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Protein

5'-nucleotidase SurE

Gene

surE

Organism
Methanoregula boonei (strain 6A8)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.UniRule annotation

Catalytic activityi

A 5'-ribonucleotide + H2O = a ribonucleoside + phosphate.UniRule annotation

Cofactori

a divalent metal cationUniRule annotationNote: Binds 1 divalent metal cation per subunit.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi10 – 101Divalent metal cationUniRule annotation
Metal bindingi11 – 111Divalent metal cationUniRule annotation
Metal bindingi41 – 411Divalent metal cationUniRule annotation
Metal bindingi95 – 951Divalent metal cationUniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Ligandi

Metal-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciMBOO456442:GH2T-939-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
5'-nucleotidase SurEUniRule annotation (EC:3.1.3.5UniRule annotation)
Alternative name(s):
Nucleoside 5'-monophosphate phosphohydrolaseUniRule annotation
Gene namesi
Name:surEUniRule annotation
Ordered Locus Names:Mboo_0919
OrganismiMethanoregula boonei (strain 6A8)
Taxonomic identifieri456442 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanomicrobiaMethanomicrobialesMethanoregulaceaeMethanoregula
Proteomesi
  • UP000002408 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 2602605'-nucleotidase SurEPRO_0000335298Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi456442.Mboo_0919.

Structurei

3D structure databases

ProteinModelPortaliA7I6S6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the SurE nucleotidase family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG02303. Archaea.
COG0496. LUCA.
HOGENOMiHOG000122501.
KOiK03787.
OMAiKICRQAK.

Family and domain databases

Gene3Di3.40.1210.10. 1 hit.
HAMAPiMF_00060. SurE.
InterProiIPR030048. SurE.
IPR002828. SurE-like_Pase/nucleotidase.
[Graphical view]
PfamiPF01975. SurE. 1 hit.
[Graphical view]
SUPFAMiSSF64167. SSF64167. 1 hit.
TIGRFAMsiTIGR00087. surE. 1 hit.

Sequencei

Sequence statusi: Complete.

A7I6S6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRPAILLTND DGVNSLGIWA AYEALSPIAD VTVVAPATQQ SAVGRSISIF
60 70 80 90 100
EPIRANRIKI NGNPAWAVGG KPTDAAIIGL YALKLAPALV VSGINIGENL
110 120 130 140 150
SYESIMTSGT VGAALEAANQ GTKGIAFSLQ VEDQGDKFDD PGQSAQSFDA
160 170 180 190 200
AKKVVRDVVE RVLASGFPPA ADVINVNIPS TIKGGYEVTH LARKLFHTGV
210 220 230 240 250
EKRLDPRGRP YFWINGPLLE DAEEGTDVHA VRKGNVSITP ITLDCTARTA
260
DEDTKKIFLK
Length:260
Mass (Da):27,591
Last modified:September 11, 2007 - v1
Checksum:iCE5636D349746047
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000780 Genomic DNA. Translation: ABS55437.1.
RefSeqiWP_012106462.1. NC_009712.1.

Genome annotation databases

EnsemblBacteriaiABS55437; ABS55437; Mboo_0919.
GeneIDi5410084.
KEGGimbn:Mboo_0919.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000780 Genomic DNA. Translation: ABS55437.1.
RefSeqiWP_012106462.1. NC_009712.1.

3D structure databases

ProteinModelPortaliA7I6S6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi456442.Mboo_0919.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABS55437; ABS55437; Mboo_0919.
GeneIDi5410084.
KEGGimbn:Mboo_0919.

Phylogenomic databases

eggNOGiarCOG02303. Archaea.
COG0496. LUCA.
HOGENOMiHOG000122501.
KOiK03787.
OMAiKICRQAK.

Enzyme and pathway databases

BioCyciMBOO456442:GH2T-939-MONOMER.

Family and domain databases

Gene3Di3.40.1210.10. 1 hit.
HAMAPiMF_00060. SurE.
InterProiIPR030048. SurE.
IPR002828. SurE-like_Pase/nucleotidase.
[Graphical view]
PfamiPF01975. SurE. 1 hit.
[Graphical view]
SUPFAMiSSF64167. SSF64167. 1 hit.
TIGRFAMsiTIGR00087. surE. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 6A8.

Entry informationi

Entry nameiSURE_METB6
AccessioniPrimary (citable) accession number: A7I6S6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: September 11, 2007
Last modified: December 9, 2015
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.