
TIGRFAMsiTIGR01178 ade, 1 hit

Sequencei

Sequence statusi: Complete.

A7I8N1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDAPPLHANL IPAARGTEPA DLVLKNAMLF DAFSCSWEEG DLAIKDGIIV
60 70 80 90 100
GTGRSYRGIR ERDLGGALVV PGLIDAHVHI ESSLLVPQEY AHLVAAHGTT
110 120 130 140 150
TVIADPHEIA NIAGKEGIEY MLACRAGLPV DILYMLPSCV PATPADVGGA
160 170 180 190 200
VLDAGDLAGF PGRDGILGLG EMMNVPGVLG GDPGVLAKLV LSRIRDGHAP
210 220 230 240 250
HLSGPDLNAY LLSGPDSDHE CTTASEAKEK LRCGMYLFVR EGSTEKNIAA
260 270 280 290 300
LVPVVTPYTV SRCSFCTDDC HADLLAHSGH IDRCIRTAVA GGLEPELALR
310 320 330 340 350
MATLSPAERF SLPDRGALAP GRRADFCIVD DPRHFAVKET YSRGRPVAEY
360 370 380 390 400
AAPQARPPVF AALRCTVPSR DQIRLFGTGR ARVIGLVPGQ ILTESLTFDL
410 420 430 440 450
DAAALPDISR DLLKLVVCNR YGKGSVGTGI VHGFGFKDGA IAASISHDAH
460 470 480 490 500
NIVAAGTGDE VILSALTAVI RAGGGMAAVH KKDVTVLPLD CAGLMSTHPA
510 520 530 540 550
REVIAGLDAL SAATRRIGGI DDPFMYLSFL ALTVIPALRL TDRGLFDAVA

FRDVPVFP
Length:558
Mass (Da):58,705
Last modified:September 11, 2007 - v1
Checksum:iA7B500DFA84FA4F3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000780 Genomic DNA Translation: ABS56092.1
RefSeqiWP_012107135.1, NC_009712.1

Genome annotation databases

EnsemblBacteriaiABS56092; ABS56092; Mboo_1575
GeneIDi5410587
KEGGimbn:Mboo_1575

Similar proteinsi

Entry informationi

Entry nameiADEC_METB6
AccessioniPrimary (citable) accession number: A7I8N1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: September 11, 2007
Last modified: March 28, 2018
This is version 63 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health