SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

A7HSW4

- ASSY_PARL1

UniProt

A7HSW4 - ASSY_PARL1

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Argininosuccinate synthase
Gene
argG, Plav_1377
Organism
Parvibaculum lavamentivorans (strain DS-1 / DSM 13023 / NCIMB 13966)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-citrulline + L-aspartate = AMP + diphosphate + N(omega)-(L-arginino)succinate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei41 – 411ATP; via amide nitrogen and carbonyl oxygen By similarity
Binding sitei92 – 921Citrulline By similarity
Binding sitei97 – 971Citrulline By similarity
Binding sitei122 – 1221ATP; via amide nitrogen By similarity
Binding sitei124 – 1241Aspartate By similarity
Binding sitei128 – 1281Aspartate By similarity
Binding sitei128 – 1281Citrulline By similarity
Binding sitei129 – 1291Aspartate By similarity
Binding sitei132 – 1321Citrulline By similarity
Binding sitei183 – 1831Citrulline By similarity
Binding sitei192 – 1921Citrulline By similarity
Binding sitei268 – 2681Citrulline By similarity
Binding sitei280 – 2801Citrulline By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi14 – 229ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. argininosuccinate synthase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. arginine biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Ligase

Keywords - Biological processi

Amino-acid biosynthesis, Arginine biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciPLAV402881:GHQA-1394-MONOMER.
UniPathwayiUPA00068; UER00113.

Names & Taxonomyi

Protein namesi
Recommended name:
Argininosuccinate synthase (EC:6.3.4.5)
Alternative name(s):
Citrulline--aspartate ligase
Gene namesi
Name:argG
Ordered Locus Names:Plav_1377
OrganismiParvibaculum lavamentivorans (strain DS-1 / DSM 13023 / NCIMB 13966)
Taxonomic identifieri402881 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhodobiaceaeParvibaculum
ProteomesiUP000006377: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 410410Argininosuccinate synthaseUniRule annotation
PRO_0000321316Add
BLAST

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi402881.Plav_1377.

Structurei

3D structure databases

ProteinModelPortaliA7HSW4.
SMRiA7HSW4. Positions 10-402.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0137.
HOGENOMiHOG000230093.
KOiK01940.
OMAiAPPEEAY.
OrthoDBiEOG6K9QCV.

Family and domain databases

Gene3Di3.40.50.620. 1 hit.
3.90.1260.10. 1 hit.
HAMAPiMF_00005. Arg_succ_synth_type1.
InterProiIPR001518. Arginosuc_synth.
IPR018223. Arginosuc_synth_CS.
IPR023434. Arginosuc_synth_type_1_subfam.
IPR024074. AS_cat/multimer_dom_body.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PfamiPF00764. Arginosuc_synth. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00032. argG. 1 hit.
PROSITEiPS00564. ARGININOSUCCIN_SYN_1. 1 hit.
PS00565. ARGININOSUCCIN_SYN_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A7HSW4-1 [UniParc]FASTAAdd to Basket

« Hide

MSGATKDVKK VVLAYSGGLD TSVILKWLQE TYGCEVVTFT ADLGQGEELE    50
PARKKAEMLG VKEIYIEDLR EEFVRDFVFP MFRANAVYEG VYLLGTSIAR 100
PLIAKRQIEI ARQTGADAVC HGSTGKGNDQ VRFELGYAAL NPEIKIIAPW 150
REWDLTSRTK LIEFAEKHQI PIAKDKRGEA PFSVDANLLH ISAEGKVLED 200
PADEAPEYVY SRSVRPEDAP DTPTYVEVGF EKGDAVSIDG VKMSPATLLT 250
KLNELGGANG IGRLDLVENR FVGMKSRGVY ETPGGTVLLV AHRAMESITL 300
DRGAAHLKDE LMPRYAELIY NGFWWSPERE MLQALIDKSQ EMVTGSVRLK 350
LYKGMATVVG RSSPYSLYSM AHVTFEEDAG AYDQKDAAGF IRLNALRLRL 400
LAARNNRTKK 410
Length:410
Mass (Da):45,518
Last modified:September 11, 2007 - v1
Checksum:i7F9325BD60E2BD34
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000774 Genomic DNA. Translation: ABS62997.1.
RefSeqiYP_001412654.1. NC_009719.1.

Genome annotation databases

EnsemblBacteriaiABS62997; ABS62997; Plav_1377.
GeneIDi5455880.
KEGGipla:Plav_1377.
PATRICi22864370. VBIParLav90819_1421.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000774 Genomic DNA. Translation: ABS62997.1 .
RefSeqi YP_001412654.1. NC_009719.1.

3D structure databases

ProteinModelPortali A7HSW4.
SMRi A7HSW4. Positions 10-402.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 402881.Plav_1377.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABS62997 ; ABS62997 ; Plav_1377 .
GeneIDi 5455880.
KEGGi pla:Plav_1377.
PATRICi 22864370. VBIParLav90819_1421.

Phylogenomic databases

eggNOGi COG0137.
HOGENOMi HOG000230093.
KOi K01940.
OMAi APPEEAY.
OrthoDBi EOG6K9QCV.

Enzyme and pathway databases

UniPathwayi UPA00068 ; UER00113 .
BioCyci PLAV402881:GHQA-1394-MONOMER.

Family and domain databases

Gene3Di 3.40.50.620. 1 hit.
3.90.1260.10. 1 hit.
HAMAPi MF_00005. Arg_succ_synth_type1.
InterProi IPR001518. Arginosuc_synth.
IPR018223. Arginosuc_synth_CS.
IPR023434. Arginosuc_synth_type_1_subfam.
IPR024074. AS_cat/multimer_dom_body.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view ]
Pfami PF00764. Arginosuc_synth. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00032. argG. 1 hit.
PROSITEi PS00564. ARGININOSUCCIN_SYN_1. 1 hit.
PS00565. ARGININOSUCCIN_SYN_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete genome sequence and annotation of Parvibaculum lavamentivorans DS-1."
    Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Saunders E., Brettin T., Bruce D., Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Richardson P.
    Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DS-1 / DSM 13023 / NCIMB 13966.

Entry informationi

Entry nameiASSY_PARL1
AccessioniPrimary (citable) accession number: A7HSW4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: September 11, 2007
Last modified: May 14, 2014
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi