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A7HLU1 (A7HLU1_FERNB) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 54. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length364 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201

Catalytic activity

L-alanine = D-alanine. HAMAP-Rule MF_01201 SAAS SAAS009006

Cofactor

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01201 SAAS SAAS009006

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP-Rule MF_01201

Sequence similarities

Belongs to the alanine racemase family. HAMAP-Rule MF_01201 RuleBase RU004188

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site361Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
Active site2531Proton acceptor; specific for L-alanine By similarity HAMAP-Rule MF_01201
Binding site1301Substrate By similarity HAMAP-Rule MF_01201
Binding site3011Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01201

Amino acid modifications

Modified residue361N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

Sequence LengthMass (Da)Tools
A7HLU1 [UniParc].

Last modified September 11, 2007. Version 1.
Checksum: A0A1F4014D6CC6C3

FASTA36441,302
        10         20         30         40         50         60 
MESRRTYAVI NVRNYLDNLR FFQTHCAPAK VMPVVKANAY GHGAVQLAKA AQKIGIDYFA 

        70         80         90        100        110        120 
VAFLEEAIEL RKHGISKDIL VFNYIEPDLL HIAMENNITI TLYSWEQLWK YTKYVWRPKA 

       130        140        150        160        170        180 
HIKIDTGMRR LGVYPEEAKD FIESARNVGF EVEGAYTHFA VADSLDDEDV KFTQQQVEKF 

       190        200        210        220        230        240 
ANLNLDVKIK HLCNSGASVS KIVNCFDYVR VGIASYGLQP SDSVYSEQLK PVLSWKTTVS 

       250        260        270        280        290        300 
HVKTIQPGDS VSYGRTFKAF TEMRIATIPV GYADGYWRHL SNKGYVLIHG EKCPIIGRVC 

       310        320        330        340        350        360 
MDQFMVDVTH LEDVKIGDEV ILIGKQGDNI ITAEEIAKLV GTINYEVTCR ISERVPRKYE 


GLEL 

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References

[1]"Complete sequence of Fervidobacterium nodosum Rt17-B1."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Saunders E., Brettin T., Bruce D., Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N. expand/collapse author list , Mikhailova N., Nelson K., Gogarten J.P., Noll K., Richardson P.
Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 35602 / DSM 5306 / Rt17-B1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000771 Genomic DNA. Translation: ABS60874.1.
RefSeqYP_001410531.1. NC_009718.1.

3D structure databases

ProteinModelPortalA7HLU1.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING381764.Fnod_1025.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABS60874; ABS60874; Fnod_1025.
GeneID5452640.
KEGGfno:Fnod_1025.
PATRIC21883549. VBIFerNod12464_1073.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0787.
HOGENOMHOG000031444.
KOK01775.
OMAMAHFADA.
OrthoDBEOG6PP9NJ.
ProtClustDBCLSK975944.

Enzyme and pathway databases

BioCycFNOD381764:GC5M-1059-MONOMER.
UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. SSF50621. 1 hit.
TIGRFAMsTIGR00492. alr. 1 hit.
PROSITEPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA7HLU1_FERNB
AccessionPrimary (citable) accession number: A7HLU1
Entry history
Integrated into UniProtKB/TrEMBL: September 11, 2007
Last sequence update: September 11, 2007
Last modified: February 19, 2014
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)