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A7I208 (A7I208_CAMHC) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 34. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ferrochelatase HAMAP MF_00323 RuleBase RU000607
EC=4.99.1.1 HAMAP MF_00323 RuleBase RU000607
Alternative name(s):
Heme synthase HAMAP MF_00323
Protoheme ferro-lyase HAMAP MF_00323
Gene names
Name:hemH HAMAP MF_00323 EMBL ABS51530.1
Ordered Locus Names:CHAB381_0988
OrganismCampylobacter hominis (strain ATCC BAA-381 / LMG 19568 / NCTC 13146 / CH001A) [Complete proteome] [HAMAP]
Taxonomic identifier360107 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Epsilonproteobacteria › Campylobacterales › Campylobacteraceae › Campylobacter

Protein attributes

Sequence length312 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the ferrous insertion into protoporphyrin IX By similarity. HAMAP MF_00323 RuleBase RU000607 SAAS SAAS001015

Catalytic activity

Protoheme + 2 H+ = protoporphyrin + Fe2+. HAMAP MF_00323 RuleBase RU000607 SAAS SAAS001015

Pathway

Porphyrin metabolism; protoheme biosynthesis; protoheme from protoporphyrin-IX: step 1/1. HAMAP MF_00323 RuleBase RU000607 SAAS SAAS001015

Subcellular location

Cytoplasm By similarity HAMAP MF_00323.

Sequence similarities

Belongs to the ferrochelatase family. HAMAP MF_00323 RuleBase RU004185

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding1861Iron By similarity HAMAP MF_00323
Metal binding2671Iron By similarity HAMAP MF_00323

Sequences

Sequence LengthMass (Da)Tools
A7I208 [UniParc].

Last modified September 11, 2007. Version 1.
Checksum: 6123F2F297CFBAB2

FASTA31235,925
        10         20         30         40         50         60 
MLKKAVLLLN MGGPGKLEEV EIFLKNMFND PFILSIKSSF CRKILAFIIT FFRKKKAEEN 

        70         80         90        100        110        120 
YLQIGGTSPI NALTISLVNK MKALAPNYVC VDFAMNYTKP FANEVLKKYE NFDDIILIPL 

       130        140        150        160        170        180 
YPHYSQTTVK SSIQSCKKAM SKDFKICEVF YKNEKYNEIL LNLIKDEISN FSAEEISEIS 

       190        200        210        220        230        240 
LIFSAHSLPI KIIEKGDPYE KQIREHVEIL SEMLKQKGVN FKEIILAYQS RLGPVKWLGP 

       250        260        270        280        290        300 
NTGDVLKNLK NKKALIFPLA FCIDNSETVF ELAVQYAKIA RERNFTFYKV CKCPNDRDEF 

       310 
AEFLLDLAKN EK

« Hide

References

[1]"Complete genome sequence of Campylobacter hominis ATCC BAA-381, a commensal isolated from the human gastrointestinal tract."
Fouts D.E., Mongodin E.F., Puiu D., Sebastian Y., Miller W.G., Mandrell R.E., Nelson K.E.
Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000776 Genomic DNA. Translation: ABS51530.1.
RefSeqYP_001406549.1. NC_009714.1.

3D structure databases

ProteinModelPortalA7I208.
ModBaseSearch...

Protein-protein interaction databases

STRINGA7I208.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5409705.
GenomeReviewsGene locus CHAB381_0988 in contig CP000776_GR.
KEGGcha:CHAB381_0988.
NMPDRfig|360107.5.peg.970.
PATRIC20040106. VBICamHom81367_0948.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0276.
HOGENOMHBG697135.
OMAKPWLGGQ.
ProtClustDBPRK00035.

Family and domain databases

HAMAPMF_00323. Ferrochelatase.
[Tree]
InterProIPR001015. Ferrochelatase.
IPR019772. Ferrochelatase_AS.
[Graphical view]
KOK01772.
PANTHERPTHR11108. Ferrochelatase. 1 hit.
PfamPF00762. Ferrochelatase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00109. HemH. 1 hit.
PROSITEPS00534. FERROCHELATASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA7I208_CAMHC
AccessionPrimary (citable) accession number: A7I208
Entry history
Integrated into UniProtKB/TrEMBL: September 11, 2007
Last sequence update: September 11, 2007
Last modified: December 14, 2011
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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