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A7I1G1 (PGK_CAMHC) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 45. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphoglycerate kinase

EC=2.7.2.3
Gene names
Name:pgk
Ordered Locus Names:CHAB381_0778
OrganismCampylobacter hominis (strain ATCC BAA-381 / LMG 19568 / NCTC 13146 / CH001A) [Complete proteome] [HAMAP]
Taxonomic identifier360107 [NCBI]
Taxonomic lineageBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesCampylobacteraceaeCampylobacter

Protein attributes

Sequence length405 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate. HAMAP-Rule MF_00145

Pathway

Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5. HAMAP-Rule MF_00145

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00145

Subcellular location

Cytoplasm Potential HAMAP-Rule MF_00145.

Sequence similarities

Belongs to the phosphoglycerate kinase family.

Ontologies

Keywords
   Biological processGlycolysis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglycolytic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

phosphoglycerate kinase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 405405Phosphoglycerate kinase HAMAP-Rule MF_00145
PRO_1000203324

Regions

Nucleotide binding355 – 3584ATP By similarity
Region23 – 253Substrate binding By similarity
Region62 – 654Substrate binding By similarity

Sites

Binding site391Substrate By similarity
Binding site1211Substrate By similarity
Binding site1541Substrate By similarity
Binding site2071ATP By similarity
Binding site2981ATP; via carbonyl oxygen By similarity
Binding site3291ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
A7I1G1 [UniParc].

Last modified September 11, 2007. Version 1.
Checksum: 087CB9662E45F31F

FASTA40544,497
        10         20         30         40         50         60 
MGEILSVKDI KFKKGEKVFI RCDFNVPMDE FLNITDDRRI RAAIPTIRYC LDEGCSVILA 

        70         80         90        100        110        120 
SHLGRPKNGY EAKFSLEPVA KRLARRMNRE IKFVNDVIGK EAVEAVKNLK ENEVLLLDNL 

       130        140        150        160        170        180 
RFEKGETKND PEFAQKLASY ANYYINDAFG VCHRAHASVE AITKFYDNKH KAAGFLLIKE 

       190        200        210        220        230        240 
VNFAANLTKR PVRPFVAVAG GSKVSGKLQA LKNLLPKVDK LIIGGGMAFT FLKAIGYEIG 

       250        260        270        280        290        300 
NSLLEEDLVE EALNILREGK RLGVKIYIPV DAIVAPAISQ DSVMKNVTVQ EIPAGWMGLD 

       310        320        330        340        350        360 
IGPATIALFR EALSDAQTIW WNGPMGVFEI DKFARGSLRM SHAIAESNAT TVVGGGDTAD 

       370        380        390        400 
VVERAGNSDE MTFISTGGGA SLELIEGKEL PGVRVLTIKN DEMEC 

« Hide

References

[1]"Complete genome sequence of Campylobacter hominis ATCC BAA-381, a commensal isolated from the human gastrointestinal tract."
Fouts D.E., Mongodin E.F., Puiu D., Sebastian Y., Miller W.G., Mandrell R.E., Nelson K.E.
Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-381 / LMG 19568 / NCTC 13146 / CH001A.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000776 Genomic DNA. Translation: ABS51963.1.
RefSeqYP_001406352.1. NC_009714.1.

3D structure databases

ProteinModelPortalA7I1G1.
SMRA7I1G1. Positions 4-399.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING360107.CHAB381_0778.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABS51963; ABS51963; CHAB381_0778.
GeneID5408262.
KEGGcha:CHAB381_0778.
PATRIC20039702. VBICamHom81367_0750.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0126.
HOGENOMHOG000227107.
KOK00927.
OMAAGHPVGK.
OrthoDBEOG64N9Z0.

Enzyme and pathway databases

BioCycCHOM360107:GHCX-783-MONOMER.
UniPathwayUPA00109; UER00185.

Family and domain databases

Gene3D3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPMF_00145. Phosphoglyc_kinase.
InterProIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERPTHR11406. PTHR11406. 1 hit.
PfamPF00162. PGK. 1 hit.
[Graphical view]
PIRSFPIRSF000724. Pgk. 1 hit.
PRINTSPR00477. PHGLYCKINASE.
SUPFAMSSF53748. SSF53748. 1 hit.
PROSITEPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePGK_CAMHC
AccessionPrimary (citable) accession number: A7I1G1
Entry history
Integrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: September 11, 2007
Last modified: June 11, 2014
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways