ID   A7I4R6_METB6            Unreviewed;       370 AA.
AC   A7I4R6;
DT   11-SEP-2007, integrated into UniProtKB/TrEMBL.
DT   11-SEP-2007, sequence version 1.
DT   27-MAR-2024, entry version 78.
DE   SubName: Full=Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein {ECO:0000313|EMBL:ABS54727.1};
GN   OrderedLocusNames=Mboo_0204 {ECO:0000313|EMBL:ABS54727.1};
OS   Methanoregula boonei (strain DSM 21154 / JCM 14090 / 6A8).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanomicrobiales; Methanoregulaceae; Methanoregula.
OX   NCBI_TaxID=456442 {ECO:0000313|EMBL:ABS54727.1, ECO:0000313|Proteomes:UP000002408};
RN   [1] {ECO:0000313|Proteomes:UP000002408}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 21154 / JCM 14090 / 6A8
RC   {ECO:0000313|Proteomes:UP000002408};
RX   PubMed=25998264; DOI=10.1099/mic.0.000117;
RA   Braeuer S., Cadillo-Quiroz H., Kyrpides N., Woyke T., Goodwin L.,
RA   Detter C., Podell S., Yavitt J.B., Zinder S.H.;
RT   "Genome of Methanoregula boonei 6A8 reveals adaptations to oligotrophic
RT   peatland environments.";
RL   Microbiology 161:1572-1581(2015).
CC   -!- SUBUNIT: Heterotetramer of one alpha, one beta, one delta and one gamma
CC       chain. {ECO:0000256|ARBA:ARBA00011595}.
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DR   EMBL; CP000780; ABS54727.1; -; Genomic_DNA.
DR   RefSeq; WP_011991215.1; NC_009712.1.
DR   AlphaFoldDB; A7I4R6; -.
DR   STRING; 456442.Mboo_0204; -.
DR   GeneID; 5411151; -.
DR   KEGG; mbn:Mboo_0204; -.
DR   eggNOG; arCOG01608; Archaea.
DR   HOGENOM; CLU_002569_5_0_2; -.
DR   OrthoDB; 372068at2157; -.
DR   Proteomes; UP000002408; Chromosome.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0006082; P:organic acid metabolic process; IEA:UniProt.
DR   GO; GO:1901576; P:organic substance biosynthetic process; IEA:UniProt.
DR   GO; GO:0044272; P:sulfur compound biosynthetic process; IEA:UniProt.
DR   CDD; cd07034; TPP_PYR_PFOR_IOR-alpha_like; 1.
DR   Gene3D; 3.40.50.920; -; 1.
DR   Gene3D; 3.40.50.970; -; 1.
DR   InterPro; IPR033412; PFOR_II.
DR   InterPro; IPR002880; Pyrv_Fd/Flavodoxin_OxRdtase_N.
DR   InterPro; IPR029061; THDP-binding.
DR   InterPro; IPR009014; Transketo_C/PFOR_II.
DR   PANTHER; PTHR32154; PYRUVATE-FLAVODOXIN OXIDOREDUCTASE-RELATED; 1.
DR   PANTHER; PTHR32154:SF0; PYRUVATE-FLAVODOXIN OXIDOREDUCTASE-RELATED; 1.
DR   Pfam; PF17147; PFOR_II; 1.
DR   Pfam; PF01855; POR_N; 1.
DR   SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
DR   SUPFAM; SSF52922; TK C-terminal domain-like; 1.
PE   4: Predicted;
KW   Pyruvate {ECO:0000313|EMBL:ABS54727.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002408}.
FT   DOMAIN          14..232
FT                   /note="Pyruvate flavodoxin/ferredoxin oxidoreductase
FT                   pyrimidine binding"
FT                   /evidence="ECO:0000259|Pfam:PF01855"
FT   DOMAIN          256..349
FT                   /note="Pyruvate:ferredoxin oxidoreductase core"
FT                   /evidence="ECO:0000259|Pfam:PF17147"
SQ   SEQUENCE   370 AA;  40951 MW;  E5AF7D32E2680746 CRC64;
     MKKIATGNKA IAEAVKQALP GVVAAYPITP QTEIVETIAD FVTSGQMKSR YIPVESEHSA
     MAACIGASIT GTRTFTATSA HGLLYMHEMT NWAAGARLPI VMANVNRSLG PGWNIWAEHT
     DAMQERDTGW LQVYVSTVQE AYDTTLMAFR IAEHNDVLLP VMVNLDGFSL SHIMQPLDTV
     EPGDFIPPLH LPHAIDTKNP TGYGGLTGPD QHFRFRWDIE RSIRDSVNVI EETELDFAAR
     FGRRYGPVEE YRCEDADVVL LAMGTLGKEA EVAIDILRKE GIKAGSLRLR WFRPFPKLDL
     AGKEVVVIDR DYSFGYGGIV ANEILAKNKC DVYNVIAGLG GQEVTYDDMA GFVRERRIGE
     ESWFGVNSHV
//