A7I6N9 (DCD_METB6) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable deoxycytidine triphosphate deaminase
Short name=dCTP deaminase
EC=3.5.4.13

Gene names

Name:	dcd
Ordered Locus Names:	Mboo_0882

Organism

Methanoregula boonei (strain 6A8) [Complete proteome] [HAMAP]

Taxonomic identifier

456442 [NCBI]

Taxonomic lineage

cellular organisms › Archaea › Euryarchaeota › Methanomicrobia › Methanomicrobiales › Methanoregulaceae › Methanoregula › Methanoregula boonei

Protein attributes

Sequence length	183 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	dCTP + H2O = dUTP + NH3. HAMAP-Rule MF_00146
Pathway	Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2. HAMAP-Rule MF_00146
Sequence similarities	Belongs to the dCTP deaminase family.

Ontologies

Keywords
Biological process	Nucleotide metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	dUMP biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway dUTP biosynthetic process Inferred from electronic annotation. Source: InterPro pyrimidine ribonucleotide biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular_function	dCTP deaminase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 183	183	Probable deoxycytidine triphosphate deaminase HAMAP-Rule MF_00146		PRO_1000117981

Sequences

	Sequence		Length	Mass (Da)
	A7I6N9 [UniParc]. Last modified September 11, 2007. Version 1. Checksum: 1E84A471EF7B86E0	FASTA	183	20,555
	10 20 30 40 50 60 MILVDWQLRD RIARGHIRID PFDPALVQPN SIDIRLGNHF VWYAPGKQVI DPYDKTTVTS 70 80 90 100 110 120 GVEGKHADFF DLLPGQFVLA ETLECISLPD NIVATIEGKS SIARLGVTLH QTGGWIDAGF 130 140 150 160 170 180 RGSITLEMAN VNARPVRVYA GMPIGQLVFY TTERAENPYD KKADAKYLDQ RQATLSKYHE NRK

References

[1]

"Complete sequence of Candidatus Methanoregula boonei 6A8." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Meincke L., Brettin T., Bruce D., Detter J.C., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M. , Hauser L., Kyrpides N., Kim E., Zinder S., Richardson P. Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 6A8.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000780 Genomic DNA. Translation: ABS55400.1.
RefSeq	YP_001404043.1. NC_009712.1.
3D structure databases
ProteinModelPortal	A7I6N9.
ModBase	Search...
Protein-protein interaction databases
STRING	456442.Mboo_0882.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABS55400; ABS55400; Mboo_0882.
GeneID	5410763.
KEGG	mbn:Mboo_0882.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0717.
HOGENOM	HOG000228601.
KO	K01494.
OMA	LELYNAN.
ProtClustDB	CLSK949569.
Enzyme and pathway databases
BioCyc	MBOO456442:GH2T-902-MONOMER.
UniPathway	UPA00610; UER00665.
Family and domain databases
HAMAP	MF_00146. dCTP_deaminase.
InterPro	IPR011962. dCTP_deam. IPR008180. dUTP_pyroPase. [Graphical view]
Pfam	PF00692. dUTPase. 1 hit. [Graphical view]
TIGRFAMs	TIGR02274. dCTP_deam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DCD_METB6

Accession

Primary (citable) accession number: A7I6N9

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	September 11, 2007
Last modified:	May 29, 2013
This is version 40 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program