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A7HXJ6 (SYR_PARL1) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 43. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:Plav_3022
OrganismParvibaculum lavamentivorans (strain DS-1 / DSM 13023 / NCIMB 13966) [Complete proteome] [HAMAP]
Taxonomic identifier402881 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhodobiaceaeParvibaculum

Protein attributes

Sequence length583 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 583583Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_1000071395

Regions

Motif131 – 14111"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
A7HXJ6 [UniParc].

Last modified September 11, 2007. Version 1.
Checksum: B45DB156BABD2C52

FASTA58364,332
        10         20         30         40         50         60 
MNIFRFFEGR VEAALRSLEE EGVLPSGLDL TRVAVEPPRD PSHGDLSTNA AMVLAKPAGM 

        70         80         90        100        110        120 
KPRELAEQLA VKLGGEEAVT EVDVAGPGFI NLRLNPAFWQ ARIPEILRSG PAYGASDVGA 

       130        140        150        160        170        180 
GEAVNVEYVS ANPTGPMHVG HVRGAVFGDA LCNLLEKVGY RVCREYYIND AGGQIEVLAR 

       190        200        210        220        230        240 
SAFLRYREAL GEDIGQIPEG LYPGGYLKPV GQALVAAHGR SLLEKDEPEA LSIVREAAVE 

       250        260        270        280        290        300 
AMMELIRGDL GVLGIVHETF FSELALHRSG FVEQTLKVLE DKGLIYIGEL EPPKGEVPDD 

       310        320        330        340        350        360 
WEARPQTLFR STEFGDDTDR ALKKSDGSWT YFAPDIAYHL DKYNRGYRTL IDVWGADHSG 

       370        380        390        400        410        420 
YIKRMRAAIA GVTDGNAEFD VKICQLVRLF RNGEPVKMSK RSGDFVTLRE VVDEVGKDVV 

       430        440        450        460        470        480 
RFMMLTRKND APLDFDFAKV MEQSRDNPVF YVQYANARIH SVLRNVAEEG TYDLSDGALA 

       490        500        510        520        530        540 
NADFTLLTDE AEMALVRLMA GFPRLVEQAA LAHEPHRIAF YLDDLAAAFH GLWNKGKDDH 

       550        560        570        580 
SLRFIRADHR DVTLARLALI RSAAYVIAAG LAILGVEPTE EMR 

« Hide

References

[1]"Complete genome sequence and annotation of Parvibaculum lavamentivorans DS-1."
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Saunders E., Brettin T., Bruce D., Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Richardson P.
Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DS-1 / DSM 13023 / NCIMB 13966.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000774 Genomic DNA. Translation: ABS64629.1.
RefSeqYP_001414286.1. NC_009719.1.

3D structure databases

ProteinModelPortalA7HXJ6.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING402881.Plav_3022.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABS64629; ABS64629; Plav_3022.
GeneID5456145.
KEGGpla:Plav_3022.
PATRIC22867825. VBIParLav90819_3121.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247214.
KOK01887.
OMARFIMLTR.
OrthoDBEOG6JB13C.
ProtClustDBPRK01611.

Enzyme and pathway databases

BioCycPLAV402881:GHQA-3064-MONOMER.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_PARL1
AccessionPrimary (citable) accession number: A7HXJ6
Entry history
Integrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: September 11, 2007
Last modified: April 16, 2014
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries