Skip Header

Contribute Send feedback
Read comments (?) or add your own

A7HNZ7 (A7HNZ7_PARL1) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 35. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
DNA gyrase subunit B RuleBase RU003363 HAMAP MF_01898
EC=5.99.1.3 RuleBase RU003363 HAMAP MF_01898
Gene names
Name:gyrB HAMAP MF_01898
Ordered Locus Names:Plav_0007
OrganismParvibaculum lavamentivorans (strain DS-1 / DSM 13023 / NCIMB 13966) [Complete proteome] [HAMAP]
Taxonomic identifier402881 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Phyllobacteriaceae › Parvibaculum

Protein attributes

Sequence length814 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

DNA gyrase negatively supercoils closed circular double-stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings By similarity. RuleBase RU003363 HAMAP MF_01898

Catalytic activity

ATP-dependent breakage, passage and rejoining of double-stranded DNA. RuleBase RU003363 SAAS SAAS002288 HAMAP MF_01898

Subunit structure

Made up of two chains. The A chain is responsible for DNA breakage and rejoining; the B chain catalyzes ATP hydrolysis. The enzyme forms an A2B2 tetramer By similarity. HAMAP MF_01898

Subcellular location

Cytoplasm By similarity HAMAP MF_01898.

Sequence similarities

Belongs to the type II topoisomerase family. HAMAP MF_01898 RuleBase RU000380

Contains 1 Toprim domain. SAAS SAAS002288 HAMAP MF_01898

Sequences

Sequence LengthMass (Da)Tools
A7HNZ7 [UniParc].

Last modified September 11, 2007. Version 1.
Checksum: F0F3DDA1CCF0B508

FASTA81489,541
        10         20         30         40         50         60 
MTTPADDTPE EYGAESIKVL KGLDAVRKRP GMYIGDTDDG SGLHHMVYEV VDNSIDEALA 

        70         80         90        100        110        120 
GYCDAVNVRL NADGSVTVMD NGRGIPVEIH KGEGVSAAEV IMTQLHAGGK FDQNSYKVSG 

       130        140        150        160        170        180 
GLHGVGVSVV NALSDWLEMR IWRAGKEHRI RFQHGVPDAP LEATGPAPIG ADGKPVTGTE 

       190        200        210        220        230        240 
ITFHPSSETF TQTEFDFATL EHRLRELAFL NSGVKINLTD HRGVEPKEVK LMYEGGLEAF 

       250        260        270        280        290        300 
VRFLDRTKAP LIQKPIAIRA EREGITVEVA MWWNDSYHEN VLCFTNNIPQ RDGGTHLAGF 

       310        320        330        340        350        360 
RGALTRVINS YANESGIAKK EKVSLTGDDA REGLTCVLSV KVPDPKFSSQ TKDKLVSSEV 

       370        380        390        400        410        420 
RPVVEGLVND ALSTWLEEHP AEARQVVTKV VEAAAAREAA RKARELTRRK GALDVSSLPG 

       430        440        450        460        470        480 
KLADCQERDP AKSELFIVEG DSAGGSAKQA RDRSNQAVLP LRGKILNVER ARFDKMLSSN 

       490        500        510        520        530        540 
EIGTLITALG AGIGRDDFNI DKLRYHKIII MTDADVDGAH IRTLLLTFFY RQMPEVIERG 

       550        560        570        580        590        600 
HLYIAQPPLY KVRRGTSETY LKNEKALGDY LISTGLEDMV LTLHDGSQRA GPDLSDIVAR 

       610        620        630        640        650        660 
ARSVRAVLEG LPTKYPHFVV EQAAIAGALN PKALAEPEHA REAAAYIARR LDLLSEETER 

       670        680        690        700        710        720 
GWTGETTQDG GLRFAREVRG VREEVSIDGP LIASADARRL DSYTEHLQEV YVKAATLRRK 

       730        740        750        760        770        780 
DDSHIIRSPS QLLDAVMAAG TKGNTVQRYK GLGEMNPGQL WETTLDRDAR SLLQVKIREL 

       790        800        810 
DDADDLFVKL MGDVVEPRRD FIRENALNVA NLDI

« Hide

References

[1]"Complete genome sequence and annotation of Parvibaculum lavamentivorans DS-1."
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Saunders E., Brettin T., Bruce D., Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Richardson P.
Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DS-1 / DSM 13023 / NCIMB 13966.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000774 Genomic DNA. Translation: ABS61630.1.
RefSeqYP_001411287.1. NC_009719.1.

3D structure databases

ProteinModelPortalA7HNZ7.
SMRA7HNZ7. Positions 17-392.
ModBaseSearch...

Protein-protein interaction databases

STRINGA7HNZ7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5455210.
GenomeReviewsGene locus Plav_0007 in contig CP000774_GR.
KEGGpla:Plav_0007.
PATRIC22861510. VBIParLav90819_0007.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0187.
HOGENOMHBG304889.
OMADCSSRDP.

Family and domain databases

HAMAPMF_01898. GyrB.
[Tree]
InterProIPR003594. ATPase-like_ATP-bd.
IPR011557. GyrB.
IPR020568. Ribosomal_S5_D2-typ_fold.
IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
IPR001241. Topo_IIA.
IPR013759. Topo_IIA_B/N_ab.
IPR002288. Topo_IIA_B_C.
IPR013506. Topo_IIA_bsu_dom2.
IPR013760. Topo_IIA_cen.
IPR018522. TopoIIA_CS.
IPR006171. Toprim_domain.
[Graphical view]
Gene3DG3DSA:3.30.565.10. ATP_bd_ATPase. 1 hit.
G3DSA:3.30.230.10. Ribosomal_S5_D2-type_fold. 1 hit.
G3DSA:3.40.50.670. Topo_IIA_B/N_ab. 2 hits.
KOK02470.
PfamPF00204. DNA_gyraseB. 1 hit.
PF00986. DNA_gyraseB_C. 1 hit.
PF02518. HATPase_c. 1 hit.
PF01751. Toprim. 1 hit.
[Graphical view]
PRINTSPR00418. TPI2FAMILY.
SMARTSM00387. HATPase_c. 1 hit.
SM00433. TOP2c. 1 hit.
[Graphical view]
SUPFAMSSF55874. ATP_bd_ATPase. 1 hit.
SSF54211. Ribosomal_S5_D2-typ_fold. 1 hit.
SSF56719. Topo_IIA_cen. 1 hit.
TIGRFAMsTIGR01059. GyrB. 1 hit.
PROSITEPS00177. TOPOISOMERASE_II. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA7HNZ7_PARL1
AccessionPrimary (citable) accession number: A7HNZ7
Entry history
Integrated into UniProtKB/TrEMBL: September 11, 2007
Last sequence update: September 11, 2007
Last modified: January 25, 2012
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info