A7HWC9 (A7HWC9_PARL1) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Choline dehydrogenase RuleBase RU003969
EC=1.1.99.1 RuleBase RU003969

Gene names

Ordered Locus Names:

Plav_2604

Organism

Parvibaculum lavamentivorans (strain DS-1 / DSM 13023 / NCIMB 13966) [Complete proteome] [HAMAP]

Taxonomic identifier

402881 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Phyllobacteriaceae › Parvibaculum

Protein attributes

Sequence length	562 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine By similarity. SAAS SAAS007867
Catalytic activity	Choline + acceptor = betaine aldehyde + reduced acceptor. RuleBase RU003969 SAAS SAAS007867
Cofactor	FAD By similarity. RuleBase RU003968 SAAS SAAS007867
Pathway	Amine and polyamine biosynthesis; betaine biosynthesis via choline pathway; betaine aldehyde from choline (cytochrome c reductase route): step 1/1. RuleBase RU003969 SAAS SAAS007867
Sequence similarities	Belongs to the GMC oxidoreductase family. RuleBase RU003968

Ontologies

Keywords
Ligand	FAD SAAS SAAS011533 Flavoprotein SAAS SAAS011533 RuleBase RU003968
Molecular function	Oxidoreductase SAAS SAAS007867
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycine betaine biosynthetic process from choline Inferred from electronic annotation. Source: InterPro
Molecular function	choline dehydrogenase activity Inferred from electronic annotation. Source: EC flavin adenine dinucleotide binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A7HWC9 [UniParc]. Last modified September 11, 2007. Version 1. Checksum: B9B2C756D6FAA7C1	FASTA	562	61,640
	10 20 30 40 50 60 MRDQSFEREA DYVIVGAGSA GCVLADRLTA EGRHKVLVLE TGGRDNSVYI KMPTAFSIPL 70 80 90 100 110 120 GMKKYDWGMH AEPEPGLNGR RLHQARGKVI GGSSSINGLA YVRGCAGDFE EWAELGAAGW 130 140 150 160 170 180 DYASVLPYFR RSEDCLYGED AYRGTGGPVG ITNGNNMKNP LYRAFIEAGR QAGYGMTEDY 190 200 210 220 230 240 NGYRQEGFGR MDMTVRDGIR CSTAVAYLKP AMKRDNLEVE MHALATRILM EGKRAVGVEY 250 260 270 280 290 300 RRRGKLHRVK ARREVIVSAS SFNSPKLLML SGIGPAAHLK EHGIPVIHDL PGVGDNLQDH 310 320 330 340 350 360 LEVWVQQTCT QPITLNGTLG PISKLLIGME WFFLKRGLGI SNQFESNGYI RSRAGLKYPD 370 380 390 400 410 420 LQYHFLAGAI AYDGSSAAEG HGFQVHLGAN KPKSRGRVSL NSADPEAPPK LVFNYLTEEA 430 440 450 460 470 480 DKQAYRDGLR LTREIFAQKA FDPYRGDEIS PGPKVRTDAE IDQWVAETAE TAYHPAGTCR 490 500 510 520 530 540 MGADGMAVVD SECRVHGIEA LRVVDSSIMP TLPNGNINAP TIMIGEKAAD HILGKPLLPA 550 560 STADAYHAPN WQENQRVGKP ER

References

[1]

"Complete genome sequence and annotation of Parvibaculum lavamentivorans DS-1." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Saunders E., Brettin T., Bruce D., Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Richardson P. Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DS-1 / DSM 13023 / NCIMB 13966.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000774 Genomic DNA. Translation: ABS64212.1.
RefSeq	YP_001413869.1. NC_009719.1.
3D structure databases
ProteinModelPortal	A7HWC9.
ModBase	Search...
Protein-protein interaction databases
STRING	A7HWC9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5455046.
GenomeReviews	Gene locus Plav_2604 in contig CP000774_GR.
KEGG	pla:Plav_2604.
PATRIC	22866939. VBIParLav90819_2690.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2303.
HOGENOM	HBG734713.
OMA	GPFIQMP.
Family and domain databases
InterPro	IPR011533. Choline_dehydrogenase. IPR012132. GMC_OxRdtase. IPR000172. GMC_OxRdtase_N. IPR007867. GMC_OxRtase_C. [Graphical view]
KO	K00108.
Pfam	PF05199. GMC_oxred_C. 1 hit. PF00732. GMC_oxred_N. 1 hit. [Graphical view]
PIRSF	PIRSF000137. Alcohol_oxidase. 1 hit.
TIGRFAMs	TIGR01810. BetA. 1 hit.
PROSITE	PS00623. GMC_OXRED_1. 1 hit. PS00624. GMC_OXRED_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A7HWC9_PARL1

Accession

Primary (citable) accession number: A7HWC9

Entry history

Integrated into UniProtKB/TrEMBL:	September 11, 2007
Last sequence update:	September 11, 2007
Last modified:	December 14, 2011
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)