A7I5W3 (A7I5W3_METB6) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Peptide methionine sulfoxide reductase MsrB HAMAP MF_01400
EC=1.8.4.12 HAMAP MF_01400

Alternative name(s):
Peptide-methionine (R)-S-oxide reductase HAMAP MF_01400

Gene names

Name:	msrB HAMAP MF_01400
Ordered Locus Names:	Mboo_0606

Organism

Methanoregula boonei (strain 6A8) [Complete proteome] [HAMAP]

Taxonomic identifier

456442 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanomicrobia › Methanomicrobiales › Genera incertae sedis › Methanoregula

Protein attributes

Sequence length	163 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (R)-S-oxide + thioredoxin. HAMAP MF_01400
Cofactor	Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein By similarity. HAMAP MF_01400
Sequence similarities	Belongs to the MsrB Met sulfoxide reductase family. HAMAP MF_01400

Ontologies

Keywords
Ligand	Metal-binding HAMAP MF_01400 Zinc HAMAP MF_01400
Molecular function	Oxidoreductase HAMAP MF_01400 EMBL ABS55124.1
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	peptide-methionine (R)-S-oxide reductase activity Inferred from electronic annotation. Source: EC peptide-methionine-(S)-S-oxide reductase activity Inferred from electronic annotation. Source: HAMAP zinc ion binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	146	1	Nucleophile By similarity HAMAP MF_01400
	Metal binding	74	1	Zinc By similarity HAMAP MF_01400
	Metal binding	77	1	Zinc By similarity HAMAP MF_01400
	Metal binding	123	1	Zinc By similarity HAMAP MF_01400
	Metal binding	126	1	Zinc By similarity HAMAP MF_01400

Sequences

	Sequence		Length	Mass (Da)
	A7I5W3 [UniParc]. Last modified September 11, 2007. Version 1. Checksum: 5AEABB0CD9604818	FASTA	163	17,733
	10 20 30 40 50 60 MIQNTPKTEG GAGVVPIFDP ETGRVEERTV IQKTDAEWQA QLTPEQFSVA RKQGTEYAFT 70 80 90 100 110 120 GKYHDCKAPG TYCCACCGTP LFSSDTKFDS GTGWPSFSAP VSPLNVRTHT DRSNGMVRTE 130 140 150 160 VLCARCRAHL GHVFDDGPKP TGKRYCMNSA ALDLHVAPGE KTC

References

[1]

"Complete sequence of Candidatus Methanoregula boonei 6A8." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Meincke L., Brettin T., Bruce D., Detter J.C., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M. , Hauser L., Kyrpides N., Kim E., Zinder S., Richardson P. Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 6A8.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000780 Genomic DNA. Translation: ABS55124.1.
RefSeq	YP_001403767.1. NC_009712.1.
3D structure databases
ProteinModelPortal	A7I5W3.
ModBase	Search...
Protein-protein interaction databases
STRING	A7I5W3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5412166.
GenomeReviews	Gene locus Mboo_0606 in contig CP000780_GR.
KEGG	mbn:Mboo_0606.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	arNOG10043.
HOGENOM	HBG715255.
OMA	KVTLHAD.
Family and domain databases
HAMAP	MF_01400. MsrB. [Tree]
InterPro	IPR002579. Methionine_sulphoxide_MsrB. IPR011057. Mss4-like. [Graphical view]
Gene3D	G3DSA:2.170.150.20. MsrB. 1 hit.
KO	K07305.
Pfam	PF01641. SelR. 1 hit. [Graphical view]
SUPFAM	SSF51316. Mss4_like. 1 hit.
TIGRFAMs	TIGR00357. TIGR00357. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A7I5W3_METB6

Accession

Primary (citable) accession number: A7I5W3

Entry history

Integrated into UniProtKB/TrEMBL:	September 11, 2007
Last sequence update:	September 11, 2007
Last modified:	December 14, 2011
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)