A7HXK5 (SURE_PARL1) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
5'-nucleotidase surE
EC=3.1.3.5

Alternative name(s):
Nucleoside 5'-monophosphate phosphohydrolase

Gene names

Name:	surE
Ordered Locus Names:	Plav_3031

Organism

Parvibaculum lavamentivorans (strain DS-1 / DSM 13023 / NCIMB 13966) [Complete proteome] [HAMAP]

Taxonomic identifier

402881 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Phyllobacteriaceae › Parvibaculum

Protein attributes

Sequence length	277 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates By similarity. HAMAP MF_00060
Catalytic activity	A 5'-ribonucleotide + H2O = a ribonucleoside + phosphate. HAMAP MF_00060
Cofactor	Binds 1 divalent metal cation per subunit By similarity.
Subcellular location	Cytoplasm Potential HAMAP MF_00060.
Sequence similarities	Belongs to the surE nucleotidase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	Metal-binding Nucleotide-binding
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	5'-nucleotidase activity Inferred from electronic annotation. Source: EC metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW nucleotide binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 277	277	5'-nucleotidase surE HAMAP MF_00060		PRO_0000335266
Sites
	Metal binding	16	1	Divalent metal cation By similarity
	Metal binding	17	1	Divalent metal cation By similarity
	Metal binding	48	1	Divalent metal cation By similarity
	Metal binding	101	1	Divalent metal cation By similarity

Sequences

	Sequence		Length	Mass (Da)
	A7HXK5 [UniParc]. Last modified September 11, 2007. Version 1. Checksum: 1FD57B6DCA5E54A4	FASTA	277	30,326
	10 20 30 40 50 60 MAKSGTKSLR ILVTNDDGIH APGLKVLEKI AHKLSRDVWV VAPEDEQSGS AHSLSLANPL 70 80 90 100 110 120 RVRKLTARKY AVRGTPSDCV LMAVRHILKD EQPDLVVSGI NRGQNIADDV TYSGTIAAAM 130 140 150 160 170 180 EGTQLGIPSI ALSQAFGFSG SANVKWSTAE HFAPDILKKL IAAGWPEEVL ININFPDVVP 190 200 210 220 230 240 GSVTGIEVTR QGKRDQSLVR VEERIDARNN PYYWLGFERI LSNPPQGTDL RAIYESRISI 250 260 270 TPLHMDLTHQ KTAKALNDAL GTLAQPKRRP RSASRKK

References

[1]

"Complete genome sequence and annotation of Parvibaculum lavamentivorans DS-1." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Saunders E., Brettin T., Bruce D., Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Richardson P. Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DS-1 / DSM 13023 / NCIMB 13966.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000774 Genomic DNA. Translation: ABS64638.1.
RefSeq	YP_001414295.1. NC_009719.1.
3D structure databases
ProteinModelPortal	A7HXK5.
ModBase	Search...
Protein-protein interaction databases
STRING	A7HXK5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5456062.
GenomeReviews	Gene locus Plav_3031 in contig CP000774_GR.
KEGG	pla:Plav_3031.
PATRIC	22867843. VBIParLav90819_3130.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0496.
HOGENOM	HBG600532.
OMA	EVWTVAP.
Family and domain databases
HAMAP	MF_00060. SurE. [Tree]
InterPro	IPR002828. SurE-like_Pase/nucleotidase. [Graphical view]
Gene3D	G3DSA:3.40.1210.10. SurE-like_Pase/nucleotidase. 1 hit.
KO	K03787.
Pfam	PF01975. SurE. 1 hit. [Graphical view]
SUPFAM	SSF64167. SurE-like_Pase/nucleotidase. 1 hit.
TIGRFAMs	TIGR00087. SurE. 1 hit.
ProtoNet	Search...

Entry information

Entry name

SURE_PARL1

Accession

Primary (citable) accession number: A7HXK5

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 20, 2008
Last sequence update:	September 11, 2007
Last modified:	December 14, 2011
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program