A7I3X1 (RSMG_CAMHC) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribosomal RNA small subunit methyltransferase G
EC=2.1.1.170

Alternative name(s):
16S rRNA 7-methylguanosine methyltransferase
Short name=16S rRNA m7G methyltransferase

Gene names

Name:	rsmG
Ordered Locus Names:	CHAB381_1700

Organism

Campylobacter hominis (strain ATCC BAA-381 / LMG 19568 / NCTC 13146 / CH001A) [Complete proteome] [HAMAP]

Taxonomic identifier

360107 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › delta/epsilon subdivisions › Epsilonproteobacteria › Campylobacterales › Campylobacteraceae › Campylobacter › Campylobacter hominis

Protein attributes

Sequence length	183 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Specifically methylates the N7 position of guanine in position 527 of 16S rRNA By similarity. HAMAP-Rule MF_00074
Catalytic activity	S-adenosyl-L-methionine + guanine(527) in 16S rRNA = S-adenosyl-L-homocysteine + N(7)-methylguanine(527) in 16S rRNA. HAMAP-Rule MF_00074
Subcellular location	Cytoplasm Potential HAMAP-Rule MF_00074.
Sequence similarities	Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.

Ontologies

Keywords
Biological process	rRNA processing
Cellular component	Cytoplasm
Ligand	S-adenosyl-L-methionine
Molecular function	Methyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	rRNA (guanine-N7)-methylation Inferred from electronic annotation. Source: GOC
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	rRNA (guanine-N7-)-methyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 183	183	Ribosomal RNA small subunit methyltransferase G HAMAP-Rule MF_00074		PRO_0000342909
Regions
	Region	111 – 112	2	S-adenosyl-L-methionine binding By similarity
Sites
	Binding site	60	1	S-adenosyl-L-methionine; via carbonyl oxygen By similarity
	Binding site	65	1	S-adenosyl-L-methionine; via carbonyl oxygen By similarity
	Binding site	125	1	S-adenosyl-L-methionine By similarity

Sequences

	Sequence		Length	Mass (Da)
	A7I3X1 [UniParc]. Last modified September 11, 2007. Version 1. Checksum: DA93D8E64AAD499A	FASTA	183	20,861
	10 20 30 40 50 60 MIIKKPENFN EQIEQFGKCL EKFNKIHSIT NYNDLSAVIE DSLEGLKFIT EMPKVAIDIG 70 80 90 100 110 120 SGAGFPAIFL AMVLPYTKWH LFEPNTKKAA FLTYAKVNLK LKNIIIHNTK IENETPFIAD 130 140 150 160 170 180 LITSRAVMKV PDLIKISHGF FDTHTKFLFY KGSNVKDELG NLKAEIFENN MRKYALLKGN DVC

References

[1]

"Complete genome sequence of Campylobacter hominis ATCC BAA-381, a commensal isolated from the human gastrointestinal tract." Fouts D.E., Mongodin E.F., Puiu D., Sebastian Y., Miller W.G., Mandrell R.E., Nelson K.E. Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-381 / LMG 19568 / NCTC 13146 / CH001A.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000776 Genomic DNA. Translation: ABS51378.1.
RefSeq	YP_001407212.1. NC_009714.1.
3D structure databases
ProteinModelPortal	A7I3X1.
ModBase	Search...
Protein-protein interaction databases
STRING	360107.CHAB381_1700.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABS51378; ABS51378; CHAB381_1700.
GeneID	5409482.
KEGG	cha:CHAB381_1700.
PATRIC	20041506. VBICamHom81367_1619.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0357.
HOGENOM	HOG000221012.
KO	K03501.
OMA	GFYDENT.
ProtClustDB	CLSK961505.
Enzyme and pathway databases
BioCyc	CHOM360107:GHCX-1705-MONOMER.
Family and domain databases
HAMAP	MF_00074. 16SrRNA_methyltr_G.
InterPro	IPR003682. rRNA_ssu_MeTfrase_G. [Graphical view]
Pfam	PF02527. GidB. 1 hit. [Graphical view]
TIGRFAMs	TIGR00138. gidB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RSMG_CAMHC

Accession

Primary (citable) accession number: A7I3X1

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 1, 2008
Last sequence update:	September 11, 2007
Last modified:	May 1, 2013
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program