A7HV37 (A7HV37_PARL1) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Peptide methionine sulfoxide reductase MsrA HAMAP-Rule MF_01401
Short name=Protein-methionine-S-oxide reductase HAMAP-Rule MF_01401
EC=1.8.4.11 HAMAP-Rule MF_01401

Alternative name(s):
Peptide-methionine (S)-S-oxide reductase HAMAP-Rule MF_01401

Gene names

Name:	msrA HAMAP-Rule MF_01401
Ordered Locus Names:	Plav_2156

Organism

Parvibaculum lavamentivorans (strain DS-1 / DSM 13023 / NCIMB 13966) [Complete proteome] [HAMAP] EMBL ABS63770.1

Taxonomic identifier

402881 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Phyllobacteriaceae › Parvibaculum › Parvibaculum lavamentivorans

Protein attributes

Sequence length	218 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine By similarity. HAMAP-Rule MF_01401
Catalytic activity	L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin. HAMAP-Rule MF_01401 SAAS SAAS002569 Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (S)-S-oxide + thioredoxin. HAMAP-Rule MF_01401 SAAS SAAS002569
Sequence similarities	Belongs to the MsrA Met sulfoxide reductase family. HAMAP-Rule MF_01401

Ontologies

Keywords
Molecular function	Oxidoreductase HAMAP-Rule MF_01401 SAAS SAAS002569 EMBL ABS63770.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	cellular protein modification process Inferred from electronic annotation. Source: HAMAP
Molecular_function	peptide-methionine (S)-S-oxide reductase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	54	1	By similarity HAMAP-Rule MF_01401

Sequences

	Sequence		Length	Mass (Da)
	A7HV37 [UniParc]. Last modified September 11, 2007. Version 1. Checksum: 95A5D34515D62023	FASTA	218	23,733
	10 20 30 40 50 60 MFNLRKKTEM PAPGEALPGR DFAIPTASRH FVNGADLKGP YPEGSETAIF GLGCFWGAER 70 80 90 100 110 120 KFWELPGVHV TAVGYAGGYS PNPTYEEVCS GRTGHNEVVL VVYDPKKVSY EALLKTFWES 130 140 150 160 170 180 HNPTQGMRQG NDVGTQYRSG IYVTSPAQRE AAESSRAAYE AELRKQGYDV ITTEILDAPE 190 200 210 FYFAEDYHQQ YLAKNPAGYC GLGGTGVSCP IGTGVNAA

References

[1]

"Complete genome sequence and annotation of Parvibaculum lavamentivorans DS-1." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Saunders E., Brettin T., Bruce D., Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Richardson P. Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DS-1 / DSM 13023 / NCIMB 13966.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000774 Genomic DNA. Translation: ABS63770.1.
RefSeq	YP_001413427.1. NC_009719.1.
3D structure databases
ProteinModelPortal	A7HV37.
SMR	A7HV37. Positions 12-210.
ModBase	Search...
Protein-protein interaction databases
STRING	402881.Plav_2156.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABS63770; ABS63770; Plav_2156.
GeneID	5453395.
KEGG	pla:Plav_2156.
PATRIC	22865997. VBIParLav90819_2224.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0225.
HOGENOM	HOG000263862.
KO	K07304.
OMA	SAIYCTS.
Enzyme and pathway databases
BioCyc	PLAV402881:GHQA-2205-MONOMER.
Family and domain databases
Gene3D	3.30.1060.10. 1 hit.
HAMAP	MF_01401. MsrA.
InterPro	IPR002569. Met_Sox_Rdtase_MsrA. [Graphical view]
Pfam	PF01625. PMSR. 1 hit. [Graphical view]
SUPFAM	SSF55068. MsrA. 1 hit.
TIGRFAMs	TIGR00401. msrA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A7HV37_PARL1

Accession

Primary (citable) accession number: A7HV37

Entry history

Integrated into UniProtKB/TrEMBL:	September 11, 2007
Last sequence update:	September 11, 2007
Last modified:	May 1, 2013
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)