A7I198 (SYGA_CAMHC) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Glycine--tRNA ligase alpha subunit
EC=6.1.1.14

Alternative name(s):
Glycyl-tRNA synthetase alpha subunit
Short name=GlyRS

Gene names

Name:	glyQ
Ordered Locus Names:	CHAB381_0708

Organism

Campylobacter hominis (strain ATCC BAA-381 / LMG 19568 / NCTC 13146 / CH001A) [Complete proteome] [HAMAP]

Taxonomic identifier

360107 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Epsilonproteobacteria › Campylobacterales › Campylobacteraceae › Campylobacter

Protein attributes

Sequence length	301 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly). HAMAP MF_00254
Subunit structure	Tetramer of two alpha and two beta subunits By similarity.
Subcellular location	Cytoplasm HAMAP MF_00254.
Sequence similarities	Belongs to the class-II aminoacyl-tRNA synthetase family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycyl-tRNA aminoacylation Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW glycine-tRNA ligase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 301	301	Glycine--tRNA ligase alpha subunit HAMAP MF_00254		PRO_1000047407

Sequences

	Sequence		Length	Mass (Da)
	A7I198 [UniParc]. Last modified September 11, 2007. Version 1. Checksum: D49FEFF34C23E587	FASTA	301	34,619
	10 20 30 40 50 60 MTFSQIILTL QKYWNEQGCI IVQPYDMPAG AGTYHWATFL RSLGKKPWKA AYVAPSRRPT 70 80 90 100 110 120 DGRYGENPNR LGAYYQFQVI LKPSPDNIQE LYLKSLEILG LDIKNHDIRF VEDNWESPTL 130 140 150 160 170 180 GAWGLGWEVW LDGMEITQFT YFQQVGGIPC ELISGEITYG LERLAMYLQD IDNVYDIVWD 190 200 210 220 230 240 DNGGHKVLYG DVHKQSEFEF SKYNFELADT KMLFTQFDNC FKECKRILEQ KYIKDGVELD 250 260 270 280 290 300 GLALPAYDYC MLAAHTFNVL DARGAISVTQ RQDYILKIRE LAKGCALAYS KNSAQISSKK R

References

[1]

"Complete genome sequence of Campylobacter hominis ATCC BAA-381, a commensal isolated from the human gastrointestinal tract." Fouts D.E., Mongodin E.F., Puiu D., Sebastian Y., Miller W.G., Mandrell R.E., Nelson K.E. Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-381 / LMG 19568 / NCTC 13146 / CH001A.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000776 Genomic DNA. Translation: ABS51313.1.
RefSeq	YP_001406289.1. NC_009714.1.
3D structure databases
ProteinModelPortal	A7I198.
SMR	A7I198. Positions 1-289.
ModBase	Search...
Protein-protein interaction databases
STRING	A7I198.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5409403.
GenomeReviews	Gene locus CHAB381_0708 in contig CP000776_GR.
KEGG	cha:CHAB381_0708.
NMPDR	fig|360107.5.peg.698.
PATRIC	20039566. VBICamHom81367_0684.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0752.
HOGENOM	HBG285316.
OMA	CRRPTDG.
ProtClustDB	PRK09348.
Enzyme and pathway databases
BioCyc	CHOM360107:CHAB381_0708-MONOMER.
Family and domain databases
HAMAP	MF_00254. Gly_tRNA_synth_alpha. [Tree]
InterPro	IPR006194. Gly-tRNA-synth_II_heterodimer. IPR002310. Gly-tRNA_synth_IIc_asu. [Graphical view]
KO	K01878.
Pfam	PF02091. tRNA-synt_2e. 1 hit. [Graphical view]
PRINTS	PR01044. TRNASYNTHGA.
TIGRFAMs	TIGR00388. GlyQ. 1 hit.
PROSITE	PS50861. AA_TRNA_LIGASE_II_GLYAB. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SYGA_CAMHC

Accession

Primary (citable) accession number: A7I198

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	September 11, 2007
Last modified:	January 25, 2012
This is version 28 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program