A7I3J2 (DCD_CAMHC) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Deoxycytidine triphosphate deaminase
Short name=dCTP deaminase
EC=3.5.4.13

Gene names

Name:	dcd
Ordered Locus Names:	CHAB381_1552

Organism

Campylobacter hominis (strain ATCC BAA-381 / LMG 19568 / NCTC 13146 / CH001A) [Complete proteome] [HAMAP]

Taxonomic identifier

360107 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Epsilonproteobacteria › Campylobacterales › Campylobacteraceae › Campylobacter

Protein attributes

Sequence length	190 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	dCTP + H2O = dUTP + NH3. HAMAP MF_00146
Pathway	Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2. HAMAP MF_00146
Sequence similarities	Belongs to the dCTP deaminase family.

Ontologies

Keywords
Biological process	Nucleotide metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	dUTP biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	dCTP deaminase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 190	190	Deoxycytidine triphosphate deaminase HAMAP MF_00146		PRO_1000009701

Sequences

	Sequence		Length	Mass (Da)
	A7I3J2 [UniParc]. Last modified September 11, 2007. Version 1. Checksum: E0655208BF263A0F	FASTA	190	21,116
	10 20 30 40 50 60 MGLKSDKWIR EQSIKNGMIT PFCEENMGVG VVSYGLSSYG YDIRVADEFK IFTNVGGTVV 70 80 90 100 110 120 DPKNFDEKNI VDFKGDVCIV PPNSFALART IEYFKMPRDV LAICLGKSTY ARCGIIVNVT 130 140 150 160 170 180 PFEPGFEGHI TIEISNTTPL PAKIYANEGI AQVLFLQGDE ICEVSYADKK GKYQRQKGIT 190 LPRILEGDKK

References

[1]

"Complete genome sequence of Campylobacter hominis ATCC BAA-381, a commensal isolated from the human gastrointestinal tract." Fouts D.E., Mongodin E.F., Puiu D., Sebastian Y., Miller W.G., Mandrell R.E., Nelson K.E. Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-381 / LMG 19568 / NCTC 13146 / CH001A.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000776 Genomic DNA. Translation: ABS51590.1.
RefSeq	YP_001407083.1. NC_009714.1.
3D structure databases
ProteinModelPortal	A7I3J2.
ModBase	Search...
Protein-protein interaction databases
STRING	A7I3J2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5408501.
GenomeReviews	Gene locus CHAB381_1552 in contig CP000776_GR.
KEGG	cha:CHAB381_1552.
NMPDR	fig|360107.5.peg.1512.
PATRIC	20041208. VBICamHom81367_1487.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0717.
HOGENOM	HBG553199.
OMA	MEYFRIP.
ProtClustDB	PRK00416.
Enzyme and pathway databases
BioCyc	CHOM360107:CHAB381_1552-MONOMER.
Family and domain databases
HAMAP	MF_00146. dCTP_deaminase. [Tree]
InterPro	IPR011962. dCTP_deam. IPR008180. dUTP_pyroPase. [Graphical view]
KO	K01494.
Pfam	PF00692. dUTPase. 1 hit. [Graphical view]
TIGRFAMs	TIGR02274. DCTP_deam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DCD_CAMHC

Accession

Primary (citable) accession number: A7I3J2

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	September 11, 2007
Last modified:	January 25, 2012
This is version 28 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program