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Protein

Adenine deaminase

Gene

ade

Organism
Methanoregula boonei (strain 6A8)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Adenine + H2O = hypoxanthine + NH3.UniRule annotation

Cofactori

Mn2+UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Ligandi

Manganese

Enzyme and pathway databases

BioCyciMBOO456442:GH2T-1604-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Adenine deaminaseUniRule annotation (EC:3.5.4.2UniRule annotation)
Short name:
AdenaseUniRule annotation
Short name:
Adenine aminaseUniRule annotation
Gene namesi
Name:adeUniRule annotation
Ordered Locus Names:Mboo_1575
OrganismiMethanoregula boonei (strain 6A8)
Taxonomic identifieri456442 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanomicrobiaMethanomicrobialesMethanoregulaceaeMethanoregula
Proteomesi
  • UP000002408 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 558558Adenine deaminasePRO_0000318550Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi456442.Mboo_1575.

Structurei

3D structure databases

ProteinModelPortaliA7I8N1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the adenine deaminase family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG00693. Archaea.
COG1001. LUCA.
HOGENOMiHOG000276949.
KOiK01486.
OMAiCTDDKHL.

Family and domain databases

Gene3Di2.30.40.10. 2 hits.
HAMAPiMF_01518. Adenine_deamin.
InterProiIPR006679. Adenine_deam.
IPR026912. Adenine_deam_C.
IPR006680. Amidohydro-rel.
IPR011059. Metal-dep_hydrolase_composite.
IPR032466. Metal_Hydrolase.
[Graphical view]
PfamiPF13382. Adenine_deam_C. 1 hit.
PF01979. Amidohydro_1. 2 hits.
[Graphical view]
SUPFAMiSSF51338. SSF51338. 2 hits.
SSF51556. SSF51556. 1 hit.
TIGRFAMsiTIGR01178. ade. 1 hit.

Sequencei

Sequence statusi: Complete.

A7I8N1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDAPPLHANL IPAARGTEPA DLVLKNAMLF DAFSCSWEEG DLAIKDGIIV
60 70 80 90 100
GTGRSYRGIR ERDLGGALVV PGLIDAHVHI ESSLLVPQEY AHLVAAHGTT
110 120 130 140 150
TVIADPHEIA NIAGKEGIEY MLACRAGLPV DILYMLPSCV PATPADVGGA
160 170 180 190 200
VLDAGDLAGF PGRDGILGLG EMMNVPGVLG GDPGVLAKLV LSRIRDGHAP
210 220 230 240 250
HLSGPDLNAY LLSGPDSDHE CTTASEAKEK LRCGMYLFVR EGSTEKNIAA
260 270 280 290 300
LVPVVTPYTV SRCSFCTDDC HADLLAHSGH IDRCIRTAVA GGLEPELALR
310 320 330 340 350
MATLSPAERF SLPDRGALAP GRRADFCIVD DPRHFAVKET YSRGRPVAEY
360 370 380 390 400
AAPQARPPVF AALRCTVPSR DQIRLFGTGR ARVIGLVPGQ ILTESLTFDL
410 420 430 440 450
DAAALPDISR DLLKLVVCNR YGKGSVGTGI VHGFGFKDGA IAASISHDAH
460 470 480 490 500
NIVAAGTGDE VILSALTAVI RAGGGMAAVH KKDVTVLPLD CAGLMSTHPA
510 520 530 540 550
REVIAGLDAL SAATRRIGGI DDPFMYLSFL ALTVIPALRL TDRGLFDAVA

FRDVPVFP
Length:558
Mass (Da):58,705
Last modified:September 11, 2007 - v1
Checksum:iA7B500DFA84FA4F3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000780 Genomic DNA. Translation: ABS56092.1.
RefSeqiWP_012107135.1. NC_009712.1.

Genome annotation databases

EnsemblBacteriaiABS56092; ABS56092; Mboo_1575.
GeneIDi5410587.
KEGGimbn:Mboo_1575.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000780 Genomic DNA. Translation: ABS56092.1.
RefSeqiWP_012107135.1. NC_009712.1.

3D structure databases

ProteinModelPortaliA7I8N1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi456442.Mboo_1575.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABS56092; ABS56092; Mboo_1575.
GeneIDi5410587.
KEGGimbn:Mboo_1575.

Phylogenomic databases

eggNOGiarCOG00693. Archaea.
COG1001. LUCA.
HOGENOMiHOG000276949.
KOiK01486.
OMAiCTDDKHL.

Enzyme and pathway databases

BioCyciMBOO456442:GH2T-1604-MONOMER.

Family and domain databases

Gene3Di2.30.40.10. 2 hits.
HAMAPiMF_01518. Adenine_deamin.
InterProiIPR006679. Adenine_deam.
IPR026912. Adenine_deam_C.
IPR006680. Amidohydro-rel.
IPR011059. Metal-dep_hydrolase_composite.
IPR032466. Metal_Hydrolase.
[Graphical view]
PfamiPF13382. Adenine_deam_C. 1 hit.
PF01979. Amidohydro_1. 2 hits.
[Graphical view]
SUPFAMiSSF51338. SSF51338. 2 hits.
SSF51556. SSF51556. 1 hit.
TIGRFAMsiTIGR01178. ade. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 6A8.

Entry informationi

Entry nameiADEC_METB6
AccessioniPrimary (citable) accession number: A7I8N1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: September 11, 2007
Last modified: November 11, 2015
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.