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A7HZ54 (A7HZ54_PARL1) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 44. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Glutathione synthetase HAMAP-Rule MF_00162
EC=6.3.2.3 HAMAP-Rule MF_00162
Alternative name(s):
GSH synthetase HAMAP-Rule MF_00162
Glutathione synthase HAMAP-Rule MF_00162
Gene names
Name:gshB HAMAP-Rule MF_00162
Ordered Locus Names:Plav_3589
OrganismParvibaculum lavamentivorans (strain DS-1 / DSM 13023 / NCIMB 13966) [Complete proteome] [HAMAP] EMBL ABS65187.1
Taxonomic identifier402881 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Phyllobacteriaceae › Parvibaculum ›

Protein attributes

Sequence length312 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione. HAMAP-Rule MF_00162

Cofactor

Binds (magnesium or manganese,ion) per subunit By similarity. HAMAP-Rule MF_00162

Pathway

Sulfur metabolism; glutathione biosynthesis; glutathione from L-cysteine and L-glutamate: step 2/2. HAMAP-Rule MF_00162

Sequence similarities

Belongs to the prokaryotic GSH synthase family. HAMAP-Rule MF_00162

Contains 1 ATP-grasp domain. HAMAP-Rule MF_00162

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain125 – 309185ATP-grasp By similarity HAMAP-Rule MF_00162
Nucleotide binding151 – 20757ATP By similarity HAMAP-Rule MF_00162

Sites

Metal binding2801Magnesium or manganese By similarity HAMAP-Rule MF_00162
Metal binding2821Magnesium or manganese By similarity HAMAP-Rule MF_00162

Sequences

Sequence LengthMass (Da)Tools
A7HZ54 [UniParc].

Last modified September 11, 2007. Version 1.
Checksum: 2C2516CE9C63C899

FASTA31235,061
        10         20         30         40         50         60 
MSLSVAIQMD PIHSININAD STFALGLEAQ SRGHTLFYYE PKDLSMRDGR VYARMRPLTL 

        70         80         90        100        110        120 
RREVGNHSSL GSLEKIFLED VDVVLMRQDP PFDMSYITAT HLLETVHPKT LVVNDPAEVR 

       130        140        150        160        170        180 
NAPEKLFAVR FKGLLPPTLI SRDPEEIRAF RREFSDIIVK PLFGNGGVGV FRIRDGDENL 

       190        200        210        220        230        240 
NSLLEMFGQM NREPVIVQKY LPEVRQGDKR IILVDGKPVG AINRVPAEGE ARSNMHVGGR 

       250        260        270        280        290        300 
PEKWSLTKRE EEICETIGPE LKARGLIFVG IDVIGDYLTE INVTSPTGIQ EIDRFDSANL 

       310 
AGLVWDAIEA RR

« Hide

References

[1]"Complete genome sequence and annotation of Parvibaculum lavamentivorans DS-1."
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Saunders E., Brettin T., Bruce D., Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Richardson P.
Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DS-1 / DSM 13023 / NCIMB 13966.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000774 Genomic DNA. Translation: ABS65187.1.
RefSeqYP_001414844.1. NC_009719.1.

3D structure databases

ProteinModelPortalA7HZ54.
ModBaseSearch...

Protein-protein interaction databases

STRING402881.Plav_3589.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABS65187; ABS65187; Plav_3589.
GeneID5455146.
KEGGpla:Plav_3589.
PATRIC22868981. VBIParLav90819_3694.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0189.
HOGENOMHOG000265022.
KOK01920.
OMAWMRKDPP.
ProtClustDBPRK05246.

Enzyme and pathway databases

BioCycPLAV402881:GHQA-3635-MONOMER.
UniPathwayUPA00142; UER00210.

Family and domain databases

Gene3D3.30.1490.20. 1 hit.
3.30.470.20. 1 hit.
3.40.50.20. 1 hit.
HAMAPMF_00162. GSH_S.
InterProIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR006284. Glut_synth_pro.
IPR004218. GSHS_ATP-bd.
IPR004215. GSHS_N.
IPR016185. PreATP-grasp_dom.
[Graphical view]
PfamPF02955. GSH-S_ATP. 1 hit.
PF02951. GSH-S_N. 1 hit.
[Graphical view]
SUPFAMSSF52440. PreATP-grasp-like. 1 hit.
TIGRFAMsTIGR01380. glut_syn. 1 hit.
PROSITEPS50975. ATP_GRASP. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA7HZ54_PARL1
AccessionPrimary (citable) accession number: A7HZ54
Entry history
Integrated into UniProtKB/TrEMBL: September 11, 2007
Last sequence update: September 11, 2007
Last modified: May 1, 2013
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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