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Protein

Ribonuclease PH

Gene

rph

Organism
Parvibaculum lavamentivorans (strain DS-1 / DSM 13023 / NCIMB 13966)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates.UniRule annotation

Catalytic activityi

tRNA(n+1) + phosphate = tRNA(n) + a nucleoside diphosphate.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, Transferase

Keywords - Biological processi

tRNA processing

Enzyme and pathway databases

BioCyciPLAV402881:GHQA-3626-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonuclease PHUniRule annotation (EC:2.7.7.56UniRule annotation)
Short name:
RNase PHUniRule annotation
Alternative name(s):
tRNA nucleotidyltransferaseUniRule annotation
Gene namesi
Name:rphUniRule annotation
Ordered Locus Names:Plav_3580
OrganismiParvibaculum lavamentivorans (strain DS-1 / DSM 13023 / NCIMB 13966)
Taxonomic identifieri402881 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhodobiaceaeParvibaculum
Proteomesi
  • UP000006377 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 238238Ribonuclease PHPRO_1000072566Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi402881.Plav_3580.

Structurei

3D structure databases

ProteinModelPortaliA7HZ45.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RNase PH family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105ED0. Bacteria.
COG0689. LUCA.
HOGENOMiHOG000229516.
KOiK00989.
OMAiKGKGQGW.
OrthoDBiPOG091H03ML.

Family and domain databases

CDDicd11362. RNase_PH_bact. 1 hit.
Gene3Di3.30.230.70. 1 hit.
HAMAPiMF_00564. RNase_PH. 1 hit.
InterProiIPR001247. ExoRNase_PH_dom1.
IPR015847. ExoRNase_PH_dom2.
IPR027408. PNPase/RNase_PH_dom.
IPR020568. Ribosomal_S5_D2-typ_fold.
IPR002381. RNase_PH_bac-type.
IPR018336. RNase_PH_CS.
[Graphical view]
PfamiPF01138. RNase_PH. 1 hit.
PF03725. RNase_PH_C. 1 hit.
[Graphical view]
SUPFAMiSSF54211. SSF54211. 1 hit.
SSF55666. SSF55666. 1 hit.
TIGRFAMsiTIGR01966. RNasePH. 1 hit.
PROSITEiPS01277. RIBONUCLEASE_PH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A7HZ45-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRPSGRQPQE MRTVSFEPGV AKHAEGSCLV RFGDTHVLCT ASLEERVPPF
60 70 80 90 100
LKGGGQGWVT AEYGMLPRST HERMRREAAQ GKQSGRTQEI QRLVGRSLRS
110 120 130 140 150
VVDLKALGER QISVDCDVLQ ADGGTRTASI TGAWVALHQC IEWMRARSMI
160 170 180 190 200
SAPVLKDHVA AISCGIYQGV PVVDLDYAED STADTDANFV ITGKGGICEI
210 220 230
QGTAEGEPFS DEEFLSLLAL AKTSIADLVR RQKEAVSA
Length:238
Mass (Da):25,773
Last modified:September 11, 2007 - v1
Checksum:i9216B6AD4D576704
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000774 Genomic DNA. Translation: ABS65178.1.
RefSeqiWP_012112438.1. NC_009719.1.

Genome annotation databases

EnsemblBacteriaiABS65178; ABS65178; Plav_3580.
KEGGipla:Plav_3580.
PATRICi22868963. VBIParLav90819_3685.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000774 Genomic DNA. Translation: ABS65178.1.
RefSeqiWP_012112438.1. NC_009719.1.

3D structure databases

ProteinModelPortaliA7HZ45.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi402881.Plav_3580.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABS65178; ABS65178; Plav_3580.
KEGGipla:Plav_3580.
PATRICi22868963. VBIParLav90819_3685.

Phylogenomic databases

eggNOGiENOG4105ED0. Bacteria.
COG0689. LUCA.
HOGENOMiHOG000229516.
KOiK00989.
OMAiKGKGQGW.
OrthoDBiPOG091H03ML.

Enzyme and pathway databases

BioCyciPLAV402881:GHQA-3626-MONOMER.

Family and domain databases

CDDicd11362. RNase_PH_bact. 1 hit.
Gene3Di3.30.230.70. 1 hit.
HAMAPiMF_00564. RNase_PH. 1 hit.
InterProiIPR001247. ExoRNase_PH_dom1.
IPR015847. ExoRNase_PH_dom2.
IPR027408. PNPase/RNase_PH_dom.
IPR020568. Ribosomal_S5_D2-typ_fold.
IPR002381. RNase_PH_bac-type.
IPR018336. RNase_PH_CS.
[Graphical view]
PfamiPF01138. RNase_PH. 1 hit.
PF03725. RNase_PH_C. 1 hit.
[Graphical view]
SUPFAMiSSF54211. SSF54211. 1 hit.
SSF55666. SSF55666. 1 hit.
TIGRFAMsiTIGR01966. RNasePH. 1 hit.
PROSITEiPS01277. RIBONUCLEASE_PH. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRNPH_PARL1
AccessioniPrimary (citable) accession number: A7HZ45
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: September 11, 2007
Last modified: September 7, 2016
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.