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A7I2H6 (ACKA_CAMHC) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 31. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Acetate kinase
EC=2.7.2.1
Alternative name(s):
Acetokinase
Gene names
Name:ackA
Ordered Locus Names:CHAB381_1162
OrganismCampylobacter hominis (strain ATCC BAA-381 / LMG 19568 / NCTC 13146 / CH001A) [Complete proteome] [HAMAP]
Taxonomic identifier360107 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Epsilonproteobacteria › Campylobacterales › Campylobacteraceae › Campylobacter

Protein attributes

Sequence length399 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + acetate = ADP + acetyl phosphate. HAMAP MF_00020

ATP + propanoate = ADP + propanoyl phosphate. HAMAP MF_00020

Pathway

Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. HAMAP MF_00020

Subcellular location

Cytoplasm By similarity HAMAP MF_00020.

Sequence similarities

Belongs to the acetokinase family.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processorganic acid metabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

acetate kinase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 399399Acetate kinase HAMAP MF_00020
PRO_1000089964

Sequences

Sequence LengthMass (Da)Tools
A7I2H6 [UniParc].

Last modified September 11, 2007. Version 1.
Checksum: ECC499254EAFED1E

FASTA39944,298
        10         20         30         40         50         60 
MKILVINSGS SSIKFKFYDL KIQKCLASGM IEQIGDEVSH SKIETCDGKT IEENMEIRTH 

        70         80         90        100        110        120 
DEGIVILNRY LKETGVLTDL KEIDGVGHRI VQGADYFEGP ALVDDDVITK IEELIPLAPL 

       130        140        150        160        170        180 
HNPAHLSGIR SSLRHAPCLP NVVVFDNTFY HNIPDYAYMY ALPYKFYEKY RVRKFGAHGI 

       190        200        210        220        230        240 
SHEFVTKKGA DFLGIDYKNF CVISLHIGSG SSISATKDGI CIDTSMGLTP LEGLMMSTRC 

       250        260        270        280        290        300 
GSVDPAIIPY MKRVAGYLSE DIDTIMNKKS GLLGITGTSD FRKVLERMHK GDERAKLAFD 

       310        320        330        340        350        360 
MLTYQIVKII GSYYAILPRV DAIIWTAGIG ENSAELRESV SKRLAHFGVG VDETVNVNCI 

       370        380        390 
KKPTDISSQN ATIKTLVIPT DEEYSIAKAT ERILLSLKK

« Hide

References

[1]"Complete genome sequence of Campylobacter hominis ATCC BAA-381, a commensal isolated from the human gastrointestinal tract."
Fouts D.E., Mongodin E.F., Puiu D., Sebastian Y., Miller W.G., Mandrell R.E., Nelson K.E.
Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-381 / LMG 19568 / NCTC 13146 / CH001A.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000776 Genomic DNA. Translation: ABS51966.1.
RefSeqYP_001406717.1. NC_009714.1.

3D structure databases

ProteinModelPortalA7I2H6.
ModBaseSearch...

Protein-protein interaction databases

STRINGA7I2H6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5408305.
GenomeReviewsGene locus CHAB381_1162 in contig CP000776_GR.
KEGGcha:CHAB381_1162.
NMPDRfig|360107.5.peg.1141.
PATRIC20040442. VBICamHom81367_1116.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0282.
HOGENOMHBG285863.
OMANPVEADY.
ProtClustDBPRK00180.

Enzyme and pathway databases

BioCycCHOM360107:CHAB381_1162-MONOMER.

Family and domain databases

HAMAPMF_00020. Acetate_kinase.
[Tree]
InterProIPR004372. Ac/Proprionate_kinase.
IPR000890. Aliphatic_acid_kin_short-chain.
IPR023865. Aliphatic_acid_kinase_CS.
[Graphical view]
KOK00925.
PANTHERPTHR21060. Acetate_kin. 1 hit.
PfamPF00871. Acetate_kinase. 1 hit.
[Graphical view]
PIRSFPIRSF000722. Acetate_prop_kin. 1 hit.
PRINTSPR00471. ACETATEKNASE.
TIGRFAMsTIGR00016. AckA. 1 hit.
PROSITEPS01075. ACETATE_KINASE_1. 1 hit.
PS01076. ACETATE_KINASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameACKA_CAMHC
AccessionPrimary (citable) accession number: A7I2H6
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: September 11, 2007
Last modified: January 25, 2012
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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