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A7HMJ3 (A7HMJ3_FERNB) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 42. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Methylenetetrahydrofolate reductase RuleBase RU003862

EC=1.5.1.20 RuleBase RU003862
Gene names
Ordered Locus Names:Fnod_1279 EMBL ABS61126.1
OrganismFervidobacterium nodosum (strain ATCC 35602 / DSM 5306 / Rt17-B1) [Complete proteome] [HAMAP] EMBL ABS61126.1
Taxonomic identifier381764 [NCBI]
Taxonomic lineageBacteriaThermotogaeThermotogalesThermotogaceaeFervidobacterium

Protein attributes

Sequence length313 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

5-methyltetrahydrofolate + NAD(P)+ = 5,10-methylenetetrahydrofolate + NAD(P)H. RuleBase RU003862

Cofactor

FAD By similarity. RuleBase RU003862

Sequence similarities

Belongs to the methylenetetrahydrofolate reductase family. RuleBase RU003862

Ontologies

Keywords
   LigandFAD RuleBase RU003862
Flavoprotein
   Molecular functionOxidoreductase RuleBase RU003862
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processmethionine metabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functionmethylenetetrahydrofolate reductase (NAD(P)H) activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
A7HMJ3 [UniParc].

Last modified September 11, 2007. Version 1.
Checksum: B78F4416EC01F4FD

FASTA31335,602
        10         20         30         40         50         60 
MKIVEKLRNE KIVSIEIIPP KRGEDVEKIF ATLDKLMDYN ISFINITRHP SEIDYLETEN 

        70         80         90        100        110        120 
GIIKVQKIKR PGTIGLTAAL MKRYNIDVVP HLVCKGMNKF EMEDILIDLS IMGVENVFVV 

       130        140        150        160        170        180 
RGEEVKSVAK SDYKYASDLV KQISDMNNGR YLYTEAKPTN FCIGVAGYPE KHFEAPNLDV 

       190        200        210        220        230        240 
DLRFLKQKVD NGADFIITQM VFDAAIYEKF VEKSRSMGIN IPIIPGVKPV VSKKSIYSIP 

       250        260        270        280        290        300 
KKFFVNIPQK FVEKMEEAKS ESEEFEIGVR FTVELIKNLL EKDAPGVHIF TMGRGEEVCK 

       310 
VLKLLREGGI LNV 

« Hide

References

[1]"Complete sequence of Fervidobacterium nodosum Rt17-B1."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Saunders E., Brettin T., Bruce D., Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. expand/collapse author list , Mikhailova N., Nelson K., Gogarten J.P., Noll K., Richardson P.
Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 35602 / DSM 5306 / Rt17-B1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000771 Genomic DNA. Translation: ABS61126.1.
RefSeqYP_001410783.1. NC_009718.1.

3D structure databases

ProteinModelPortalA7HMJ3.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING381764.Fnod_1279.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABS61126; ABS61126; Fnod_1279.
GeneID5452562.
KEGGfno:Fnod_1279.
PATRIC21884099. VBIFerNod12464_1332.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0685.
HOGENOMHOG000246233.
KOK00297.
OMAAIKQCED.
OrthoDBEOG6D2KVW.

Enzyme and pathway databases

BioCycFNOD381764:GC5M-1330-MONOMER.

Family and domain databases

Gene3D3.20.20.220. 1 hit.
InterProIPR029041. FAD-linked_oxidoreductase-like.
IPR003171. Mehydrof_redctse.
[Graphical view]
PfamPF02219. MTHFR. 1 hit.
[Graphical view]
SUPFAMSSF51730. SSF51730. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA7HMJ3_FERNB
AccessionPrimary (citable) accession number: A7HMJ3
Entry history
Integrated into UniProtKB/TrEMBL: September 11, 2007
Last sequence update: September 11, 2007
Last modified: June 11, 2014
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)