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Protein

NAD(P)H dehydrogenase (quinone)

Gene

Plav_2222

Organism
Parvibaculum lavamentivorans (strain DS-1 / DSM 13023 / NCIMB 13966)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

NAD(P)H + a quinone = NAD(P)+ + a hydroquinone.UniRule annotation

Cofactori

FMNUniRule annotationNote: Binds 1 FMN per monomer.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei15NAD(P)UniRule annotation1
Binding sitei102SubstrateUniRule annotation1
Binding sitei137FMNUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi13 – 18FMNUniRule annotation6
Nucleotide bindingi82 – 84FMNUniRule annotation3
Nucleotide bindingi117 – 122FMNUniRule annotation6

GO - Molecular functioni

Keywordsi

Molecular functionOxidoreductase
LigandFlavoprotein, FMN, NAD, NADP, Nucleotide-binding

Enzyme and pathway databases

BioCyciPLAV402881:GHQA-2243-MONOMER.

Protein family/group databases

CAZyiAA6. Auxiliary Activities 6.

Names & Taxonomyi

Protein namesi
Recommended name:
NAD(P)H dehydrogenase (quinone)UniRule annotation (EC:1.6.5.2UniRule annotation)
Alternative name(s):
Flavoprotein WrbA
NAD(P)H:quinone oxidoreductaseUniRule annotation
Short name:
NQOUniRule annotation
Gene namesi
Ordered Locus Names:Plav_2222
OrganismiParvibaculum lavamentivorans (strain DS-1 / DSM 13023 / NCIMB 13966)
Taxonomic identifieri402881 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhodobiaceaeParvibaculum
Proteomesi
  • UP000006377 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000841441 – 203NAD(P)H dehydrogenase (quinone)Add BLAST203

Interactioni

Protein-protein interaction databases

STRINGi402881.Plav_2222.

Structurei

3D structure databases

ProteinModelPortaliA7HVA3.
SMRiA7HVA3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini7 – 194Flavodoxin-likeUniRule annotationAdd BLAST188

Sequence similaritiesi

Belongs to the WrbA family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CS1. Bacteria.
COG0655. LUCA.
HOGENOMiHOG000030539.
KOiK03809.
OMAiKMHAGSS.
OrthoDBiPOG091H03V0.

Family and domain databases

Gene3Di3.40.50.360. 1 hit.
HAMAPiMF_01017. NQOR. 1 hit.
InterProiView protein in InterPro
IPR008254. Flavodoxin/NO_synth.
IPR029039. Flavoprotein-like_sf.
IPR010089. Flavoprotein_WrbA-like.
IPR005025. FMN_Rdtase-like.
IPR037513. NQO.
PfamiView protein in Pfam
PF03358. FMN_red. 1 hit.
SUPFAMiSSF52218. SSF52218. 1 hit.
TIGRFAMsiTIGR01755. flav_wrbA. 1 hit.
PROSITEiView protein in PROSITE
PS50902. FLAVODOXIN_LIKE. 1 hit.

Sequencei

Sequence statusi: Complete.

A7HVA3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTGKTKVLVL YHSSYGHIET LAKAVAEGAA SQAGTEVLLK RVPETMPADA
60 70 80 90 100
MANAGMKVEQ EAPVATPQEL GDYDAVIFGT PTRFGNMTGQ MRTFLDQTGG
110 120 130 140 150
LWAKGALVGK VGSVFTSTGT GGGNETTITS FHTNLFHHGM VVVGLPYSVG
160 170 180 190 200
TELFDISEVR GGSPYGASTL AGGDGKRQPT EKELSLARKQ GAHVASIAAK

LKA
Length:203
Mass (Da):21,099
Last modified:September 11, 2007 - v1
Checksum:iC52BC1A0963C9B21
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000774 Genomic DNA. Translation: ABS63836.1.
RefSeqiWP_012111141.1. NC_009719.1.

Genome annotation databases

EnsemblBacteriaiABS63836; ABS63836; Plav_2222.
KEGGipla:Plav_2222.

Similar proteinsi

Entry informationi

Entry nameiNQOR_PARL1
AccessioniPrimary (citable) accession number: A7HVA3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: September 11, 2007
Last modified: December 20, 2017
This is version 66 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families