Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

A7HYS8 (TYPH_PARL1) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 42. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative thymidine phosphorylase

EC=2.4.2.4
Alternative name(s):
TdRPase
Gene names
Ordered Locus Names:Plav_3461
OrganismParvibaculum lavamentivorans (strain DS-1 / DSM 13023 / NCIMB 13966) [Complete proteome] [HAMAP]
Taxonomic identifier402881 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhodobiaceaeParvibaculum

Protein attributes

Sequence length505 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Thymidine + phosphate = thymine + 2-deoxy-alpha-D-ribose 1-phosphate. HAMAP-Rule MF_00703

Sequence similarities

Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 505505Putative thymidine phosphorylase HAMAP-Rule MF_00703
PRO_0000314705

Sequences

Sequence LengthMass (Da)Tools
A7HYS8 [UniParc].

Last modified September 11, 2007. Version 1.
Checksum: 703494434635F8A3

FASTA50554,109
        10         20         30         40         50         60 
MSARITPQTP ALQALRMRLH AQHQPVVLMR TDCHVCRAEG LAPRSQVLII AGDRTVQALL 

        70         80         90        100        110        120 
YQIDSDLLKT GQIALSEAAW DALDIHEGDL VQVRHPPLLE SLSAVRARIH GHRLQTTELQ 

       130        140        150        160        170        180 
AIVRDVVDGR YTDVALSAFL TATAVLPLDM QETIHLTRAM VDVGDHLQWQ APIVVDKHCV 

       190        200        210        220        230        240 
GGLPGNRTTP LVVAIAAANG LVMPKTSSRA ITSPAGTADT METLAPVDLD LDTLRKVVEK 

       250        260        270        280        290        300 
EGGCVAWGGA MHLSPADDIF VRIERELDID TQGQLIASVL SKKIAAGATH IVIDIPVGPT 

       310        320        330        340        350        360 
AKVRSRETAE HLAHHLSEVA ASFGLVLRCL FTDGNQPVGR GIGPALEARD VLAVLRNEAD 

       370        380        390        400        410        420 
APQDLCDRVA LVAGAVLELG GVAKEGDGIR LAHETISSGR AWEKFQRICA AQGGFREPPQ 

       430        440        450        460        470        480 
ALYVEPLLAT TSGRAVHIDN RKLSRLAKLA GAPESPAAGI QLQVRLGDEV TRGQSLMFLH 

       490        500 
AQTSGEMAYA LAYVHDIGDI VKIEP 

« Hide

References

[1]"Complete genome sequence and annotation of Parvibaculum lavamentivorans DS-1."
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Saunders E., Brettin T., Bruce D., Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Richardson P.
Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DS-1 / DSM 13023 / NCIMB 13966.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000774 Genomic DNA. Translation: ABS65061.1.
RefSeqYP_001414718.1. NC_009719.1.

3D structure databases

ProteinModelPortalA7HYS8.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING402881.Plav_3461.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABS65061; ABS65061; Plav_3461.
GeneID5455912.
KEGGpla:Plav_3461.
PATRIC22868723. VBIParLav90819_3565.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0213.
HOGENOMHOG000252767.
KOK00758.
OMAESVPGFH.
OrthoDBEOG61ZTGG.

Enzyme and pathway databases

BioCycPLAV402881:GHQA-3507-MONOMER.

Family and domain databases

Gene3D3.40.1030.10. 1 hit.
3.90.1170.30. 1 hit.
HAMAPMF_00703. Thymid_phosp_2.
InterProIPR000312. Glycosyl_Trfase_fam3.
IPR017459. Glycosyl_Trfase_fam3_N_dom.
IPR013102. PYNP_C.
IPR000053. Pyrmidine_PPase.
IPR017872. Pyrmidine_PPase_CS.
IPR028579. Thym_Pase_Put.
IPR013466. Thymidine/AMP_Pase.
[Graphical view]
PANTHERPTHR10515. PTHR10515. 1 hit.
PfamPF02885. Glycos_trans_3N. 1 hit.
PF00591. Glycos_transf_3. 1 hit.
PF07831. PYNP_C. 1 hit.
[Graphical view]
PIRSFPIRSF000478. TP_PyNP. 1 hit.
SMARTSM00941. PYNP_C. 1 hit.
[Graphical view]
SUPFAMSSF47648. SSF47648. 1 hit.
SSF52418. SSF52418. 1 hit.
SSF54680. SSF54680. 1 hit.
TIGRFAMsTIGR02645. ARCH_P_rylase. 1 hit.
PROSITEPS00647. THYMID_PHOSPHORYLASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameTYPH_PARL1
AccessionPrimary (citable) accession number: A7HYS8
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: September 11, 2007
Last modified: May 14, 2014
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families