Skip Header

Contribute Send feedback
Read comments (?) or add your own

A7I5N5 (A7I5N5_METB6) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 30. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
5,10-methylenetetrahydromethanopterin reductase HAMAP MF_01091
EC=1.5.99.11 HAMAP MF_01091
Alternative name(s):
Coenzyme F420-dependent N(5),N(10)-methylenetetrahydromethanopterin reductase HAMAP MF_01091
Methylene-H(4)MPT reductase HAMAP MF_01091
Gene names
Name:mer HAMAP MF_01091
Ordered Locus Names:Mboo_0528
OrganismMethanoregula boonei (strain 6A8) [Complete proteome] [HAMAP]
Taxonomic identifier456442 [NCBI]
Taxonomic lineageArchaea › Euryarchaeota › Methanomicrobia › Methanomicrobiales › Genera incertae sedis › Methanoregula

Protein attributes

Sequence length328 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the reversible reduction of methylene-H4MPT to methyl-H4MPT By similarity. HAMAP MF_01091

Catalytic activity

5-methyltetrahydromethanopterin + coenzyme F420 = 5,10-methylenetetrahydromethanopterin + reduced coenzyme F420. HAMAP MF_01091

Pathway

One-carbon metabolism; methanogenesis from CO(2); methyl-coenzyme M from 5,10-methylene-5,6,7,8-tetrahydromethanopterin: step 1/2. HAMAP MF_01091

Subcellular location

Cytoplasm By similarity HAMAP MF_01091.

Sequence similarities

Belongs to the mer family. HAMAP MF_01091

Sequences

Sequence LengthMass (Da)Tools
A7I5N5 [UniParc].

Last modified September 11, 2007. Version 1.
Checksum: D95CF4CD7F21EF41

FASTA32834,792
        10         20         30         40         50         60 
MTYGIEFVPG NVNVKQVVNF CKLAESKDID FAWITNHYNN RHCYAVLAAV AQATTTLKMG 

        70         80         90        100        110        120 
PGIMNSFTDT PAAMASFMCT LNEISDGRAV LGIGPGDLST LPKIAIHPEK PVARLEEAVI 

       130        140        150        160        170        180 
QFRKLVAGEQ VNKSGLHFFD YDGAKLTGVT LPGKKGIPVY IGAQGPKVLE LAGKIGDGAL 

       190        200        210        220        230        240 
INASNPKDFQ VAIPIIQKAA EAVGKKGFDV GAYTAMSIDK SEKKARNAAK IVAAFIAAGS 

       250        260        270        280        290        300 
PPELLTRHGL DLNNVAKIKA ALGKFDFKTV GELVGDKEID AFTIAGTPEM VKAKCEDLTK 

       310        320 
AGVTQIIFGS PLGPDMTTSI RLLGKYIV

« Hide

References

[1]"Complete sequence of Candidatus Methanoregula boonei 6A8."
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Meincke L., Brettin T., Bruce D., Detter J.C., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Kyrpides N., Kim E., Zinder S., Richardson P.
Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 6A8.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000780 Genomic DNA. Translation: ABS55046.1.
RefSeqYP_001403689.1. NC_009712.1.

3D structure databases

ProteinModelPortalA7I5N5.
ModBaseSearch...

Protein-protein interaction databases

STRINGA7I5N5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5411755.
GenomeReviewsGene locus Mboo_0528 in contig CP000780_GR.
KEGGmbn:Mboo_0528.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGarNOG04928.
HOGENOMHBG497169.
OMAGIEFVPG.
ProtClustDBPRK02271.

Family and domain databases

HAMAPMF_01091. F420_mer.
[Tree]
InterProIPR011251. Luciferase-like_dom.
IPR019946. MeH4methanopterin_reductase.
[Graphical view]
Gene3DG3DSA:3.20.20.30. Luciferase_like. 1 hit.
KOK00320.
PfamPF00296. Bac_luciferase. 1 hit.
[Graphical view]
SUPFAMSSF51679. Luciferase_like. 1 hit.
TIGRFAMsTIGR03555. F420_mer. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA7I5N5_METB6
AccessionPrimary (citable) accession number: A7I5N5
Entry history
Integrated into UniProtKB/TrEMBL: September 11, 2007
Last sequence update: September 11, 2007
Last modified: December 14, 2011
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info