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A7HQP8 (A7HQP8_PARL1) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 37. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Serine hydroxymethyltransferase 1 HAMAP MF_00051
Short name=SHMT 1 HAMAP MF_00051
Short name=Serine methylase 1 HAMAP MF_00051
EC=2.1.2.1 HAMAP MF_00051
Gene names
Name:glyA1 HAMAP MF_00051
Ordered Locus Names:Plav_0608
OrganismParvibaculum lavamentivorans (strain DS-1 / DSM 13023 / NCIMB 13966) [Complete proteome] [HAMAP]
Taxonomic identifier402881 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Phyllobacteriaceae › Parvibaculum

Protein attributes

Sequence length420 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Interconversion of serine and glycine By similarity. RuleBase RU000585 HAMAP MF_00051

Catalytic activity

5,10-methylenetetrahydrofolate + glycine + H2O = tetrahydrofolate + L-serine. RuleBase RU000585 HAMAP MF_00051

Cofactor

Pyridoxal phosphate By similarity. RuleBase RU000585 HAMAP MF_00051

Pathway

One-carbon metabolism; tetrahydrofolate interconversion. HAMAP MF_00051

One-carbon metabolism; tetrahydrofolate pathway. RuleBase RU000585

Subunit structure

Homotetramer By similarity. HAMAP MF_00051

Subcellular location

Cytoplasm By similarity HAMAP MF_00051.

Sequence similarities

Belongs to the SHMT family. RuleBase RU004104 HAMAP MF_00051

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Amino acid modifications

Modified residue2331N6-(pyridoxal phosphate)lysine By similarity HAMAP MF_00051

Sequences

Sequence LengthMass (Da)Tools
A7HQP8 [UniParc].

Last modified September 11, 2007. Version 1.
Checksum: D4307EA24FCD3586

FASTA42045,217
        10         20         30         40         50         60 
MTTSQERARL AQSDNEIFLA LKGEEARQRA GLELIPSENY AFPEVLTLLG SAFTNKYSEG 

        70         80         90        100        110        120 
YPGRRYYGGQ DYTDRIETLA RDRAKALFRA EHANVQPLSG SPMNQAVYLG LLEPGDTILA 

       130        140        150        160        170        180 
MDLSHGGHLT HGAPVSHMGR LFNFVRYKTD PTNGAIDFDH LRAVARETKP RLVVCGYSSY 

       190        200        210        220        230        240 
PRDYDYADFK RVADEVGALT MADVSHIGGL IAANVMRNPL DAGFDVMTTT THKSLRGPRG 

       250        260        270        280        290        300 
GLILCKAEFA RKIDASVFPG LQGGPHMNQV AAAAVTFRLA AMPAFRDYAE QVLANAKALA 

       310        320        330        340        350        360 
AALMERQVKL VTGGTDNHLL VIDTVASFGI DGAVAQEALD RVGLTTNKQV IPDDPNPPMR 

       370        380        390        400        410        420 
PSGLRLGTPA ATARGMGHKE MAEIAEIIAA ALNAKGDAAT ETALAARTHK LTSRFPVDGL

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References

[1]"Complete genome sequence and annotation of Parvibaculum lavamentivorans DS-1."
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Saunders E., Brettin T., Bruce D., Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Richardson P.
Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DS-1 / DSM 13023 / NCIMB 13966.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000774 Genomic DNA. Translation: ABS62231.1.
RefSeqYP_001411888.1. NC_009719.1.

3D structure databases

ProteinModelPortalA7HQP8.
SMRA7HQP8. Positions 9-412.
ModBaseSearch...

Protein-protein interaction databases

STRINGA7HQP8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5455307.
GenomeReviewsGene locus Plav_0608 in contig CP000774_GR.
KEGGpla:Plav_0608.
PATRIC22862772. VBIParLav90819_0629.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0112.
HOGENOMHBG301263.
OMANGAHENA.
ProtClustDBCLSK911453.

Family and domain databases

HAMAPMF_00051. SHMT.
[Tree]
InterProIPR015424. PyrdxlP-dep_Trfase_major_dom.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
IPR001085. Ser_HO-MeTrfase.
IPR019798. Ser_HO-MeTrfase_PLP_BS.
[Graphical view]
Gene3DG3DSA:3.40.640.10. PyrdxlP-dep_Trfase_major_sub1. 1 hit.
G3DSA:3.90.1150.10. PyrdxlP-dep_Trfase_major_sub2. 1 hit.
KOK00600.
PANTHERPTHR11680. Gly_HO-Metrfase. 1 hit.
PfamPF00464. SHMT. 1 hit.
[Graphical view]
PIRSFPIRSF000412. SHMT. 1 hit.
SUPFAMSSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
PROSITEPS00096. SHMT. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA7HQP8_PARL1
AccessionPrimary (citable) accession number: A7HQP8
Entry history
Integrated into UniProtKB/TrEMBL: September 11, 2007
Last sequence update: September 11, 2007
Last modified: December 14, 2011
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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